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Gastrointestinal Disturbances in Autism Spectrum Disorder

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Pediatric Neurogastroenterology

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Abstract

Autism spectrum disorders (ASD) are complex neurobehavioral conditions with varied phenotypes involving multiple organ systems. Gastrointestinal (GI) manifestations are widely reported among children with ASD. Due to sensory and communicative limitations inherent to ASD, GI conditions may present atypically resulting in diagnostic challenges. Substantial gaps exist in the current understanding of the pathophysiology of ASD and their close link with GI comorbidities. Further understanding of these links may lead to the creation of novel therapies for this population. Here, we review the prevalence, pathophysiology, diagnosis, and management of GI disease in children with ASD.

Lena Gottesman-Katz and Jonathan Miller were co-first authors.

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Authors and Affiliations

  1. Pediatric Gastroenterology, Hackensack Meridian Health, Jersey Shore University Medical Center, Neptune, NJ, USA

    Lena Gottesman-Katz

  2. Pediatric Gastroenterology, New York Presbyterian/Columbia University Irving Medical Center, New York, NY, USA

    Jonathan Miller

  3. Department of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA

    Kara Gross Margolis

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  1. Lena Gottesman-Katz
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  2. Jonathan Miller
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  3. Kara Gross Margolis
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Correspondence to Kara Gross Margolis .

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Editors and Affiliations

  1. Division of Gastroenterology, Department of Pediatrics, Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal, QC, Canada

    Christophe Faure

  2. Department of Gastroenterology, Hepatology and Liver Transplant, Queensland Children’s Hospital School of Medicine University of Queensland, Brisbane, QLD, Australia

    Nikhil Thapar

  3. Division of Pediatric Gastroenterology, Nationwide Children’s Hospital, Columbus, OH, USA

    Carlo Di Lorenzo

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Gottesman-Katz, L., Miller, J., Margolis, K.G. (2022). Gastrointestinal Disturbances in Autism Spectrum Disorder. In: Faure, C., Thapar, N., Di Lorenzo, C. (eds) Pediatric Neurogastroenterology. Springer, Cham. https://doi.org/10.1007/978-3-031-15229-0_28

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