Skip to main content

Seborrhoeic Dermatitis

  • Chapter
  • First Online:
European Handbook of Dermatological Treatments
  • 43 Accesses

Abstract

Seborrhoeic dermatitis is a common chronic inflammatory disorder of the skin, characterized by scaly, erythematous patches mainly involving the sebum-rich areas like the scalp, face back and upper chest. The pathogenesis of seborrheic dermatitis is not fully understood, but the colonization of skin with lipophilic yeasts Malassezia, along with genetic, environmental and overall health factors, contribute to its pathogenesis. A large number of treatment modalities are used, which include the clearance of fungus by the application of antifungals like pyrithione zinc or ketoconazole-containing shampoos, keratolytics like selenium sulphide, reducing the inflammation by topical corticosteroids and reducing sebum production by oral retinoids.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 349.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 449.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Brenner S, Horwitz C. Possible nutrient mediators in psoriasis and seborrheic dermatitis. II. Nutrient mediators: essential fatty acids; vitamins A, E and D; vitamins B1, B2, B6, niacin and biotin; vitamin C selenium; zinc; iron. World Rev Nutr Diet. 1988;55:165–82.

    Article  CAS  PubMed  Google Scholar 

  • Caputo R, Barbareschi M, Gorani A, Veraldi S. Itraconazole: new horizons. In: Congress of the European academy of dermatology & venereology. 2002. 16(suppl 1), pp. 254–254.

    Google Scholar 

  • Cook BA, Warshaw EM. Role of topical calcineurin inhibitors in the treatment of seborrheic dermatitis: a review of pathophysiology, safety, and efficacy. Am J Clin Dermatol. 2009;10:105–16.

    Article  Google Scholar 

  • Danby FW, Maddin WS, Margesson LJ, Rosenthal D. A randomized, double blind, placebo controlled trial of ketoconazole 2% shampoo versus selenium sulfide 2.5% shampoo in the treatment of moderate to severe dandruff. J Am Acad Dermatol. 1993;29:1008–12.

    Article  CAS  PubMed  Google Scholar 

  • Del Rosso JQ. Adult seborrheic dermatitis: a status report on practical topical management. J Clin Aesthet Dermatol. 2011;4:32–8.

    PubMed  PubMed Central  Google Scholar 

  • Dreno B, Moyse D. Lithium gluconate in the treatment of seborrhoeic dermatitis: a multicenter, randomised, double blind study versus placebo. Eur J Dermatol. 2002;12:549–52.

    CAS  PubMed  Google Scholar 

  • Ford GP, Farr PM, Ive FA, Shuster S. The response of seborrheic dermatitis to ketoconazole. Br J Dermatol. 1984;111:603–7.

    Article  CAS  PubMed  Google Scholar 

  • Fredriksson T. Controlled comparison of clinitar shampoo and Selsun shampoo in the treatment of seborrheic dermatitis. Br J Clin Pract. 1985;39:25–8.

    Article  CAS  PubMed  Google Scholar 

  • Gupta AK, Bluhm R. Seborrheic dermatitis. J Eur Acad Dermatol Venereol. 2004;18(1):13–26; quiz, 19–20.

    Article  CAS  PubMed  Google Scholar 

  • Gupta AK, Madzia SE, Batra R. Etiology and management of seborrheic dermatitis. Dermatology. 2004;208(2):89–93.

    Article  PubMed  Google Scholar 

  • Mahe A, Simon F, Coulibaly S, Tounkara A, Bobin P. Predictive value of seborrheic dermatitis and other common dermatoses for HIV infection in Bamako, Mali. J Am Acad Dermatol. 1996;34(6):1084–6.

    Article  CAS  PubMed  Google Scholar 

  • Mastrolonardo M, Diaferio A, Logroscino G. Seborrheic dermatitis, increased sebum excretion, and Parkinson’s disease: a survey of (im)possible links. Med Hypotheses. 2003;60:907–11.

    Article  CAS  PubMed  Google Scholar 

  • Mokos ZB, Kralj M, Basta-Juzbasic A, Jukic IL. Seborrheic dermatitis: an update. Acta Dermatovenerol Croat. 2012;20(2):98–104.

    Google Scholar 

  • Orfanos CE, Zouboulis CC. Oral retinoids in the treatment of seborrhoea and acne. Dermatology. 1998;196:140–7.

    Article  CAS  PubMed  Google Scholar 

  • Ortonne JP, Lacour JP, Vitetta A, Le Fichoux Y. Comparative study of ketoconazole 2% foaming gel and betamethasone dipropionate 0.05% lotion in the treatment of seborrheic dermatitis in adults. Dermatology. 1992;184:275–80.

    Article  CAS  PubMed  Google Scholar 

  • Peter RU, Richarz-Barthauer U. Successful treatment and prophylaxis of scalp seborrhoeic dermatitis and dandruff with 2% ketoconazole shampoo: results of a multicentre, double-blind, placebo-controlled trial. Br J Dermatol. 1995;132:441–5.

    Article  CAS  PubMed  Google Scholar 

  • Piérard GE. Seborrheic dermatitis today, gone tomorrow? The link between the biocene and treatment. Dermatology. 2003;206:187–8.

    Article  PubMed  Google Scholar 

  • Pierard-Franchimont C, Goffin V, Decroix J, Pierard GE. A multicenter randomized trial of ketoconazole 2% and zinc pyrithione 1% shampoos in severe dandruff and seborrheic dermatitis. Skin Pharmacol Appl Skin Physiol. 2002;15:434–41.

    Article  CAS  PubMed  Google Scholar 

  • Pirkhammer D, Seeber A, Hönigsmann H, Tanew A. Narrow-band ultraviolet B (ATL-01) phototherapy is an effective and safe treatment option for patients with severe seborrhoeic dermatitis. Br J Dermatol. 2000;143:964–8.

    Article  CAS  PubMed  Google Scholar 

  • Ratnavel RC, Squire RA, Boorman GC. Clinical efficacies of shampoos containing ciclopiroxolamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis. J Dermatol Treat. 2007;18:88–96.

    Article  CAS  Google Scholar 

  • Scaparro E, Quadri G, Virno G, Orifici C, Milani M. Evaluation of the efficacy and tolerability of oral terbinafine (Daskil®) in patients with seborrheic dermatitis. A multicentre, randomized, investigator blinded, placebo-controlled trial. Br J Dermatol. 2001;144:854–7.

    Article  CAS  PubMed  Google Scholar 

  • Stratigos JD, Antoniou C, Katsambas A, Böhler K, Fritsch P, Schmöl A, et al. Ketoconazole 2% cream versus hydrocortisone 1% cream in the treatment of seborrheic dermatitis: a double-blind comparative study. J Am Acad Dermatol. 1988;19:850–3.

    Article  CAS  PubMed  Google Scholar 

  • Warshaw EM, Wohlhuter RJ, Liu A, Zeller SA, Wenner RA, Bowers S, et al. Results of a randomized, double-blind, vehicle-controlled efficacy trial of pimecrolimus cream 1% for the treatment of moderate to severe facial seborrheic dermatitis. J Am Acad Dermatol. 2007;57:257–64.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohamad Goldust .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Goldust, M., Gupta, M. (2023). Seborrhoeic Dermatitis. In: Katsambas, A.D., Lotti, T.M., Dessinioti, C., D'Erme, A.M. (eds) European Handbook of Dermatological Treatments. Springer, Cham. https://doi.org/10.1007/978-3-031-15130-9_86

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-15130-9_86

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-15129-3

  • Online ISBN: 978-3-031-15130-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics