Skip to main content
SpringerLink
Log in

Holy Cow! (“I’m Bloodless”)

  • Chapter
  • First Online:
Immunohematology, Transfusion Medicine, Hemostasis, and Cellular Therapy

  • 524 Accesses

Abstract

Management of the anemic patient who will not accept a transfusion of blood products can be quite challenging. Knowledge of treatment strategies and alternative treatments is key to providing effective care for such patients. Solve it!

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Spahn DR. Blood substitutes artificial oxygen carriers: perfluorocarbon emulsions. Crit Care. 1999;3(5):R93–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Greenburg AG, Kim HW. Hemoglobin-based oxygen carriers. Crit Care. 2004;8(Suppl 2):S61–4.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Alayash A. Hemoglobin-based blood substitutes and the treatment of sickle cell disease: more harm than help? Biomol Ther. 2017;7(4):2. Bahler J, editor.

    Google Scholar 

  4. Chen J-Y, Scerbo M, Kramer GA. Review of blood substitutes: examining the history, clinical trial results, and ethics of hemoglobin-based oxygen carriers. Clinics. 2009;64(8):803–13.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Abuchowski A. PEGylated bovine carboxyhemoglobin (SANGUINATE™): results of clinical safety testing and use in patients. Adv Expo Med Biol. 2016;876:461–7.

    Article  CAS  Google Scholar 

  6. Henriques C. Prolong completes enrolling patients in phase 2 trial of sickle cell disease therapy Sanguinate. In: Sickle cell anemia news. 21 Dec 2017. https://sicklecellanemianews.com/2017/12/21/prolong-completes-enrollment-in-phase-2-trial-of-sickle-cell-disease-therapy-sanguinate/. Accessed 28 Feb 2022.

Further Reading

  • Simoni J, Simoni G, Moeller JF. Intrinsic toxicity of hemoglobin: how to counter act it. Artif Organs. 2009;33(2):100–9.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, NYU Lagone Health, Mineola, NY, USA

    Mark T. Friedman

  2. Department of Transfusion Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA

    Kamille A. West

  3. Department of Pediatrics, Northwell Health System, Great Neck, NY, USA

    Peyman Bizargity

  4. Department of Pathology, Children’s Hospital Colorado, Aurora, CO, USA

    Kyle Annen

  5. Department of Pathology, Northwell Health System, Greenvale, NY, USA

    H. Deniz Gur

  6. Department of Pathology, NYU Langone Health, New York, NY, USA

    Timothy Hilbert

Authors
  1. Mark T. Friedman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kamille A. West
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Peyman Bizargity
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kyle Annen
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. Deniz Gur
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Timothy Hilbert
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Mark T. Friedman .

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Friedman, M.T., West, K.A., Bizargity, P., Annen, K., Gur, H.D., Hilbert, T. (2023). Holy Cow! (“I’m Bloodless”). In: Immunohematology, Transfusion Medicine, Hemostasis, and Cellular Therapy. Springer, Cham. https://doi.org/10.1007/978-3-031-14638-1_70

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-14638-1_70

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-14637-4

  • Online ISBN: 978-3-031-14638-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation