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Respiratory Physiology and Mechanics at the Bedside

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Personalized Mechanical Ventilation

Abstract

Understanding the different mechanics of breathing and applying personalized management that matches the patient physiologic parameters and considers the available technology are of paramount importance for all ventilated patients. Pressures and flows are two ways to express lung function in respiratory mechanics. These measurements can be used to derive a variety of indices, such as volume, compliance, resistance, and work of breathing. Plateau pressure is an indicator of the pressure at the end of the inspiration. More and more researchers are realizing that end-inspiratory transpulmonary pressure (stress) might be a better indicator of lung injury than plateau pressure alone. Esophageal manometry has become increasingly popular in mechanically ventilated patients as a result. In addition to the end-expiratory transpulmonary pressure, PEEP might also be used as a guide to help counterbalance the collapse of the alveoli. The shape of the pressure-time curve might also be useful to guide the setting of PEEP.

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Change history

  • 11 January 2023

    The affiliation of first author Ahmed Mohamed Reda Taha was incorrectly printed in Chapter 1 (Respiratory Physiology and Mechanics at the Bedside) as Intensive Care and COVID 19 Unit, Belize Healthcare Partners, Belize, Belize. It has now been corrected to “Critical Care Institute, Cleveland Clinic, Abu Dhabi, UAE” on pages iv and 1.

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Author information

Authors and Affiliations

  1. Critical Care Institute, Cleveland Clinic, Abu Dhabi, UAE

    Ahmed Mohamed Reda Taha

  2. NMC Specialty, Dubai, UAE

    Prashant Nasa

Authors
  1. Ahmed Mohamed Reda Taha
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  2. Prashant Nasa
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Editor information

Editors and Affiliations

  1. Critical Care Division Belize Healthcare Partners, Belize, Belize

    Jorge Hidalgo

  2. Pulmonary and Critical Care, University of Michigan, Ann Arbor, MI, USA

    Robert C Hyzy

  3. Critical Care Institute, Cleveland Clinic, Abu Dhabi, United Arab Emirates

    Ahmed Mohamed Reda Taha

  4. Critical Care, King Faisal Specialist Hospital & Research, Riyadh, Saudi Arabia

    Yasser Younis A. Tolba

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Mohamed Reda Taha, A., Nasa, P. (2022). Respiratory Physiology and Mechanics at the Bedside. In: Hidalgo, J., Hyzy, R.C., Mohamed Reda Taha, A., Tolba, Y.Y.A. (eds) Personalized Mechanical Ventilation . Springer, Cham. https://doi.org/10.1007/978-3-031-14138-6_1

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  • DOI: https://doi.org/10.1007/978-3-031-14138-6_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-14137-9

  • Online ISBN: 978-3-031-14138-6

  • eBook Packages: MedicineMedicine (R0)

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