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Failed Allograft Due to Persistent BKV

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Complications in Kidney Transplantation

Abstract

BK virus nephropathy (BKVN) is an opportunistic infection in the post-kidney transplantation period with a prevalence of up to 3–5% [1]. It can lead to allograft dysfunction, ureteral strictures, de novo DSA due to the reduction of immunosuppression, graft rejection, and rarely urological malignancies. The net state of immunosuppression is the most important risk factor for BKVN, and there is a higher risk with the use of anti-thymocyte globulin (ATG) and mycophenolate mofetil (MMF) or tacrolimus [2]. Prior allograft loss attributed to BKVN is not a contraindication for re-transplantation [3, 4]. We will explore some of the considerations in retransplantation amongst this patient population.

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Correspondence to Bushra Syed .

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Sriperumbuduri, S., Syed, B. (2022). Failed Allograft Due to Persistent BKV. In: Aziz, F., Parajuli, S. (eds) Complications in Kidney Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-031-13569-9_66

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  • DOI: https://doi.org/10.1007/978-3-031-13569-9_66

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-13568-2

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