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Complications in Kidney Transplantation pp 249–254Cite as

Post-Transplant Idiopathic Immune Complex Glomerulonephritis

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Abstract

Membranoproliferative Glomerulonephritis (MPGN) is one of the important causes of end-stage kidney disease (ESKD), leading to kidney transplants. Moreover, the occurrence of MPGN in kidney allograft negatively impacts its survival. The reclassification of MPGN with immunofluorescence has transformed the way we diagnose and treat the condition in kidney transplant recipients. The optimal treatment of post-transplant idiopathic immune complex-mediated MPGN (IC-MPGN) is not established. In this chapter, we have attempted to highlight a classic case of de novo idiopathic IC-MPGN in a kidney allograft recipient. He achieved successful remission with rituximab and appropriate up-titration of immunosuppression.

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Authors and Affiliations

  1. Department of Medicine, University of Wisconsin—Madison School of Medicine and Public Health, University of Wisconsin Hospital and Clinics, Madison, WI, USA

    Keshvi Chauhan & Fahad Aziz

Authors
  1. Keshvi Chauhan
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  2. Fahad Aziz
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Correspondence to Keshvi Chauhan .

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Editors and Affiliations

  1. University of Wisconsin, Madison, WI, USA

    Fahad Aziz

  2. Department of Medicine, University of Wisconsin, Madison, WI, USA

    Sandesh Parajuli

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Chauhan, K., Aziz, F. (2022). Post-Transplant Idiopathic Immune Complex Glomerulonephritis. In: Aziz, F., Parajuli, S. (eds) Complications in Kidney Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-031-13569-9_40

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  • DOI: https://doi.org/10.1007/978-3-031-13569-9_40

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-13568-2

  • Online ISBN: 978-3-031-13569-9

  • eBook Packages: MedicineMedicine (R0)

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