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Benjamin D. Sachs

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Biographical History of Behavioral Neuroendocrinology
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Abstract

Ben Sachs is one of the world’s experts on the neuroendocrine mechanisms that control sexual arousal, penile erectile function, and the expression of mating behavior in male rodents. His research laboratory produced experimental work on the respective roles of testosterone and/or its neural metabolite estradiol, acting perinatally to organize circuits that control male reproductive behaviors in adult male rats and acting postpubertally to activate these same circuits and the resultant expression of reproductive behaviors. Sachs was a master at integrating experimental animal and human clinical research findings in numerous review papers published over the course of his career that advanced our understanding of how hormones act in the brain to control male reproductive behaviors. He was also a generous mentor and friend to numerous students, postdoctoral fellows, and academic colleagues from around the world (including the two authors of this biographical sketch).

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References

  • Barfield, R. J., & Sachs, B. D. (1968). Sexual behavior: Stimulation by painful electrical shock to skin in male rats. Science, 161, 392–395.

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  • Baum, M. J. (2009). Sexual differentiation of pheromone processing: Links to male-typical mating behavior and partner preference. Hormones and Behavior, 55, 579–588.

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  • Emery, D. E., & Sachs, B. D. (1975). Ejaculatory pattern in female rats without androgen treatment. Science, 190, 484–486.

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  • Emery, D. E., & Sachs, B. D. (1976). Copulatory behavior in male rats with lesions in the bed nucleus of the stria terminalis. Physiology & Behavior, 17, 803–806.

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  • Harris, V. S., & Sachs, B. D. (1975). Copulatory behavior in male rats following amygdaloid lesions. Brain Research, 86, 514–518.

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  • Sachs, B. D. (1978). Conceptual and neural mechanisms of masculine copulatory behavior. In T. E. McGill, D. A. Dewsbury, & B. D. Sachs (Eds.), Sex and behavior: Status and prospectus (pp. 267–295). Plenum Press.

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  • Sachs, B. D. (2003). The false organic-psychogenic distinction and related problems in the classification of erectile dysfunction. International Journal of Impotence Research, 15, 72–78.

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  • Sachs, B. D., & Harris, V. S. (1978). Sex differences and developmental changes in selected juvenile activities (play) of domestic lambs. Animal Behaviour, 26, 678–684.

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  • Sachs, B. D., & Meisel, R. L. (1988). The physiology of male sexual behavior. In E. Knobil & J. D. Neill (Eds.), The physiology of reproduction (Vol. 2, pp. 1393–1485). Raven Press.

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  • Thornton, J., Zehr, J. L., & Loose, M. D. (2009). Effects of prenatal androgens on rhesus monkeys: A model system to explore the organizational hypothesis in primates. Hormones and Behavior, 55, 633–645.

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Correspondence to Robert L. Meisel .

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Meisel, R.L., Baum, M.J. (2022). Benjamin D. Sachs. In: Nelson, R.J., Weil, Z.M. (eds) Biographical History of Behavioral Neuroendocrinology . Springer, Cham. https://doi.org/10.1007/978-3-031-12970-4_18

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