Abstract
Allergen immunotherapy is a cornerstone of therapy for the practice of allergy and immunology. It is important to understand the selection of patients, indications, and contraindications for immunotherapy. It is also increasingly important to recognize similarities and differences between subcutaneous and sublingual immunotherapy. Developing the knowledge of the risks and benefits of immunotherapy is central to effectively engage patients in shared decision-making. When initiating immunotherapy, it is essential to gain expertise in the selection of appropriate antigens and to utilize them in effective doses and combinations. Familiarity with dosing schedules, intervals and duration can improve the likelihood of safe and effective therapy.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Bibliography
National Asthma Education and Prevention Program. Third Expert Panel on the Diagnosis and Management of Asthma. Expert panel report 3: guidelines for the diagnosis and management of asthma. Bethesda, MD: National Heart, Lung, and Blood Institute (US); 2007. 440 pp. https://www.ncbi.nlm.nih.gov/books/NBK7232/.
National Asthma Education and Prevention Program. 2020 Focused updates to the ashtma management guidelines. Bethesda, MD: National Heart, Lung, and Blood Institute (US); 2020. https://www.nhlbi.nih.gov/health-topics/all-publications-and-resources/2020-focused-updates-asthma-management-guidelines.
Cox L, Nelson H, Lockey R, Calabria C, Chacko T, Finegold I, et al. Allergen immunotherapy: a practice parameter third update. J Allergy Clin Immunol. 2011;127(1 Suppl):S1–S55.
Calderon MA, Waserman S, Bernstein DI, Demoly P, Douglass J, Gagnon R, et al. Clinical practice of allergen immunotherapy for allergic rhinoconjunctivitis and asthma: an expert panel report. J Allergy Clin Immunol Pract. 2020;8:2920–36.
Greenhawt M, Oppenheimer J, Nelson M, Nelson H, Lockey R, Lieberman P, et al. Sublingual immunotherapy: a focused allergen immunotherapy practice parameter update. Ann Allergy Asthma Immunol. 2017;118:276–82.
Dykewicz MS, Wallace DV, Amrol DJ, Baroody FM, Bernstein JA, et al. Rhinitis 2020: a practice parameter update. J Allergy Clin Immunol. 2020;146:721–67.
Roberts G, Pfaar O, Akdis CA, Ansotegui IJ, Durham SR, Gerth van Wijk R, et al. EAACI guidelines on allergen immunotherapy: allergic rhinoconjunctivitis. Allergy. 2018;73:765–98.
Schneider L, Tilles S, Lio P, Boguniewicz M, Beck L, LeBovidge J, et al. Atopic dermatitis: a practice parameter update 2012. Allergy Clin Immunol. 2013;131:295–9.
Sampson HA, Aceves S, Bock SA, James J, Jones S, Lang D, et al. Food allergy: a practice parameter update—2014. J Allergy Clin Immunol. 2014;134:1016–25.
Bernstein JA, Lang DM, Khan DA, Craig T, Dreyfus D, Hsieh F, et al. The diagnosis and management of acute and chronic urticaria: 2014 update. J Allergy Clin Immunol. 2014;133:1270–7.
Turkeltaub PC, Rastogi SC, Baer H, Anderson MC, Norman PS. A standardized quantitative skin-test assay of allergen potency and stability: studies on the allergen dose-response curve and effect of wheal, erythema, and patient selection on assay results. J Allergy Clin Immunol. 1982;70(5):343–52.
Golden DB, Demain J, Freeman T, Graft D, Tankersley M, Tracy J, et al. Stinging insect hypersensitivity: a practice parameter update 2016. Ann Allergy Asthma Immunol. 2017;118(1):28–54.
Cox L. Advantages and disadvantages of accelerated immunotherapy schedules. J Allergy Clin Immunol. 2008;122(2):432–4.
Schiavino D, Nucera E, Pollastrini E, De Pasquale T, Buonomo A, Bartolozzi F, et al. Specific ultrarush desensitization in Hymenoptera venom-allergic patients. Ann Allergy Asthma Immunol. 2004;92(4):409–13.
Wesley Burks M, Holgate ST, O’Hehir RE, Bacharier LB, Broide DH, Khurana Hershey GK, Peebles S. Middleton’s allergy: principles and practice, 2 vols. Philadelphia: Elsevier; 2019. 1840 p.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Adams, K.E., Quinn, J.M. (2022). Allergen Immunotherapy. In: Mahmoudi, M. (eds) Absolute Allergy and Immunology Board Review. Springer, Cham. https://doi.org/10.1007/978-3-031-12867-7_31
Download citation
DOI: https://doi.org/10.1007/978-3-031-12867-7_31
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-12866-0
Online ISBN: 978-3-031-12867-7
eBook Packages: MedicineMedicine (R0)