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Quantitative T1ρ MR Imaging in Neuroradiology

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Functional Neuroradiology

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Abstract

The objective of this chapter is to briefly review the physics of T1ρ(rho) magnetic resonance (MR) imaging and to focus on potential applications in neuroradiology by reviewing recent published work at both 1.5 T and 3.0 T. Normative values for T1ρ have been quantified across adulthood demonstrating age dependence. A number of studies have explored its use in degenerative disc disease as an indirect marker of proteoglycan content within intervertebral discs on lumbar spine MR imaging. In brain MR imaging, there is ongoing research in the use of T1ρ in neurodegenerative disease, demyelinating disease, stroke, and neoplasm.

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Authors and Affiliations

  1. Department of Radiology, Tufts Medical Center and Tufts University School of Medicine, Boston, MA, USA

    Christopher G. Filippi

  2. Department of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra-Northwell, Hempstead, NY, USA

    Alexander Klebba

  3. Department of Radiology, Lenox Hill Hospital, New York, NY, USA

    Alexander Klebba

  4. Department of Radiology, Robert Larner School of Medicine University of Vermont, Burlington, VT, USA

    Scott Hipko

  5. Department of Psychology, Yale University School of Medicine, New Haven, CT, USA

    Richard Watts

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  1. Christopher G. Filippi
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Editors and Affiliations

  1. Division of Neuroradiology, Thomas Jefferson University, Philadelphia, PA, USA

    Scott H. Faro

  2. Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USA

    Feroze B. Mohamed

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Filippi, C.G., Klebba, A., Hipko, S., Watts, R. (2023). Quantitative T1ρ MR Imaging in Neuroradiology. In: Faro, S.H., Mohamed, F.B. (eds) Functional Neuroradiology. Springer, Cham. https://doi.org/10.1007/978-3-031-10909-6_56

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