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Child with Global Developmental Delay

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Symptom-Based Approach to Pediatric Neurology

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Abstract

Global developmental delay (GDD) is a common finding in the pediatric population and is found in 1–3% of children under the age of 5 years. GDD is etiologically diverse. A comprehensive assessment with thorough history and physical examination can help determine the next best diagnostic steps for evaluating these patients. Up to 25–50% of children with GDD will have an identified genetic etiology. Specific guidelines exist for recommended genetic testing in this population, though these are likely to change with recent advances in genetic medicine. Early diagnosis of GDD and identification of the specific etiology can help improve outcomes in many cases, allowing for earlier therapeutic intervention and identifying other associated health issues that may be subsequently managed.

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Author information

Authors and Affiliations

  1. Division of Genetic, Genomic and Metabolic Disorders, Children’s Hospital of Michigan, Detroit, MI, USA

    Leigh Anne Flore

  2. Central Michigan University, College of Medicine, Mt. Pleasant, MI, USA

    Leigh Anne Flore

  3. Division of Genetic, Genomic and Metabolic Disorders, Detroit Medical Center/Wayne State University, Detroit, MI, USA

    Stephanie Campbell

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  1. Leigh Anne Flore
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Correspondence to Leigh Anne Flore .

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Editors and Affiliations

  1. Department of Pediatrics, University of Texas Health Science Center, San Antonio, TX, USA

    Deepak M. Kamat

  2. Pediatrics and Neurology, Central Michigan University Children’s Hospital of Michigan, Detroit, MI, USA

    Lalitha Sivaswamy

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Flore, L.A., Campbell, S. (2022). Child with Global Developmental Delay. In: Kamat, D.M., Sivaswamy, L. (eds) Symptom-Based Approach to Pediatric Neurology . Springer, Cham. https://doi.org/10.1007/978-3-031-10494-7_3

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  • DOI: https://doi.org/10.1007/978-3-031-10494-7_3

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  • Online ISBN: 978-3-031-10494-7

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