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18F-Flubrobenguane

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PET Radiopharmaceuticals

Part of the book series: Clinicians’ Guides to Radionuclide Hybrid Imaging ((PET/CT))

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Abstract

Flubrobenguane is used for imaging myocardial sympathetic innervation for risk stratification in heart failure.

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Further Reading

  • Sinusas AJ, Lazewatsky J, Brunetti J, et al. Biodistribution and radiation dosimetry of LMI1195: first-in-human study of a novel 18F-labeled tracer for imaging myocardial innervation. J Nucl Med. 2014;55:1445–51.

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  • Yu M, Bozek J, Lamoy M, et al. Evaluation of LMI1195, a novel 18F-labeled cardiac neuronal PET imaging agent, in cells and animal models. Circ Cardiovasc Imaging. 2011;4:435–43.

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  • Yu M, Bozek J, Lamoy M, et al. LMI1195 PET imaging in evaluation of regional cardiac sympathetic denervation and its potential role in antiarrhythmic drug treatment. Eur J Nucl Med Mol Imaging. 2012;39:1910–9.

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  • Zelt JG, Britt D, Mair BA, et al. Regional distribution of fluorine-18-flubrobenguane and carbon-11-hydroxyephedrine for cardiac PET imaging of sympathetic innervation. JACC Cardiovasc Imaging. 2021;14:1425–36.

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  • Zelt JG, Mielniczuk LM, Orlandi C, et al. PET imaging of sympathetic innervation with [18F]flubrobenguane vs [11C]mHED in a patient with ischemic cardiomyopathy. J Nucl Cardiol. 2019;26:2151–3.

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Authors and Affiliations

  1. School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK

    James R. Ballinger

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  1. James R. Ballinger
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Correspondence to James R. Ballinger .

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© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Ballinger, J.R. (2022). 18F-Flubrobenguane. In: PET Radiopharmaceuticals. Clinicians’ Guides to Radionuclide Hybrid Imaging(). Springer, Cham. https://doi.org/10.1007/978-3-031-10271-4_39

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  • DOI: https://doi.org/10.1007/978-3-031-10271-4_39

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-10270-7

  • Online ISBN: 978-3-031-10271-4

  • eBook Packages: MedicineMedicine (R0)

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