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Acute Liver Failure

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Liver Disease in Clinical Practice

Part of the book series: In Clinical Practice ((ICP))

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Abstract

The modern management of acute liver failure has been associated with a significant improvement in outcomes over the past decades. High quality care requires clinicians to be able to recognise and diagnose the syndrome, offer prompt focused resuscitation and refer early to regional liver failure centres. Critically unwell patients, particularly those with hyperacute liver failure, require early management in a critical care setting with particular attention to fluid resuscitation, cardiovascular and metabolic support. The focus on prophylaxis of cerebral oedema, as described in this chapter, has significantly reduced death from raised intracranial pressure. Early recognition of patients meeting poor prognostic criteria will facilitate referral to specialist centres and assessment for liver transplantation or other specialist therapies.

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Correspondence to Brian J. Hogan .

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Packer, G., Hogan, B.J. (2022). Acute Liver Failure. In: Cross, T. (eds) Liver Disease in Clinical Practice. In Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-031-10012-3_2

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  • DOI: https://doi.org/10.1007/978-3-031-10012-3_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-10011-6

  • Online ISBN: 978-3-031-10012-3

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