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Assessment of Liver Function

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Liver Disease in Clinical Practice

Part of the book series: In Clinical Practice ((ICP))

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The liver is the largest solid organ in the human body. It performs key roles in glucose metabolism, lipid metabolism, synthesis of proteins and clotting factors, storage of vitamins and immune regulation. In contrast to other organs the blood supply to the liver is predominantly venous (70–75%). The liver function tests can help to elicit the cause of liver disease, i.e., pre-hepatic, hepatic or post-hepatic. The degree of liver scarring (fibrosis) historically was determined by liver biopsy, but non-invasive tests are now available for routine clinical use. The most common causes of abnormal LFTs are related to alcohol, fatty liver disease and medication. History and clinical examination are vital to investigating abnormal liver function.

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Correspondence to Cyril Sieberhagen .

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Papamargaritis, I., Sieberhagen, C. (2022). Assessment of Liver Function. In: Cross, T. (eds) Liver Disease in Clinical Practice. In Clinical Practice. Springer, Cham.

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-10011-6

  • Online ISBN: 978-3-031-10012-3

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