Abstract
Here we present a 25-year-old woman with pruritic and bullous lesions on the skin developed 5 days after the delivery. Histopathologic findings in biopsy of urticarial lesions were characterized by edema of the epidermis, upper and mid-dermis with a perivascular infiltrate by lymphocytes, histiocytes, and eosinophils. Direct immunofluorescence showed C3 and IgG deposition at the basement membrane zone, and enzyme-linked immunosorbent assay (ELISA) showed circulating IgG autoantibodies against BP180. This disorder can mimic polymorphic eruption of pregnancy, herpes associated erythema multiforme, intrahepatic cholestasis of pregnancy (ICP), atopic eruption of pregnancy (AEP) and should be confirmed by histological method, direct and indirect immunofluorescence, or ELISA.
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Olisova, O., Teplyuk, N.P., Lepekhova, A.A., Varshavsky, V. (2022). A 25-Year-Old Woman with the Pruritic and Bullous Lesions on the Skin Developed in the Third Trimester of Pregnancy 3 Days Before the Delivery. In: Lotti, T.M., Wollina, U., Olisova, O., Jafferany, M. (eds) Clinical Cases in Exfoliative Dermatitis. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-031-08466-9_1
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DOI: https://doi.org/10.1007/978-3-031-08466-9_1
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