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Neoplastic Lesions of the Tongue

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Tongue Lesions

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Abstract

As shown in Table 10.1, tongue neoplasms (tumors), whether benign or malignant, are classified according to tissue of origin into epithelial tumors, mesenchymal tumors, and tumors of salivary gland or thyroid gland origin.

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References

  1. Bouquot JE, Nikai H. Lesions of the oral cavity. In: Gnepp DR, editor. Diagnostic surgical pathology of the head and neck. Philadelphia: Saunders; 2001. p. 141.

    Google Scholar 

  2. Gardner ES, Goldberg LH. Granular cell tumor treated with Mohs micrographic surgery: report of a case and review of the literature. Dermatol Surg. 2001;27(8):772–4.

    CAS  PubMed  Google Scholar 

  3. Mooney MA, Janniger CK. Pyogenic granuloma. Cutis. 1995;55(3):133–6.

    CAS  PubMed  Google Scholar 

  4. Castro TMPPG, Filho IB. Prevalence of human papillomavirus (HPV) in oral cavity and oropharynx. Braz J Otorhinolaryngol. 2006;72(2):272–82.

    Article  PubMed  Google Scholar 

  5. Castro TMPPG, Neto CER, Scala KA, et al. Oral manifestations related to papillomavirus. Braz J Otorhinolaryngol. 2004;70(4):546–50.

    Google Scholar 

  6. Jaju PP, Suvarna PV, Desai RS. Squamous papilloma: case report and review of literature. Int J Oral Sci. 2010;2(4):222–5.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Carneiro TE, Marinho SA, Verli FD, et al. Oral squamous papilloma: clinical, histologic and immunohistocheamecal analyses. J Oral Sci. 2009;51(3):367–72.

    Article  PubMed  Google Scholar 

  8. Mannarini L, Kratochivil V, Calabrese L, et al. Human papilloma virus (HPV) in head and neck region: review of literature. Acta Otorhinolaryngol Ital. 2009;29:119–26.

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Williams JD, Sclafani AP, Slupchinskij O, Douge C. Evaluation and management of the lingual thyroid gland. Ann Otol Rhinol Laryngol. 1996;105(4):312–6.

    Article  CAS  PubMed  Google Scholar 

  10. Kansal P, Sakati N, Rifai A, Woodhouse N. Lingual thyroid. Diagnosis and treatment. Arch Intern Med. 1987;147(11):2046–8.

    Article  CAS  PubMed  Google Scholar 

  11. Taibah K, Ahmed M, Baessa E, Saleem M, Rifai A, al-Arifi A. An unusual cause of obstructive sleep apnoea presenting during pregnancy. J Laryngol Otol. 1998;112(12):1189–91.

    Article  CAS  PubMed  Google Scholar 

  12. Neville BW, Damm DD, Allen CM. Oral and maxillofacial pathology. 2nd ed. Philadelphia: WB Saunders; 2002.

    Google Scholar 

  13. Avila ED, Molon RS, Conte Neto N, Gabrielli MA, Hochuli-Vieira E. Lip cavernous hemangioma in a young child. Braz Dent J. 2010;21:370–4.

    Article  PubMed  Google Scholar 

  14. Okoji VN, Alonge TO, Olusanya AA. Intra-tumoral ligation and the injection of sclerosant in the treatment of lingual cavernous hemangioma. Niger J Med. 2011;20:172–5.

    Google Scholar 

  15. Sakoda S, Kodama Y, Shiba R. Lymphoepithelial cyst of oral cavity. Report of a case and review of the literature. Int J Oral Surg. 1983;12(2):127–31.

    Article  CAS  PubMed  Google Scholar 

  16. Llewellyn CD, Johnson NW, Warnakulasuriya KA. Risk factors for squamous cell carcinoma of the oral cavity in young people - a comprehensive literature review. Oral Oncol. 2001;37(5):401–18.

    Article  CAS  PubMed  Google Scholar 

  17. Sherin N, Simi T, Shameena P, Sudha S. Changing trends in oral cancer. Indian J Cancer. 2008;45(3):93–6.

    Article  CAS  PubMed  Google Scholar 

  18. Jones AS, Rafferty M, Fenton JE, Jones TM, Husband DJ. Treatment of squamous cell carcinoma of the tongue base: irradiation, surgery, or palliation? Ann Otol Rhinol Laryngol. 2007;116(2):92–9.

    Article  PubMed  Google Scholar 

  19. Ordonez NG, Mackay B. Alveolar soft-part sarcoma: a review of the pathology and histogenesis. Ultrastruct Pathol. 1998;22:275–92.

    Article  CAS  PubMed  Google Scholar 

  20. Lorigan JG, O’Keeffe FN, Evans HL, Wallace S. The radiologic manifestations of alveolar soft-part sarcoma. AJR Am J Roentgenol. 1989;153:335–9.

    Article  CAS  PubMed  Google Scholar 

  21. Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 1982;69:412–20.

    Article  CAS  PubMed  Google Scholar 

  22. Donald PJ. Alveolar soft part sarcoma of the tongue. Head Neck Surg. 1987;9:172–8.

    Article  CAS  PubMed  Google Scholar 

  23. Iwamoto Y, Morimoto N, Chuman H, et al. The role of MR imaging in the diagnosis of alveolar soft part sarcoma: a report of 10 cases. Skelet Radiol. 1995;24:267–70.

    Article  CAS  Google Scholar 

  24. Hunter BC, Ferlito A, Devaney KO, Rinaldo A. Clinicopathological consultation: alveolar soft part sarcoma of the head and neck region. Ann Otol Rhinol Laryngol. 1998;107:810–4.

    Article  CAS  PubMed  Google Scholar 

  25. Ordónez NG. Alveolar soft part sarcoma: a review and update. Adv Anat Pathol. 1999;6:125–39.

    Article  PubMed  Google Scholar 

  26. Aiken AH, Jeffrey A. Stone alveolar soft-part sarcoma of the tongue. Case report. AJNR Am J Neuroradiol. 2003;24:1156–8.

    PubMed  PubMed Central  Google Scholar 

  27. Al-Daraji W, Lasota J, Foss R, Miettinen M. Synovial sarcoma involving the head: analysis of 36 cases with predilection to the parotid and temporal regions. Am J Surg Pathol. 2009;33(10):1494–503.

    Article  PubMed  Google Scholar 

  28. Engelhardt J, Leafstedt SW. Synovial sarcoma of tonsil and tongue base. Case Rep Dermatol. 1983;76(2):243–4.

    CAS  Google Scholar 

  29. Fortuño-Mar A, Mayayo E, Guiral H, et al. Synovial sarcoma of the tongue: case report and review of the literature. An Otorrinolaringol Ibero Am. 2000;27(4):323–31.

    PubMed  Google Scholar 

  30. Carrillo R, El-Naggar AK, Rodriguez-Peralto JL, Batsakis JG. Synovial sarcoma of the tongue: case report and review of the literature. J Oral Maxillofac Surg. 1992;50(8):904–6.

    Article  CAS  PubMed  Google Scholar 

  31. Ghodsi S, Sadr AM, Moussavi A. Synovial sarcoma of the tongue: report of a case. Acta Med Iran. 1974;17(3-4):155–60.

    CAS  PubMed  Google Scholar 

  32. Guzman PC, Ortiz TH, Garza GR. Synovial sarcoma of the oral cavity (foramen caecum): report of a case and review of the literature. Prensa Med Mex. 1975;19:215–20.

    Google Scholar 

  33. Holtz F, Magielski JE. Synovial sarcomas of the tongue base: the seventh reported case. Arch Otolaryngol. 1985;111(4):271–2.

    Article  CAS  PubMed  Google Scholar 

  34. Bridge JA, Bridge RS, Borek DA, et al. Translocation t(X; 18) in orofacial synovial sarcoma. Cancer. 2015;62:935–7.

    Article  Google Scholar 

  35. Komis C, Lagogiannis GA, Faratzis G, Rapidis AD. Synovial sarcoma of the tongue: report of a case and review of the literature. J Oral Maxillofac Surg. 2008;66:154–60.

    Article  PubMed  Google Scholar 

  36. Novotny GM, Fort TC. Synovial sarcoma of the tongue. Arch Otolaryngol. 1971;94(1):77–9.

    Article  CAS  PubMed  Google Scholar 

  37. Shmookler BM, Enzinger FM, Brannon RB. Orofacial synovial sarcoma: a clinicopathologic study of 11 new cases and review of the literature. Cancer. 1982;50(2):269–76.

    Article  CAS  PubMed  Google Scholar 

  38. Murphey MD, Smith WS, Smith SE, et al. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation. Radiographics. 1999;19:1253–80.

    Article  CAS  PubMed  Google Scholar 

  39. Hirsch RJ, Yousem DM, Loevner LA, et al. Synovial sarcomas of the head and neck: MR findings. Am J Roentgenol. 1997;169(4):1185–8.

    Article  CAS  Google Scholar 

  40. Villaroel-Salinas J, Campos-Martinez J, Ortiz-Hidalgo C. Synovial sarcoma of the tongue confirmed by molecular detection of the SYT-SSX2 fusion gene transcript. Int J Surg Pathol. 2012;20:386–9.

    Article  PubMed  Google Scholar 

  41. Olsen SH, Thomas DG, Lucas DR. Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma. Mod Pathol. 2006;19:659–68.

    Article  CAS  PubMed  Google Scholar 

  42. Naka N, Takenaka S, Araki N, Toshitada M, Nobuyuki H, Kiyoko Y. Synovial sarcoma is a stem cell malignancy. Stem Cells. 2010;28(7):1119–31.

    Article  CAS  PubMed  Google Scholar 

  43. Basile LE, Hoch B, Dillon JK. Synovial sarcoma of the tongue: report of a case. J Oral Maxillofac Surg. 2016;74(1):95–103.

    Article  PubMed  Google Scholar 

  44. Lagrange JL, Ramaioli A, Chateau MC, Marchal C, Resbeut M, Richaud R, et al. Sarcoma after radiation therapy: retrospective multiinstitutional study of 80 histologically confirmed cases. Radiology. 2000;216(1):197–205.

    Article  CAS  PubMed  Google Scholar 

  45. Agarwal AP, Shet TM, Joshi R, Desai SB, Chinoy RF, et al. Monophasic synovial sarcoma of tongue. Indian J Pathol Microbiol. 2009;52:568–70.

    Article  PubMed  Google Scholar 

  46. Bilgic B, Mete Ö, Öztürk AS, Demiryont M, Keles N, Basaran M. Synovial sarcoma: a rare tumor of larynx. Pathol Oncol Res. 2003;9:242–5.

    Article  PubMed  Google Scholar 

  47. Fayda M, Aksu G, Agaoglu FY, Karadeniz A, Darendeliler E, Altun M, et al. The role of surgery and radiotherapy in treatment of soft tissue sarcomas of the head and neck region: review of 30 cases. J Craniomaxillofac Surg. 2009;37(1):42–8.

    Article  PubMed  Google Scholar 

  48. Yang JC, Chang AE, Baker AR, Sindelar WF, Danforth DN, Topalian SL, et al. Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. J Clin Oncol. 1998;16(1):197–203.

    Article  CAS  PubMed  Google Scholar 

  49. National Comprehensive Cancer Network, version 2.2017. Fort Washington: NCCN, 2017.

    Google Scholar 

  50. Meer S, Coleman H, Altini M. Oral synovial sarcoma: a report of 2 cases and a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;96(3):306–15.

    Article  PubMed  Google Scholar 

  51. Su Z, Zhang J, Gao P, Shi J, Qi M, Chen L, Wang X. Synovial sarcoma of the tongue: report of a case and review of the literature. Ann R Coll Surg Engl. 2018;100(5):118–22.

    Article  Google Scholar 

  52. Saito T, Mitomi H, Kurisaki A, Torigoe T, Takagi T, Suehara Y, et al. Low-grade myofibroblastic sarcoma of the distal femur. Int J Surg Case Rep. 2013;4:195–9.

    Article  PubMed  Google Scholar 

  53. Roth TM, Fratkin J, Woodring TC, McGehee RP. Low-grade myofibroblastic sarcoma of the vulva. Gynecol Oncol. 2004;92:361–4.

    Article  PubMed  Google Scholar 

  54. Miguel San P, Fernández G, Ortiz-Rey JA, Larrauri P. Low-grade myofibroblastic sarcoma of the distal phalanx. J Hand Surg Am. 2004;29:1160–3.

    Article  Google Scholar 

  55. Yamada T, Yoshimura T, Kitamura N, Sasabe E, Ohno S, Yamamoto T. Low-grade myofibroblastic sarcoma of the palate. Int J Oral Sci. 2013;4:170–3.

    Article  Google Scholar 

  56. Demarosi F, Bay A, Moneghini L, Carrassi A. Low-grade myofibroblastic sarcoma of the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:248–54.

    Article  PubMed  Google Scholar 

  57. Mikami Y, Fujii S, Kohashi K, Yamada Y, Moriyama M, Kawano S, Nakamura S, Oda Y, Kiyoshima T. Low-grade myofibroblastic sarcoma arising in the tip of the tongue with intravascular invasion: a case report. Oncol Lett. 2018;16(3):3889–94.

    PubMed  PubMed Central  Google Scholar 

  58. Gabbiani G, Ryan GB, Majne G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia. 1971;27:549–50.

    Article  CAS  PubMed  Google Scholar 

  59. Follonier L, Schaub S, Meister JJ, Hinz B. Myofibroblast communication is controlled by intercellular mechanical coupling. J Cell Sci. 2008;121:3305–16.

    Article  CAS  PubMed  Google Scholar 

  60. Mentzel T. Low-grade myofibroblastic sarcoma. In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, editors. World Health Organization classification of tumours: pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2013. p. 85–6.

    Google Scholar 

  61. Tomasek JJ, Gabbianr G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol. 2002;3:349–63.

    Article  CAS  PubMed  Google Scholar 

  62. Niedzielska I, Janic T, Mrowiec B. Low-grade myofibroblastic sarcoma of the mandible: a case report. J Med Case Rep. 2009;3:8458.

    Article  PubMed  PubMed Central  Google Scholar 

  63. Oda Y, Sakamoto A, Saito T, Kawauchi S, Iwamoto Y, Tstuneyoshi M. Molecular abnormalities of p53, MDM2, and H-ras in synovial sarcoma. Mod Pathol. 2000;13:994–1004.

    Article  CAS  PubMed  Google Scholar 

  64. Erickson-Johnson MR, Chou MM, Evers BR, Roth CW, Seys AR, Jin L, et al. Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion. Lab Investig. 2011;91:1427–33.

    Article  CAS  PubMed  Google Scholar 

  65. Kohashi K, Oda Y, Yamamoto H, Tamiya S, Matono H, Iwamoto Y, et al. Reduced expression of SMARCB1/INI1 protein in synovial sarcoma. Mod Pathol. 2010;23:981–90.

    Article  CAS  PubMed  Google Scholar 

  66. Lee PJ, Yoo NS, Hagemann IS, Pfeifer JD, Cottrell CE, Abel HJ, et al. Spectrum of mutations in leiomyosarcomas identified by clinical targeted next-generation sequencing. ERP Mol Pathol. 2017;102:156–61.

    Article  CAS  Google Scholar 

  67. Overholtzer M, Rao PH, Favis R, Lu XY, Elowitz MB, Barany F, et al. The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability. Proc Natl Acad Sci U S A. 2003;100:11547–52.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  68. Cerio R. Spindle cell neoplasms. J Eur Acad Dermatol Venereol. 1998;11:52.

    Article  Google Scholar 

  69. Jo VY, Fletcher CD. WHO classification of soft tissue tumours: an update based on the 2013. Pathology. 2014;46:95–104.

    Article  CAS  PubMed  Google Scholar 

  70. Teleb M, Olivas CC, Kanu O, Ramos LD, Sumayin N, Albaghdadi A, et al. Spindle-cell sarcoma involving the major pulmonary arteries. PRO. 2017;30:311–3.

    Google Scholar 

  71. Siyad AK, Gopi P, Jayan NP, Augustine J. Spindle cell sarcoma of thyroid: a case report. Indian J Surg Oncol. 2014;5:312–4.

    Article  PubMed  PubMed Central  Google Scholar 

  72. Fletcher CD. The evolving classification of soft tissue tumours–an update based on the new 2013 WHO classification. Histopathology. 2014;64:2–11.

    Article  PubMed  Google Scholar 

  73. Bills V, Iqbal R, Haqqani M, Clague JE. Spindle cell sarcoma: a rare cause of a large abdominal mass. Age Ageing. 2005;34:88–9.

    Article  CAS  PubMed  Google Scholar 

  74. Mehra S, Ibrahim O, Moshiri M, Cahill J, Bhargava P. Spindle-cell sarcoma of the heart: a rare cause for a cardiac mass. Radiol Case Rep. 2012;7:792.

    Article  PubMed  Google Scholar 

  75. Patel KN, Jha RK, Pandya SJ. Surgical management of primary spindle cell sarcoma of prostate. Urology. 2017;105:7–8.

    Article  Google Scholar 

  76. Muturi A, Kotecha V, Ruturi J, Muhinga M, Waweru W. High-grade spindle cell sarcoma of the heart: a case report and review of literature. J Cardiothorac Surg. 2015;10:46.

    Article  PubMed  PubMed Central  Google Scholar 

  77. Lokesh V, Naveen T, Pawar YS. Spindle cell sarcoma of esophagus: a rare case presentation. J Cancer Res Therap. 2010;6:100–1.

    Article  CAS  Google Scholar 

  78. Bhaumik G, Chatterjee K. Spindle cell sarcoma of the maxillary antrum. J Indian Med Assoc. 2012;110:657–8.

    PubMed  Google Scholar 

  79. Borden EC, Baker LH, Bell RS, Bramwell V, Demetri GD, Eisenberg BL, et al. Soft tissue sarcomas of adults: state of the translational science. Clin Cancer Res. 2003;9:1941–56.

    PubMed  Google Scholar 

  80. Feng L, Wang M, Yibulayin F, Zhang H, Yang Y, Ren F, Wushou A. Spindle cell sarcoma: a SEER population-based analysis. Sci Rep. 2018;8:5024.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  81. Wushou A, Jiang YZ, Liu YR, Shao ZM. The demographic features, clinicopathologic characteristics, treatment outcome and disease-specific prognostic factors of solitary fibrous tumor: a population-based analysis. Oncotarget. 2015;6:41875–83.

    Article  PubMed  PubMed Central  Google Scholar 

  82. Feng L, Cai D, Muhetaer A, Yang YL, Ren F, Yishake M, et al. Spindle cell carcinoma: the general demographics, basic clinico-pathologic characteristics, treatment, outcome and prognostic factors. Oncotarget. 2017;8:43228–36.

    Article  PubMed  PubMed Central  Google Scholar 

  83. Collini P, Sorensen PHB, Patel S, Blay JY, Issels RD, Maki RG, et al. Sarcomas with spindle cell morphology. Semin Oncol. 2009;36:324–37.

    Article  PubMed  Google Scholar 

  84. Kaposi sarcoma treatment. National Cancer Institute. 2017.

    Google Scholar 

  85. Schwartz RA, Micali G, Nasca MR, Scuderi L. Kaposi sarcoma: a continuing conundrum. J Am Acad Dermatol. 2008;59(2):179–206.

    Article  PubMed  Google Scholar 

  86. Hoffmann C, Sabranski M, Esser S. HIV-associated Kaposi’s sarcoma. Oncol Res Treat. 2017;40(3):94–8.

    Article  CAS  PubMed  Google Scholar 

  87. Ferri, Fred F. Ferri’s clinical advisor. 2018 E-Book: 5 Books in 1. Elsevier Health Sciences. 2017. p. 735.

    Google Scholar 

  88. Kaposi Sarcoma Treatment. National Cancer Institute. 2015.

    Google Scholar 

  89. Kaposi M. Idiopathisches multiples Pigmentsarkom der Haut. Arch Dermatol Syph. 1872;4(2):265–73.

    Article  Google Scholar 

  90. Ablashi DV, Chatlynne LG, Whitman JE, Cesarman E. Spectrum of Kaposi’s sarcoma-associated herpesvirus, or human herpesvirus 8, diseases. Clin Microbiol Rev. 2002;15(3):439–64.

    Article  PubMed  PubMed Central  Google Scholar 

  91. Pauk J, Huang ML, Brodie SJ, Wald A, Koelle DM, Schacker T, et al. Mucosal shedding of human herpesvirus 8 in men. N Engl J Med. 2000;343(19):1369–77.

    Article  CAS  PubMed  Google Scholar 

  92. Parravicini C, Olsen SJ, Capra M, Poli F, Sirchia G, Gao SJ, et al. Risk of Kaposi’s sarcoma-associated herpes virus transmission from donor allografts among Italian posttransplant Kaposi’s sarcoma patients. Blood. 1997;90(7):2826–9.

    CAS  PubMed  Google Scholar 

  93. Hladik W, Dollard SC, Mermin J, Fowlkes AL, Downing R, Amin MM, et al. Transmission of human herpesvirus 8 by blood transfusion. N Engl J Med. 2006;355(13):1331–8.

    Article  CAS  PubMed  Google Scholar 

  94. Coffin JM, Hughes SH, Varmus HE. Retroviruses. Cold Spring Harbor: Cold Spring Harbor Laboratory Press; 1997.

    Google Scholar 

  95. Ensoli B, Sirianni MC. Kaposi’s sarcoma pathogenesis: a link between immunology and tumor biology. Crit Rev Oncog. 1998;9(2):107–24.

    Article  CAS  PubMed  Google Scholar 

  96. Gurzu S, Ciortea D, Munteanu T, Kezdi-Zaharia I, Jung I. Mesenchymal-to-endothelial transition in Kaposi sarcoma: a histogenetic hypothesis based on a case series and literature review. PLoS One. 2008;8(8):e71530.

    Article  CAS  Google Scholar 

  97. Beckstead JH, Wood GS, Fletcher V. Evidence for the origin of Kaposi’s sarcoma from lymphatic endothelium. Am J Pathol. 1985;119(2):294–300.

    CAS  PubMed  PubMed Central  Google Scholar 

  98. Rosai J. Rosai and Ackerman’s surgical pathology. 10th ed. St. Louis: Mosby; 2011.

    Google Scholar 

  99. Weninger W, et al. Expression of vascular endothelial growth factor receptor-3 and podoplanin suggest a lymphatic endothelial origin of Kaposi’s sarcoma tumor cells. Lab Investig. 1999;79:243–51.

    CAS  PubMed  Google Scholar 

  100. Dezube BJ. Clinical presentation and natural history of AIDS–related Kaposi’s sarcoma. Hematol Oncol Clin North Am. 1996;10(5):1023–9.

    Article  CAS  PubMed  Google Scholar 

  101. Kaposi’s Sarcoma. Taber’s cylcopedic medical dictionary, vol. 21. Philadelphia: FA Davis Company; 2009. p. 1256.

    Google Scholar 

  102. Soyer HP, Jakob L, Metzler G, Chen KM, Garbe C. Non-AIDS associated Kaposi’s sarcoma: clinical features and treatment outcome. PLoS ONE. 2011;6(4):e18397.

    Article  CAS  Google Scholar 

  103. Nichols CM, Flaitz CM, Hicks MJ. Treating Kaposi’s lesions in the HIV-infected patient. JADA. 1993;124(11):78–84.

    CAS  PubMed  Google Scholar 

  104. Danzig JB, Brandt LJ, Reinus JF, Klein RS. Gastrointestinal malignancy in patients with AIDS. Am J Gastroenterol. 1991;86(6):715–8.

    CAS  PubMed  Google Scholar 

  105. Garay SM, Belenko M, Fazzini E, Schinella R. Pulmonary manifestations of Kaposi’s sarcoma. Chest. 1987;91(1):39–43.

    Article  CAS  PubMed  Google Scholar 

  106. Blumenfeld W, et al. Differential diagnosis of Kaposi’s sarcoma. Arch Pathol Lab Med. 1985;109:123–7.

    CAS  PubMed  Google Scholar 

  107. James W, Berger T. Elston D Andrews’ diseases of the skin: clinical dermatology. 10th ed. Philadelphia: WB Saunders; 2005.

    Google Scholar 

  108. Kumar P. Classic Kaposi’s sarcoma in Arabs-widening ethnic involvement. J Cancer Res Therap. 2011;7(1):92–4.

    Article  Google Scholar 

  109. Iscovich J, Boffetta P, Winkelmann R, Brennan P, Azizi E. Classic Kaposi’s sarcoma in Jews living in Israel, 1961-1989: a population-based incidence study. AIDS. 1998;12(15):2067–72.

    Article  CAS  PubMed  Google Scholar 

  110. Fenig E, Brenner B, Rakowsky E, Lapidoth M, Katz A, Sulkes A. Classic Kaposi sarcoma: experience at Rabin Medical Center in Israel. Am J Clin Oncol. 1998;21(5):498–500.

    Article  CAS  PubMed  Google Scholar 

  111. Cook-Mozaffari P, Newton R, Beral V, Burkitt DP. The geographical distribution of Kaposi’s sarcoma and of lymphomas in Africa before the AIDS epidemic. Br J Cancer. 1998;78(11):1521–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  112. Olsen SJ, Chang Y, Moore PS, Biggar RJ, Melbye M. Increasing Kaposi’s sarcoma-associated herpesvirus seroprevalence with age in a highly Kaposi’s sarcoma endemic region, Zambia in 1985. AIDS. 1998;12(14):1921–5.

    Article  CAS  PubMed  Google Scholar 

  113. Qunibi W, Al-Furayh O, Almeshari K, Lin SF, Sun R, Heston L, Ross D, Rigsby M, Miller G. Serologic association of human herpesvirus eight with posttransplant Kaposi’s sarcoma in Saudi Arabia. Transplantation. 1998;65(4):583–5.

    Article  CAS  PubMed  Google Scholar 

  114. Luppi M, Barozzi P, Schulz TF, Setti G, Staskus K, Trovato R, et al. Bone marrow failure associated with human herpesvirus 8 infection after transplantation. N Engl J Med. 2000;43(19):1378–85.

    Article  Google Scholar 

  115. Borkovic SP, Schwartz RA. Kaposi’s sarcoma presenting in the homosexual man - a new and striking phenomenon. Ariz Med. 1981;38(12):902–4.

    CAS  PubMed  Google Scholar 

  116. Hausen HZ. Rhadinoviruses. Infections causing human cancer. Weinheim: Wiley; 2006.

    Book  Google Scholar 

  117. Drabell FG. Kaposi’s sarcoma and renal diseases. New topics in cancer research. New York: Nova Biomedical Books; 2006.

    Google Scholar 

  118. Beral V, Peterman TA, Berkelman RL, Jaffe HW. Kaposi’s sarcoma among persons with AIDS: a sexually transmitted infection? Lancet. 1990;335(8682):123–8.

    Article  CAS  PubMed  Google Scholar 

  119. Tappero JW, Berger TG, Kaplan LD, Volberding PA, Kahn JO. Cryotherapy for cutaneous Kaposi’s sarcoma (KS) associated with acquired immune deficiency syndrome (AIDS): a phase II trial. AIDS. 1991;4(9):839–46.

    CAS  Google Scholar 

  120. Zimmerman EE, Crawford P. Cutaneous cryosurgery. Am Fam Physician. 2012;86(12):1118–24.

    PubMed  Google Scholar 

  121. Anglemyer A, Agrawal AK, Rutherford GW. Treatment of Kaposi sarcoma in children with HIV-1 infection. Cochrane Database Syst Rev. 2014;1(1):CD009826.

    Google Scholar 

  122. McAllister SC, Hanson RS, Manion RD. Propranolol decreases proliferation of endothelial cells transformed by Kaposi’s sarcoma-associated herpesvirus and induces lytic viral gene expression. J Virol. 2015;89(21):11144–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  123. Abdelmaksoud A, Filoni A, Giudice G, Vestita M. Classic and HIV-related Kaposi sarcoma treated with 0.1% topical timolol gel. JADA. 2017;76(1):153–5.

    Google Scholar 

  124. Gill PS, Tulpule A, Espina BM, Cabriales S, Bresnahan J, Ilaw M, et al. Paclitaxel is safe and effective in the treatment of advanced AIDS-related Kaposi’s sarcoma. J Clin Oncol. 1999;17(6):1876–83.

    Article  CAS  PubMed  Google Scholar 

  125. Sgadari C, Toschi E, Palladino C, Barillari G, Carlei D, Cereseto A, et al. Mechanism of paclitaxel activity in Kaposi’s sarcoma. J Immunol. 2000;165(1):509–17.

    Article  CAS  PubMed  Google Scholar 

  126. Summary of product characteristics. EMA.

    Google Scholar 

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  1. Faculty of Medicine, Alexandria University, Alexandria, Egypt

    Mahmoud F. Sakr

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  1. Mahmoud F. Sakr
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Sakr, M.F. (2022). Neoplastic Lesions of the Tongue. In: Tongue Lesions. Springer, Cham. https://doi.org/10.1007/978-3-031-08198-9_10

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  • DOI: https://doi.org/10.1007/978-3-031-08198-9_10

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