Abstract
Clinical practice guidelines (CPGs) are evidence-based recommendations that use Level I therapeutic evidence from randomized controlled trials (RCTs) to guide nonoperative, operative, and post-operative treatments by determining if a procedure should be done based on the best available evidence. Appropriate use criteria (AUC) are derived from CPGs and can inform clinicians which patients should receive certain procedures. These are derived from relevant evidence and clinician experience and can utilize Level II-V evidence. When used in combination, they can provide important guidance for clinicians to make decisions based on evidence available in the literature, with the caveats that CPGs may not be generalizable to all patient subgroups due to inclusion and exclusion criteria, insufficient statistical power of included RCTs to compare rare outcomes, and inadequate statistical power to conduct subgroup analyses.
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Brown, G.A., Chen, A.F. (2022). Clinical Practice Guidelines and Appropriate Use Criteria to Guide Care. In: Samora, J.B., Shea, K.G. (eds) Quality Improvement and Patient Safety in Orthopaedic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-031-07105-8_11
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