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Small Animal Biomagnetism Applications

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Flexible High Performance Magnetic Field Sensors

Abstract

The functioning of the human brain, nervous system, and heart is based on the conduction of electrical signals. These electrical signals also create magnetic fields which extend outside the human body. Highly sensitive magnetometers, such as superconducting quantum interference device magnetometers or optically pumped magnetometers, placed outside the human body can detect these biomagnetic fields and provide non-invasive measurements of, e.g. brain activity, nerve impulses, and cardiac activity. Animal models are used widely in medical research, including for disease diagnostics and for drugs testing. We review the topic of biomagnetic recordings on animal models using optically pumped magnetometers and present our experiments on detecting nerve impulses in the frog sciatic nerve and the heartbeat in an isolated guinea pig heart.

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Acknowledgements

This work was supported by Novo Nordisk Foundation grant NNF20OC0064182, by the ERC Advanced Grant Quantum-N and by the Villum Foundation.

Author information

Authors and Affiliations

  1. School of Physics and Astronomy, University of Nottingham, Nottingham, UK

    Kasper Jensen

  2. Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

    Bo Hjorth Bentzen

  3. Niels Bohr Institute, University of Copenhagen, Copenhagen, Denmark

    Eugene S. Polzik

Authors
  1. Kasper Jensen
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  2. Bo Hjorth Bentzen
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  3. Eugene S. Polzik
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Corresponding author

Correspondence to Kasper Jensen .

Editor information

Editors and Affiliations

  1. Mag4Health, Grenoble, France

    Etienne Labyt

  2. Biosignals (Magnetoencephalography), Physikalisch-Technische Bundesanstalt, Berlin, Germany

    Tilmann Sander

  3. Medical Physics, University of Wisconsin, Madison, WI, USA

    Ronald Wakai

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Jensen, K., Bentzen, B.H., Polzik, E.S. (2022). Small Animal Biomagnetism Applications. In: Labyt, E., Sander, T., Wakai, R. (eds) Flexible High Performance Magnetic Field Sensors. Springer, Cham. https://doi.org/10.1007/978-3-031-05363-4_3

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