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Immune Tolerance at a Glance

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Textbook of Allergen Tolerance

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Abstract

This chapter focuses on immune tolerance, the antipode of the adaptive immune response. The main mechanisms and participants of central and peripheral tolerance are considered at a glance, taking into account the current presentation of allergen tolerance. This topic has always been complex in basic immunology; therefore, we tried to describe tolerance processes in a simple but thorough manner. Commonly, the immune system is tolerant to self-antigens, antigens of its own symbiotic and opportunistic microbes in the steady-state, food proteins, environmental allergens, and male antigens (inside women). In addition, however, there are such events as tolerance maintenance and breakdown, pathologic and artificial tolerance.

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  1. Clinical Immunology and Allergy Department, Siberian State Medical University, Tomsk, Russia

    Vladimir V. Klimov

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Klimov, V.V. (2022). Immune Tolerance at a Glance. In: Textbook of Allergen Tolerance . Springer, Cham. https://doi.org/10.1007/978-3-031-04309-3_2

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