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Ovulation, Pregnancy, and Delivery in the Female Patient with Hypopituitarism

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Pituitary Disorders throughout the Life Cycle

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Abstract

Patients with hypopituitarism often have hypogonadotropic hypogonadism as part of the constellation of their deficiencies. With this condition, they are unable to spontaneously conceive. Conception and pregnancy can be successfully attained with the use of gonadotropin administration for ovulation induction. Once these patients have successfully conceived, medications used to replace hormonal deficiencies require adjustment throughout pregnancy for optimal management of hypopituitarism. Hormonal needs shift during pregnancy and often require adjustment up until the time of delivery. Some replacement medications may need to be discontinued during pregnancy. Interactions between medications need to be carefully monitored. Labor and delivery require special attention to medication management. Finally, pituitary hormone replacement needs to be readjusted after delivery usually to prepregnancy dosages.

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Authors and Affiliations

  1. Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA

    Alyssa Dominguez & John D. Carmichael

  2. Department of Reproductive Endocrinology and Infertility, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA

    Rachel Danis

  3. USC Pituitary Center, Los Angeles, CA, USA

    John D. Carmichael

Authors
  1. Alyssa Dominguez
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  2. Rachel Danis
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  3. John D. Carmichael
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Corresponding author

Correspondence to John D. Carmichael .

Editor information

Editors and Affiliations

  1. Mayo Clinic, Jacksonville, FL, USA

    Susan L. Samson

  2. Emory University School of Medicine, Atlanta, GA, USA

    Adriana G. Ioachimescu

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Dominguez, A., Danis, R., Carmichael, J.D. (2022). Ovulation, Pregnancy, and Delivery in the Female Patient with Hypopituitarism. In: Samson, S.L., Ioachimescu, A.G. (eds) Pituitary Disorders throughout the Life Cycle. Springer, Cham. https://doi.org/10.1007/978-3-030-99918-6_13

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  • DOI: https://doi.org/10.1007/978-3-030-99918-6_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-99917-9

  • Online ISBN: 978-3-030-99918-6

  • eBook Packages: MedicineMedicine (R0)

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