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Therapeutic Potential of Seleno-Compounds in Cancer—An Overview

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Advances in Chemical, Bio and Environmental Engineering (CHEMBIOEN 2021)

Part of the book series: Environmental Science and Engineering ((ESE))

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Abstract

Researchers are looking for natural agents to tackle high-prevalence cancer cases, for this Selenium (Se) becoming a promising contender because it inhibits the growth of the tumor. Selenium (Se) is a well-known necessary trace component that has been propagated (spread and promote) by non-metallic. Selenium (Se) as a cancer therapeutic agent a report was documented 100 years ago after that another research claimed that selenium (Se) is a carcinogen and an early study claiming that selenium (Se) played role in the prevention of cancer. As an outcome, this remarkable oxygen family member has a wide range of health impacts, including acting as a cancer preventive agent, also act as a toxin and a carcinogen. Numerous clinical trials showed no important significant benefit of selenium (Se) in tumor suppression, the scientists have found that only a few species of selenium (Se) have significant anticancer activities. By suppressing metastasis organic selenium (Se) compounds aid in the treatment of cancer but in comparison with inorganic compounds, they have several disadvantages. The scientists are working on the challenge to improve the Selenium efficacy with toxicity effect. For this nanotechnology has become a solution. The nanoparticle of selenium (SeNPs) is used against various malignant diseases as curative agents. In this review paper, selenium species categorize into three types (Se nanoparticles, organic and inorganic) and an outline of their function in the curing of cancer. To give reliable information on selenium capabilities in the treatment of tumors so it is necessary to review the state of selenium and selenium compounds.

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Acknowledgements

Authors are thankful to Chandigarh University for providing support for carrying out this research.

Author Contribution

A.R.P. had the idea for the article, A.R.P had performed the literature search and data analysis, and A.R.P and S.S. had drafted and critically revised the work.

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  1. UIS-Chemistry, Chandigarh University, Gharuan, Punjab, India

    Anu Radha Pathania & Swati Sharma

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  1. Anu Radha Pathania
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  2. Swati Sharma
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Correspondence to Anu Radha Pathania .

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Editors and Affiliations

  1. Department of Chemical Engineering, Dr. B. R. Ambedkar National Institute of Technology Jalandhar, Jalandhar, Punjab, India

    Jatinder Kumar Ratan

  2. Department of Chemical Engineering, Dr. B. R. Ambedkar National Institute of Technology Jalandhar, Jalandhar, Punjab, India

    Deepak Sahu

  3. Department of Chemical Engineering, Dr. B. R. Ambedkar National Institute of Technology Jalandhar, Jalandhar, Punjab, India

    Nitin Naresh Pandhare

  4. Department of Chemical Engineering, Dr. B. R. Ambedkar National Institute of Technology Jalandhar, Jalandhar, Punjab, India

    Anjireddy Bhavanam

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Pathania, A.R., Sharma, S. (2022). Therapeutic Potential of Seleno-Compounds in Cancer—An Overview. In: Ratan, J.K., Sahu, D., Pandhare, N.N., Bhavanam, A. (eds) Advances in Chemical, Bio and Environmental Engineering. CHEMBIOEN 2021. Environmental Science and Engineering. Springer, Cham. https://doi.org/10.1007/978-3-030-96554-9_57

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