Abstract
Underground water contamination is a big challenge of this century. Emerging organic contaminants (EOC), personal care products (PCPs), industrial products, pesticides, pharmaceuticals, engineered nanomaterials, veterinary products, and food additives may pose threat to human health, and ecosystem. The ground water contamination which is the main source of drinking water, is an area of greater concern for the present and future of human civics. This chapter encompasses the possible emission sources in groundwater, contaminated surface water, and the fate of EOC, PCPs, and pharmaceuticals. The advancements in analytical techniques and precise equipment, quantitative detection of these contaminants is now possible and more compounds can be speckled now. Probably it is not possible to remove these pollutants from underground water reservoirs; however; detection of contaminants, their control at source, awareness campaigns and regulatory framework are possible approaches to compete this alarming challenge.
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Abe, A. (1999). Distribution of 1, 4-dioxane in relation to possible sources in the water environment. Science of the total environment, 227(1), 41–47.
Ahrens, L., Felizeter, S., Sturm, R., Xie, Z., & Ebinghaus, R. (2009). Polyfluorinated compounds in waste water treatment plant effluents and surface waters along the River Elbe, Germany. Marine pollution bulletin, 58(9), 1326–1333.
Awad, Y. M., Kim, S. C., Abd El-Azeem, S. A., Kim, K. H., Kim, K. R., Kim, K.,.. & Ok, Y. S. (2014). Veterinary antibiotics contamination in water, sediment, and soil near a swine manure composting facility. Environmental earth sciences, 71(3), 1433–1440.
Barnes, K. K., Christenson, S. C., Kolpin, D. W., Focazio, M. J., Furlong, E. T., Zaugg, S. D.,.. & Barber, L. B. (2004). Pharmaceuticals and other organic waste water contaminants within a leachate plume downgradient of a municipal landfill. Groundwater Monitoring & Remediation, 24(2), 119–126.
Barnes, K. K., Kolpin, D. W., Furlong, E. T., Zaugg, S. D., Meyer, M. T., & Barber, L. B. (2008). A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States—I) Groundwater. Science of the total environment, 402(2–3), 192–200.
Bartelt-Hunt, S., Snow, D. D., Damon-Powell, T., & Miesbach, D. (2011). Occurrence of steroid hormones and antibiotics in shallow groundwater impacted by livestock waste control facilities. Journal of contaminant hydrology, 123(3–4), 94–103.
Bauld, J. (1996, May). Groundwater quality: human impact on a hidden resource. In NATIONAL CONFERENCE PUBLICATION-INSTITUTION OF ENGINEERS AUSTRALIA NCP (Vol. 1, pp. 143–148). Institution of Engineers, Australia.
Behera, S. K., Kim, H. W., Oh, J. E., & Park, H. S. (2011). Occurrence and removal of antibiotics, hormones, and several other pharmaceuticals in wastewater treatment plants of the largest industrial city of Korea. Science of the total environment, 409(20), 4351–4360.
Benotti, M. J., & Brownawell, B. J. (2009). Microbial degradation of pharmaceuticals in estuarine and coastal seawater. Environmental Pollution, 157(3), 994–1002.
Besse, J. P., & Garric, J. (2008). Human pharmaceuticals in surface waters: Implementation of a prioritization methodology and application to the French situation. Toxicology Letters, 176(2), 104–123.
Bexfield, L. M., Toccalino, P. L., Belitz, K., Foreman, W. T., & Furlong, E. T. (2019). Hormones and pharmaceuticals in groundwater are used as a source of drinking water across the United States. Environmental science & technology, 53(6), 2950–2960.
Boorman, G. A. (1999). Drinking water disinfection byproducts: review and approach to toxicity evaluation. Environmental health perspectives, 107(suppl 1), 207–217.
Bradley, P. M., Barber, L. B., Duris, J. W., Foreman, W. T., Furlong, E. T., Hubbard, L. E.,.. & Kolpin, D. W. (2014). Riverbank filtration potential of pharmaceuticals in a wastewater-impacted stream. Environmental pollution, 193, 173–180.
Bradley, P. M., Barber, L. B., Kolpin, D. W., McMahon, P. B., & Chapelle, F. H. (2007). Biotransformation of caffeine, cotinine, and nicotine in stream sediments: Implications for use as wastewater indicators. Environmental Toxicology and Chemistry: An International Journal, 26(6), 1116–1121.
Bruchet, A., Hochereau, C., Picard, C., Decottignies, V., Rodrigues, J. M., & Janex-Habibi, M. L. (2005). Analysis of drugs and personal care products in French source and drinking waters: the analytical challenge and examples of application. Water science and technology, 52(8), 53–61.
Buerge, I. J., Buser, H. R., Kahle, M., Muller, M. D., & Poiger, T. (2009). Ubiquitous occurrence of the artificial sweetener acesulfame in the aquatic environment: an ideal chemical marker of domestic wastewater in groundwater. Environmental science & technology, 43(12), 4381–4385.
Buerge, I. J., Buser, H. R., Müller, M. D., & Poiger, T. (2003a). Behavior of the polycyclic musks HHCB and AHTN in lakes, two potential anthropogenic markers for domestic wastewater in surface waters. Environmental science & technology, 37(24), 5636–5644.
Buerge, I. J., Buser, H. R., Poiger, T., & Müller, M. D. (2006). Occurrence and fate of the cytostatic drugs cyclophosphamide and ifosfamide in wastewater and surface waters. Environmental science & technology, 40(23), 7242–7250.
Buerge, I. J., Keller, M., Buser, H. R., Müller, M. D., & Poiger, T. (2011). Saccharin and other artificial sweeteners in soils: estimated inputs from agriculture and households, degradation, and leaching to groundwater. Environmental science & technology, 45(2), 615–621.
Buerge, I. J., Poiger, T., Müller, M. D., & Buser, H. R. (2003b). Caffeine, an anthropogenic marker for wastewater contamination of surface waters. Environmental science & technology, 37(4), 691–700.
Burke, V., Greskowiak, J., Asmuß, T., Bremermann, R., Taute, T., & Massmann, G. (2014a). Temperature dependent redox zonation and attenuation of wastewater-derived organic micropollutants in the hyporheic zone. Science of the Total Environment, 482, 53–61.
Burke, V., Richter, D., Hass, U., Duennbier, U., Greskowiak, J., & Massmann, G. (2014b). Redox-dependent removal of 27 organic trace pollutants: compilation of results from tank aeration experiments. Environmental earth sciences, 71(8), 3685–3695.
Buszka, P. M., Yeskis, D. J., Kolpin, D. W., Furlong, E. T., Zaugg, S. D., & Meyer, M. T. (2009). Waste-indicator and pharmaceutical compounds in landfill-leachate-affected ground water near Elkhart, Indiana, 2000–2002. Bulletin of Environmental Contamination and Toxicology, 82(6), 653–659.
C.G. Daughton and T.A.Ternes,“Pharmaceuticals and personal care products in the environment: agents of subtle change?” Environmental Health Perspectives, vol 107, pp. 907–38, 1999a.
Cabeza, Y., Candela, L., Ronen, D., & Teijon, G. (2012). Monitoring the occurrence of emerging contaminants in treated wastewater and groundwater between 2008 and 2010. The Baix Llobregat (Barcelona, Spain). Journal of hazardous materials, 239, 32–39.
Celiz, M. D., Tso, J., & Aga, D. S. (2009). Pharmaceutical metabolites in the environment: analytical challenges and ecological risks. Environmental Toxicology and Chemistry, 28(12), 2473–2484.
Chefetz, B., Mualem, T., & Ben-Ari, J. (2008). Sorption and mobility of pharmaceutical compounds in soil irrigated with reclaimed wastewater. Chemosphere, 73(8), 1335–1343.
Chen, H., Gao, B., Li, H., & Ma, L. Q. (2011). Effects of pH and ionic strength on sulfamethoxazole and ciprofloxacin transport in saturated porous media. Journal of contaminant hydrology, 126(1–2), 29–36.
Clara, M., Strenn, B., & Kreuzinger, N. (2004). Carbamazepine as a possible anthropogenic marker in the aquatic environment: investigations on the behaviour of carbamazepine in wastewater treatment and during groundwater infiltration. Water research, 38(4), 947–954.
Close, M. E. (1996). Survey of pesticides in New Zealand groundwaters, 1994.
Corbel, V., Stankiewicz, M., Pennetier, C., Fournier, D., Stojan, J., Girard, E.,.. & Lapied, B. (2009). Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet. BMC biology, 7(1), 1–11.
Crane, M., Watts, C., & Boucard, T. (2006). Chronic aquatic environmental risks from exposure to human pharmaceuticals. Science of the total environment, 367(1), 23–41.
Cronin, A. A., Rueedi, J., & Morris, B. L. (2006). The effectiveness of selected microbial and chemical indicators to detect sewer leakage impacts on urban groundwater quality. Water science and technology, 54(6–7), 145–152.
Daughton, C. G. (2004). Non-regulated water contaminants: emerging research. Environmental impact assessment review, 24(7–8), 711–732.
Daughton, C. G., & Ternes, T. A. (1999). Pharmaceuticals and personal care products in the environment: agents of subtle change?. Environmental health perspectives, 107(suppl 6), 907–938.
Del Rosario, K. L., Mitra, S., Humphrey Jr, C. P., & O’Driscoll, M. A. (2014). Detection of pharmaceuticals and other personal care products in groundwater beneath and adjacent to onsite wastewater treatment systems in a coastal plain shallow aquifer. Science of the total environment, 487, 216–223.
Doretto, K. M., Peruchi, L. M., & Rath, S. (2014). Sorption and desorption of sulfadimethoxine, sulfaquinoxaline and sulfamethazine antimicrobials in Brazilian soils. Science of the Total Environment, 476, 406–414.
Drewes, J. E. (2009). Ground water replenishment with recycled water—water quality improvements during managed aquifer recharge. Groundwater, 47(4), 502–505.
Drewes, J. E., Arnold, R., & Fox, P. (2000). Fate of pharmaceutical chemicals during groundwater recharge using reclaimed water. National Groundwater Association, Westerville, Ohio, USA.
Drewes, J. E., Heberer, T., Rauch, T., & Reddersen, K. (2003). Fate of pharmaceuticals during ground water recharge. Groundwater Monitoring & Remediation, 23(3), 64–72.
EC. Biocidal Products Directive 98/8/EC
EC. Drinking Water Directive 98/83/EC.
EC. Environmental Quality Standards Directive 2008/105/EC (also known as the Priority Substances Directive)
EC. Groundwater Directive 2006/118/EC
EC. Plant Protection Products Directive 91/414/EEC
EC. Review of priority substances under the WFD, COM(2011)876
EC. Water Framework Directive – 2000/60/EC
Eggen, T., Moeder, M., & Arukwe, A. (2010). Municipal landfill leachates: a significant source for new and emerging pollutants. Science of the Total Environment, 408(21), 5147–5157.
Ellis, J. B. (2006). Pharmaceutical and personal care products (PPCPs) in urban receiving waters. Environmental pollution, 144(1), 184–189.
Ellis, J. B., Revitt, D. M., Lister, P., Willgress, C., & Buckley, A. (2003). Experimental studies of sewer exfiltration. Water Science and Technology, 47(4), 61–67.
Ens, W., Senner, F., Gygax, B., & Schlotterbeck, G. (2014). Development, validation, and application of a novel LC-MS/MS trace analysis method for the simultaneous quantification of seven iodinated X-ray contrast media and three artificial sweeteners in surface, ground, and drinking water. Analytical and bioanalytical chemistry, 406(12), 2789–2798.
EPA, U. (2006). Edition of the drinking water standards and health advisories. US Environmental Protection Agency, Washington, DC, epa.
Erses, A. S., Onay, T. T., & Yenigun, O. (2008). Comparison of aerobic and anaerobic degradation of municipal solid waste in bioreactor landfills. Bioresource technology, 99(13), 5418–5426.
EC. Environmental Quality Standards Directive 2008/105/EC
Fent, K., Weston, A. A., & Caminada, D. (2006). Ecotoxicology of human pharmaceuticals. Aquatic toxicology, 76(2), 122–159.
Fick, J., Söderström, H., Lindberg, R. H., Phan, C., Tysklind, M., & Larsson, D. J. (2009). Contamination of surface, ground, and drinking water from pharmaceutical production. Environmental Toxicology and Chemistry, 28(12), 2522–2527.
Focazio, M. J., Kolpin, D. W., Barnes, K. K., Furlong, E. T., Meyer, M. T., Zaugg, S. D.,.. & Thurman, M. E. (2008). A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States—II) Untreated drinking water sources. Science of the total Environment, 402(2–3), 201–216.
Fram, M. S., & Belitz, K. (2011). Occurrence and concentrations of pharmaceutical compounds in groundwater used for public drinking-water supply in California. Science of the Total Environment, 409(18), 3409–3417.
Fromme, H., Otto, T., & Pilz, K. (2001). Polycyclic musk fragrances in different environmental compartments in Berlin (Germany). Water research, 35(1), 121–128.
Galassi, S., Provini, A., & Halfon, E. (1996). Risk assessment for pesticides and their metabolites in water. International journal of environmental analytical chemistry, 65(1–4), 331–344.
Garrett, P., Moreau, M., & Lowry, J. D. (1986, November). MTBE as a ground water contaminant. In Proceedings of the NWWA-API conference on petroleum hydrocarbons and organic chemicals in ground water-prevention, detection and restoration (pp. 227–238).
Gasser, G., Rona, M., Voloshenko, A., Shelkov, R., Tal, N., Pankratov, I.,.. & Lev, O. (2010). Quantitative evaluation of tracers for quantification of wastewater contamination of potable water sources. Environmental science & technology, 44(10), 3919–3925.
Giger, W., Schaffner, C., & Kohler, H. P. E. (2006). Benzotriazole and tolyltriazole as aquatic contaminants. 1. Input and occurrence in rivers and lakes. Environmental science & technology, 40(23), 7186–7192.
Gilbert, R. M., Marshman, J. A., Schwieder, M., & Berg, R. (1976). Caffeine content of beverages as consumed. Canadian Medical Association Journal, 114(3), 205.
Glassmeyer, S. T., Furlong, E. T., Kolpin, D. W., Cahill, J. D., Zaugg, S. D., Werner, S. L.,.. & Kryak, D. D. (2005). Transport of chemical and microbial compounds from known wastewater discharges: potential for use as indicators of human fecal contamination. Environmental science & technology, 39(14), 5157–5169.
Godfrey, E., Woessner, W. W., & Benotti, M. J. (2007). Pharmaceuticals in on-site sewage effluent and ground water, western Montana. Groundwater, 45(3), 263–271.
González, S., Barceló, D., & Petrovic, M. (2007). Advanced liquid chromatography-mass spectrometry (LC-MS) methods applied to wastewater removal and the fate of surfactants in the environment. TrAC Trends in Analytical Chemistry, 26(2), 116–124.
Gottschall, N., Topp, E., Metcalfe, C., Edwards, M., Payne, M., Kleywegt, S.,.. & Lapen, D. R. (2012). Pharmaceutical and personal care products in groundwater, subsurface drainage, soil, and wheat grain, following a high single application of municipal biosolids to a field. Chemosphere, 87(2), 194–203.
Grice, H. C., & Goldsmith, L. A. (2000). Sucralose-an overview of the toxicity data. Food and Chemical Toxicology, 38(suppl 2).
Grossberger, A., Hadar, Y., Borch, T., & Chefetz, B. (2014). Biodegradability of pharmaceutical compounds in agricultural soils irrigated with treated wastewater. Environmental pollution, 185, 168–177.
Gurr, C. J., & Reinhard, M. (2006). Harnessing natural attenuation of pharmaceuticals and hormones in rivers.
Halling-Sørensen, B. N. N. S., Nielsen, S. N., Lanzky, P. F., Ingerslev, F., Lützhøft, H. H., & Jørgensen, S. E. (1998). Occurrence, fate and effects of pharmaceutical substances in the environment-A review. Chemosphere, 36(2), 357–393.
Hamscher, G., & Hartung, J. (2008). Veterinary antibiotics in dust: sources, environmental concentrations, and possible health hazards. In Pharmaceuticals in the Environment (pp. 95–102). Springer, Berlin, Heidelberg.
Harada, K., Saito, N., Sasaki, K., Inoue, K., & Koizumi, A. (2003). Perfluorooctane sulfonate contamination of drinking water in the Tama River, Japan: estimated effects on resident serum levels. Bulletin of environmental contamination and toxicology, 71(1), 0031–0036.
Hass, U., Duennbier, U., & Massmann, G. (2012). Occurrence and distribution of psychoactive compounds and their metabolites in the urban water cycle of Berlin (Germany). Water Research, 46(18), 6013–6022.
Heberer, T. (2002a). Occurrence, fate, and assessment of polycyclic musk residues in the aquatic environment of urban areas—a review. Acta hydrochimica et hydrobiologica, 30(5–6), 227–243.
Heberer, T. (2002b). Tracking persistent pharmaceutical residues from municipal sewage to drinking water. Journal of hydrology, 266(3–4), 175–189.
Heberer, T., Mechlinski, A., Fanck, B., Knappe, A., Massmann, G., Pekdeger, A., & Fritz, B. (2004). Field studies on the fate and transport of pharmaceutical residues in bank filtration. Groundwater Monitoring & Remediation, 24(2), 70–77.
Hilton, M. J., Thomas, K. V., & Ashton, D. (2003). Targeted monitoring programme for pharmaceuticals in the aquatic environment. Bristol: Environment agency.
H-J. Stan et al.,“Occurrence of clofibric acid in the aquatic system - is the use of human medical care the source of the contamination of surface, ground and drinking water?,” Vom Wasser, vol 83, pp.57–68, 1994
Horii, Y., Reiner, J. L., Loganathan, B. G., Kumar, K. S., Sajwan, K., & Kannan, K. (2007). Occurrence and fate of polycyclic musks in wastewater treatment plants in Kentucky and Georgia, USA. Chemosphere, 68(11), 2011–2020.
Houtman, C. J. (2010). Emerging contaminants in surface waters and their relevance for the production of drinking water in Europe. Journal of Integrative Environmental Sciences, 7(4), 271–295.
Hu, X., Zhou, Q., & Luo, Y. (2010). Occurrence and source analysis of typical veterinary antibiotics in manure, soil, vegetables and groundwater from organic vegetable bases, northern China. Environmental Pollution, 158(9), 2992–2998.
Huschek, G., Hansen, P. D., Maurer, H. H., Krengel, D., & Kayser, A. (2004). Environmental risk assessment of medicinal products for human use according to European Commission recommendations. Environmental Toxicology: An International Journal, 19(3), 226–240.
Jeon, H. K., Chung, Y., & Ryu, J. C. (2006). Simultaneous determination of benzophenone-type UV filters in water and soil by gas chromatography–mass spectrometry. Journal of Chromatography A, 1131(1–2), 192–202.
Jim, T. Y., Bouwer, E. J., & Coelhan, M. (2006). Occurrence and biodegradability studies of selected pharmaceuticals and personal care products in sewage effluent. Agricultural water management, 86(1–2), 72–80.
Jobling, S., Reynolds, T., White, R., Parker, M. G., & Sumpter, J. P. (1995). A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Environmental health perspectives, 103(6), 582–587.
Johnson, A. C., Belfroid, A., & Di Corcia, A. (2000). Estimating steroid oestrogen inputs into activated sludge treatment works and observations on their removal from the effluent. Science of the Total Environment, 256(2–3), 163–173.
Johnson, A. C., Hughes, C. D., Williams, R. J., & Chilton, P. J. (1998). Potential for aerobic isoproturon biodegradation and sorption in the unsaturated and saturated zones of a chalk aquifer. Journal of Contaminant Hydrology, 30(3–4), 281–297.
Johnson, A. C., Jürgens, M. D., Williams, R. J., Kümmerer, K., Kortenkamp, A., & Sumpter, J. P. (2008). Do cytotoxic chemotherapy drugs discharged into rivers pose a risk to the environment and human health? An overview and UK case study. Journal of Hydrology, 348(1–2), 167–175.
Jones, O. A. H., Voulvoulis, N., & Lester, J. N. (2002). Aquatic environmental assessment of the top 25 English prescription pharmaceuticals. Water research, 36(20), 5013–5022.
Jurado, A., López-Serna, R., Vázquez-Suné, E., Carrera, J., Pujades, E., Petrovic, M., & Barceló, D. (2014). Occurrence of carbamazepine and five metabolites in an urban aquifer. Chemosphere, 115, 47–53.
Karnjanapiboonwong, A., Morse, A. N., Maul, J. D., & Anderson, T. A. (2010). Sorption of estrogens, triclosan, and caffeine in a sandy loam and a silt loam soil. Journal of Soils and Sediments, 10(7), 1300–1307.
Kasprzyk-Hordern, B., Dinsdale, R. M., & Guwy, A. J. (2008). The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK. Water research, 42(13), 3498–3518.
Katz, B. G., Griffin, D. W., & Davis, J. H. (2009). Groundwater quality impacts from the land application of treated municipal wastewater in a large karstic spring basin: chemical and microbiological indicators. Science of the Total Environment, 407(8), 2872–2886.]
Kavanaugh, M. C. (2003). Unregulated and emerging chemical contaminants: technical and institutional challenges. Proceedings of the water environment federation, 2003(12), 1–19.
Kim, K. R., Owens, G., Kwon, S. I., So, K. H., Lee, D. B., & Ok, Y. S. (2011). Occurrence and environmental fate of veterinary antibiotics in the terrestrial environment. Water, Air, & Soil Pollution, 214(1), 163–174.
Knee, K. L., Gossett, R., Boehm, A. B., & Paytan, A. (2010). Caffeine and agricultural pesticide concentrations in surface water and groundwater on the north shore of Kauai (Hawaii, USA). Marine Pollution Bulletin, 60(8), 1376–1382.
Kolpin, D. W., Barbash, J. E., & Gilliom, R. J. (1998). Occurrence of pesticides in shallow groundwater of the United States: Initial results from the National Water-Quality Assessment Program. Environmental Science & Technology, 32(5), 558–566.
Kolpin, D. W., Schnoebelen, D. J., & Thurman, E. M. (2004). Degradates provide insight to spatial and temporal trends of herbicides in ground water. Groundwater, 42(4), 601–608.
Kolpin, D. W., Thurman, E. M., & Linhart, S. M. (2000). Finding minimal herbicide concentrations in ground water? Try looking for their degradates. Science of the Total Environment, 248(2–3), 115–122.
Kosjek, T., Andersen, H. R., Kompare, B., Ledin, A., & Heath, E. (2009). Fate of carbamazepine during water treatment. Environmental science & technology, 43(16), 6256–6261.
Kümmerer, K. (2009). The presence of pharmaceuticals in the environment due to human use–present knowledge and future challenges. Journal of environmental management, 90(8), 2354–2366.
Kuroda, K., Murakami, M., Oguma, K., Muramatsu, Y., Takada, H., & Takizawa, S. (2012). Assessment of groundwater pollution in Tokyo using PPCPs as sewage markers. Environmental science & technology, 46(3), 1455–1464.
Lapworth, D. J., & Gooddy, D. C. (2006). Source and persistence of pesticides in a semi-confined chalk aquifer of southeast England. Environmental Pollution, 144(3), 1031–1044.
Lapworth, D. J., Baran, N., Stuart, M. E., & Ward, R. S. (2012). Emerging organic contaminants in groundwater: a review of sources, fate and occurrence. Environmental pollution, 163, 287–303.
Lapworth, D. J., Gooddy, D. C., Allen, D., & Old, G. H. (2009). Understanding groundwater, surface water, and hyporheic zone biogeochemical processes in a Chalk catchment using fluorescence properties of dissolved and colloidal organic matter. Journal of Geophysical Research: Biogeosciences, 114(G3).
Lara-Martín, P. A., Li, X., Bopp, R. F., & Brownawell, B. J. (2010). Occurrence of alkyltrimethylammonium compounds in urban estuarine sediments: behentrimonium as a new emerging contaminant. Environmental science & technology, 44(19), 7569–7575.
Laws, B. V., Dickenson, E. R., Johnson, T. A., Snyder, S. A., & Drewes, J. E. (2011). Attenuation of contaminants of emerging concern during surface-spreading aquifer recharge. Science of the Total Environment, 409(6), 1087–1094.
Lewandowski, J., Putschew, A., Schwesig, D., Neumann, C., & Radke, M. (2011). Fate of organic micropollutants in the hyporheic zone of a eutrophic lowland stream: Results of a preliminary field study. Science of the Total Environment, 409(10), 1824–1835.
Lin, K., & Gan, J. (2011). Sorption and degradation of wastewater-associated non-steroidal anti-inflammatory drugs and antibiotics in soils. Chemosphere, 83(3), 240–246.
Lindsey, M. E., Meyer, M., & Thurman, E. M. (2001). Analysis of trace levels of sulfonamide and tetracycline antimicrobials in groundwater and surface water using solid-phase extraction and liquid chromatography/mass spectrometry. Analytical chemistry, 73(19), 4640–4646.
Lindström, A., Buerge, I. J., Poiger, T., Bergqvist, P. A., Müller, M. D., & Buser, H. R. (2002). Occurrence and environmental behavior of the bactericide triclosan and its methyl derivative in surface waters and in wastewater. Environmental science & technology, 36(11), 2322–2329.
Liu, Z. H., Kanjo, Y., & Mizutani, S. (2010). A review of phytoestrogens: their occurrence and fate in the environment. Water research, 44(2), 567–577.
Loftin, K. A., Adams, C. D., Meyer, M. T., & Surampalli, R. (2008). Effects of ionic strength, temperature, and pH on degradation of selected antibiotics. Journal of environmental quality, 37(2), 378–386.
Loos, R., Locoro, G., Comero, S., Contini, S., Schwesig, D., Werres, F.,.. & Gawlik, B. M. (2010). Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water. Water research, 44(14), 4115–4126.
López-Serna, R., Jurado, A., Vázquez-Suñé, E., Carrera, J., Petrović, M., & Barceló, D. (2013). Occurrence of 95 pharmaceuticals and transformation products in urban groundwaters underlying the metropolis of Barcelona, Spain. Environmental Pollution, 174, 305–315.
Martínez, J. L. (2008). Antibiotics and antibiotic resistance genes in natural environments. Science, 321(5887), 365–367.
McArthur, J. V., & Tuckfield, R. C. (2000). Spatial patterns in antibiotic resistance among stream bacteria: effects of industrial pollution. Applied and Environmental Microbiology, 66(9), 3722–3726.
Mezcua, M., Gómez, M. J., Ferrer, I., Aguera, A., Hernando, M. D., & Fernández-Alba, A. R. (2004). Evidence of 2, 7/2, 8-dibenzodichloro-p-dioxin as a photodegradation product of triclosan in water and wastewater samples. Analytica Chimica Acta, 524(1–2), 241–247.
Miller, K. J., & Meek, J. (2006). Helena Valley ground water: pharmaceuticals, personal care products, endocrine disruptors (PPCPs), and microbial indicators of fecal contamination. Helena, MT: Montana Department of Environmental Quality.
Missimer, T. M., Drewes, J. E., Maliva, R. G., & Amy, G. (2011). Aquifer recharge and recovery: groundwater recharge systems for treatment, storage, and water reclamation. Groundwater, 49(6), 771–771.
Mitch, W. A., Sharp, J. O., Trussell, R. R., Valentine, R. L., Alvarez-Cohen, L., & Sedlak, D. L. (2003). N-nitrosodimethylamine (NDMA) as a drinking water contaminant: a review. Environmental engineering science, 20(5), 389–404.
Moldovan, Z. (2006). Occurrences of pharmaceutical and personal care products as micropollutants in rivers from Romania. Chemosphere, 64(11), 1808–1817.
Montgomery-Brown, J., & Reinhard, M. (2003). Occurrence and behavior of alkylphenol polyethoxylates in the environment. Environmental engineering science, 20(5), 471–486.
Moran, M. J., Zogorski, J. S., & Squillace, P. J. (2005). MTBE and gasoline hydrocarbons in ground water of the United States. Groundwater, 43(4), 615–627.
Moran, M. J., Zogorski, J. S., & Squillace, P. J. (2007). Chlorinated solvents in groundwater of the United States. Environmental science & technology, 41(1), 74–81.
Morasch, B. (2013). Occurrence and dynamics of micropollutants in a karst aquifer. Environmental pollution, 173, 133–137.
Mueller, B., Scheytt, T., & Asbrand, M. (2011). Quantification of exchange rates between groundwater and surface water applying pharmaceutical compounds–the Nuthegraban case. In Geophysical Research Abstracts (Vol. 13, pp. EGU2011-2257).
Murray, K. E., Thomas, S. M., & Bodour, A. A. (2010). Prioritizing research for trace pollutants and emerging contaminants in the freshwater environment. Environmental pollution, 158(12), 3462–3471.
Musolff, A., Leschik, S., Möder, M., Strauch, G., Reinstorf, F., & Schirmer, M. (2009). Temporal and spatial patterns of micropollutants in urban receiving waters. Environmental pollution, 157(11), 3069–3077.
Musson, S. E., & Townsend, T. G. (2009). Pharmaceutical compound content of municipal solid waste. Journal of Hazardous Materials, 162(2–3), 730–735.
Nikolaou, A., Meric, S., & Fatta, D. (2007). Occurrence patterns of pharmaceuticals in water and wastewater environments. Analytical and bioanalytical chemistry, 387(4), 1225–1234.
Osenbrück, K., Gläser, H. R., Knöller, K., Weise, S. M., Möder, M., Wennrich, R.,.. & Strauch, G. (2007). Sources and transport of selected organic micropollutants in urban groundwater underlying the city of Halle (Saale), Germany. Water research, 41(15), 3259–3270.
Pal, A., Gin, K. Y. H., Lin, A. Y. C., & Reinhard, M. (2010). Impacts of emerging organic contaminants on freshwater resources: review of recent occurrences, sources, fate and effects. Science of the total environment, 408(24), 6062–6069.
Peng, X., Ou, W., Wang, C., Wang, Z., Huang, Q., Jin, J., & Tan, J. (2014). Occurrence and ecological potential of pharmaceuticals and personal care products in groundwater and reservoirs in the vicinity of municipal landfills in China. Science of the Total Environment, 490, 889–898.
Pérez, S., & Barceló, D. (2007). Fate and occurrence of X-ray contrast media in the environment. Analytical and bioanalytical chemistry, 387(4), 1235–1246.
Petrovic, M., & Barceló, D. (2006). Application of liquid chromatography/quadrupole time-of-flight mass spectrometry (LC-QqTOF-MS) in the environmental analysis. Journal of mass spectrometry, 41(10), 1259–1267.
Petrović, M., Škrbić, B., Živančev, J., Ferrando-Climent, L., & Barcelo, D. (2014). Determination of 81 pharmaceutical drugs by high-performance liquid chromatography coupled to mass spectrometry with hybrid triple quadrupole–linear ion trap in different types of water in Serbia. Science of the total environment, 468, 415–428.
Pham, T. P. T., Cho, C. W., & Yun, Y. S. (2010). Environmental fate and toxicity of ionic liquids: a review. Water research, 44(2), 352–372.
Phillips, P. J., Schubert, C., Argue, D., Fisher, I., Furlong, E. T., Foreman, W.,.. & Chalmers, A. (2015). Concentrations of hormones, pharmaceuticals and other micropollutants in groundwater affected by septic systems in New England and New York. Science of the Total Environment, 512, 43–54.
Poynton, H. C., & Vulpe, C. D. (2009). Ecotoxicogenomics: emerging technologies for emerging contaminants 1. JAWRA Journal of the American Water Resources Association, 45(1), 83–96.
Rabiet, M., Togola, A., Brissaud, F., Seidel, J. L., Budzinski, H., & Elbaz-Poulichet, F. (2006). Consequences of treated water recycling as regards pharmaceuticals and drugs in surface and ground waters of a medium-sized Mediterranean catchment. Environmental science & technology, 40(17), 5282–5288.
Radović, T., Grujić, S., Petković, A., Dimkić, M., & Laušević, M. (2014). Determination of pharmaceuticals and pesticides in river sediments and corresponding surface and groundwater in the Danube River and tributaries in Serbia. Environmental Monitoring and Assessment, 187(1), 1–17.
Rahman, F., Langford, K. H., Scrimshaw, M. D., & Lester, J. N. (2001). Polybrominated diphenyl ether (PBDE) flame retardants. Science of the Total Environment, 275(1–3), 1–17.
Ricart, M., Guasch, H., Alberch, M., Barceló, D., Bonnineau, C., Geiszinger, A.,.. & Sabater, S. (2010). Triclosan persistence through wastewater treatment plants and its potential toxic effects on river biofilms. Aquatic Toxicology, 100(4), 346–353.
Richardson, M. L., & Bowron, J. M. (1985). The fate of pharmaceutical chemicals in the aquatic environment. Journal of Pharmacy and Pharmacology, 37(1), 1–12.
Richardson, S. D., & Ternes, T. A. (2011). Water analysis: emerging contaminants and current issues. Analytical chemistry, 83(12), 4614–4648.
S.D. Richardson, “Water analysis: emerging contaminants and current issues,” Analytical Chemistry, vol. 79, pp. 4295–324, 2007.
Saito, N., Sasaki, K., Nakatome, K., Harada, K., Yoshinaga, T., & Koizumi, A. (2003). Perfluorooctane sulfonate concentrations in surface water in Japan. Archives of Environmental Contamination and Toxicology, 45(2), 149–158.
Salgado, R., Marques, R., Noronha, J. P., Carvalho, G., Oehmen, A., & Reis, M. A. M. (2012). Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant. Environmental Science and Pollution Research, 19(5), 1818–1827.
Sarmah, A. K., Meyer, M. T., & Boxall, A. B. (2006). A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere, 65(5), 725–759.
Schaider, L. A., Rudel, R. A., Ackerman, J. M., Dunagan, S. C., & Brody, J. G. (2014). Pharmaceuticals, perfluorosurfactants, and other organic wastewater compounds in public drinking water wells in a shallow sand and gravel aquifer. Science of the Total Environment, 468, 384–393.
Schwarzenbach, R. P., Escher, B. I., Fenner, K., Hofstetter, T. B., Johnson, C. A., Von Gunten, U., & Wehrli, B. (2006). The challenge of micropollutants in aquatic systems. Science, 313(5790), 1072–1077.
Seiler, R. L., Zaugg, S. D., Thomas, J. M., & Howcroft, D. L. (1999). Caffeine and pharmaceuticals as indicators of waste water contamination in wells. Groundwater, 37(3), 405–410.
Singer, A. C., Nunn, M. A., Gould, E. A., & Johnson, A. C. (2007). Potential risks associated with the proposed widespread use of Tamiflu. Environmental Health Perspectives, 115(1), 102–106.
Slack, R. J., Gronow, J. R., & Voulvoulis, N. (2005). Household hazardous waste in municipal landfills: contaminants in leachate. Science of the total environment, 337(1–3), 119–137.
Soares, A., Guieysse, B., Jefferson, B., Cartmell, E., & Lester, J. N. (2008). Nonylphenol in the environment: a critical review on occurrence, fate, toxicity and treatment in wastewaters. Environment international, 34(7), 1033–1049.
Spliid, N. H., & Køppen, B. (1998). Occurrence of pesticides in Danish shallow ground water. Chemosphere, 37(7), 1307–1316.
Stan, H. J., & Linkerhägner, M. (1992). Identizierung von 2-(4-Chlorphenoxy)-2-methyl-propionsäure in Grundwasser mittels Kapillar-Gaschromatographie mit Atomemessionsdetektion und Massenspektrometrie. Vom Wasser, 79, 75–88.
Standley, L. J., Rudel, R. A., Swartz, C. H., Attfield, K. R., Christian, J., Erickson, M., & Brody, J. G. (2008). Wastewater-contaminated groundwater as a source of endogenous hormones and pharmaceuticals to surface water ecosystems. Environmental Toxicology and Chemistry: An International Journal, 27(12), 2457–2468.
Stuart, M., & Lapworth, D. (2013). Emerging organic contaminants in groundwater. In Smart Sensors for Real-Time Water Quality Monitoring (pp. 259–284). Springer, Berlin, Heidelberg.
Stuart, M., Lapworth, D., Crane, E., & Hart, A. (2012). Review of risk from potential emerging contaminants in UK groundwater. Science of the Total Environment, 416, 1–21.
Swartz, C. H., Reddy, S., Benotti, M. J., Yin, H., Barber, L. B., Brownawell, B. J., & Rudel, R. A. (2006). Steroid estrogens, nonylphenol ethoxylate metabolites, and other wastewater contaminants in groundwater affected by a residential septic system on Cape Cod, MA. Environmental science & technology, 40(16), 4894–4902.
Tappe, W., Groeneweg, J., & Jantsch, B. (2002). Diffuse atrazine pollution in German aquifers. Biodegradation, 13(1), 3–10.
Teijón, G., Candela, L., Sagristá, E., & Hidalgo, M. (2013). Naproxen adsorption-desorption in a sandy aquifer matrix: characterisation of hysteretic behavior at two different temperature values. Soil and Sediment Contamination: An International Journal, 22(6), 641–653.
Teijon, G., Candela, L., Tamoh, K., Molina-Díaz, A., & Fernández-Alba, A. R. (2010). Occurrence of emerging contaminants, priority substances (2008/105/CE) and heavy metals in treated wastewater and groundwater at Depurbaix facility (Barcelona, Spain). Science of the Total Environment, 408(17), 3584–3595.
Tong, L., Huang, S., Wang, Y., Liu, H., & Li, M. (2014). Occurrence of antibiotics in the aquatic environment of Jianghan Plain, central China. Science of the Total Environment, 497, 180–187.
Tran, N. H., Li, J., Hu, J., & Ong, S. L. (2014). Occurrence and suitability of pharmaceuticals and personal care products as molecular markers for raw wastewater contamination in surface water and groundwater. Environmental Science and Pollution Research, 21(6), 4727–4740.
USEPA, C. (2009). Water: Contaminant Candidate List 3.
Van Stempvoort, D. R., Roy, J. W., Brown, S. J., & Bickerton, G. (2011). Artificial sweeteners as potential tracers in groundwater in urban environments. Journal of Hydrology, 401(1–2), 126–133.
Verliefde, A., Cornelissen, E., Amy, G., Van der Bruggen, B., & Van Dijk, H. (2007). Priority organic micropollutants in water sources in Flanders and the Netherlands and assessment of removal possibilities with nanofiltration. Environmental pollution, 146(1), 281–289.
Voutsa, D., Hartmann, P., Schaffner, C., & Giger, W. (2006). Benzotriazoles, alkylphenols and bisphenol A in municipal wastewaters and in the Glatt River, Switzerland. Environmental Science and Pollution Research, 13(5), 333–341.
Vulliet, E., & Cren-Olivé, C. (2011). Screening of pharmaceuticals and hormones at the regional scale, in surface and groundwaters intended to human consumption. Environmental pollution, 159(10), 2929–2934.
Water UK (2011). “Metaldehyde briefing” 2011. Available: http://www.water.org.uk/home/policy/positions/metaldehyde-briefing
Watkinson, A. J., Murby, E. J., Kolpin, D. W., & Costanzo, S. D. (2009). The occurrence of antibiotics in an urban watershed: from wastewater to drinking water. Science of the total environment, 407(8), 2711–2723.
Weil, E. D., Zhu, W., Patel, N., & Mukhopadhyay, S. M. (1996). A systems approach to flame retardancy and comments on modes of action. Polymer Degradation and Stability, 54(2–3), 125–136.
Wolf, L., Zwiener, C., & Zemann, M. (2012). Tracking artificial sweeteners and pharmaceuticals introduced into urban groundwater by leaking sewer networks. Science of the Total Environment, 430, 8–19.
Yu, Y., Liu, Y., & Wu, L. (2013). Sorption and degradation of pharmaceuticals and personal care products (PPCPs) in soils. Environmental Science and Pollution Research, 20(6), 4261–4267.
Yuan, Q., Snow, D. D., & Bartelt-Hunt, S. L. (2013). Potential water quality impacts originating from land burial of cattle carcasses. Science of the Total Environment, 456, 246–253.
Zanella, R., Adaime, M. B., Peixoto, S. C., Friggi, C. D. A., Prestes, O. D., Machado, S. L.,.. & Primel, E. G. (2011). Herbicides persistence in rice paddy water in southern Brazil. Herbicides-mechanisms and mode of action, 369–382.
Zemann, M., Wolf, L., Grimmeisen, F., Tiehm, A., Klinger, J., Hötzl, H., & Goldscheider, N. (2015). Tracking changing X-ray contrast media application to an urban-influenced karst aquifer in the Wadi Shueib, Jordan. Environmental Pollution, 198, 133–143.
Zhang, C. L. Wang, Y., & Wang, F. A. (2007). Microbial Degradation of Sulfonamides in Soils [J]. Journal of Agro-Environment Science, 5.
Zhang, Y. L., Lin, S. S., Dai, C. M., Shi, L., & Zhou, X. F. (2014). Sorption–desorption and transport of trimethoprim and sulfonamide antibiotics in agricultural soil: effect of soil type, dissolved organic matter, and pH. Environmental Science and Pollution Research, 21(9), 5827–5835.
Zhou, L. J., Ying, G. G., Liu, S., Zhao, J. L., Chen, F., Zhang, R. Q.,.. & Zhang, Q. Q. (2012). Simultaneous determination of human and veterinary antibiotics in various environmental matrices by rapid resolution liquid chromatography–electrospray ionization tandem mass spectrometry. Journal of Chromatography A, 1244, 123–138.
Zuccato, E., Calamari, D., Natangelo, M., & Fanelli, R. (2000). Presence of therapeutic drugs in the environment. The lancet, 355(9217), 1789–1790.
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Ahmad, B., Imran, M. (2022). Emerging Organic Contaminants, Pharmaceuticals and Personal Care Products (PPCPs): A Threat to Water Quality. In: Ahmed, T., Hashmi, M.Z. (eds) Hazardous Environmental Micro-pollutants, Health Impacts and Allied Treatment Technologies. Emerging Contaminants and Associated Treatment Technologies. Springer, Cham. https://doi.org/10.1007/978-3-030-96523-5_6
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