Abstract
Regenerative rehabilitation is an emerging field combining regenerative medicine strategies with evidence-based rehabilitation practices. The overall aim of regenerative rehabilitation is to repair and regenerate organ systems and recover function following injury or illness. This review presents recent advances in regenerative rehabilitation with attention to historical context. The state of the field of development and implementation of therapeutic strategies across anatomic and physiologic systems is discussed. Providing an overview of relevant strategies and examples of early successes, the importance of physiologic functional outcomes is emphasized.
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Acknowledgments
The authors gratefully acknowledge helpful comments and review from Dr. Jarrod Call. Additionally, we acknowledge the work of many colleagues who contributed to the improvement of the understanding of the current state of the field for regenerative rehabilitation, across our collective goals for the advancement of new solutions.
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This work was supported by funding from the Department of Defense, Clinical & Rehabilitative Medicine Research Program: W81XWH-18-1-0710 and W81XWH-20-1-0885 (SMG) and National Institutes of Health T32-AR050938 (CJRP). Opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily endorsed by the Department of Defense or National Institutes of Health.
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Raymond-Pope, C.J., Hoffman, D.B., Saunders, D.L., Greising, S.M. (2022). Historical Perspectives of Regenerative Rehabilitation: Recovering and Restoring Functional Capacity. In: Greising, S.M., Call, J.A. (eds) Regenerative Rehabilitation. Physiology in Health and Disease. Springer, Cham. https://doi.org/10.1007/978-3-030-95884-8_1
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