Abstract
Hypertension in pregnancy is empirically diagnosed when there is sustained systolic (SBP) of ≥140 mmHg, or a sustained diastolic blood pressure (DBP) ≥ 90 mmHg obtained through a standardized technique of measurement using auscultatory (mercury or aneroid devices) or automated methods. An elevated measurement whether systolic or diastolic must be confirmed on repeat measurement before the woman can be considered hypertensive to reduce the potential for misdiagnosis based on spurious reading or the patient’s anxiousness during the measurement.
It has been observed that low to middle income countries (LMICs) bear a disproportionate burden of maternal morbidity and mortality from the various hypertensive disorders of pregnancy. The provision of good quality antenatal care during the first 4 months of pregnancy based on WHO recommendations is an effective intervention that can reduce maternal and neonatal mortality and morbidity from hypertensive disorders of pregnancy.
Keywords
- Hypertension in pregnancy
- Preeclampsia
- Eclampsia
- Gestational hypertension
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Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R. Pre-eclampsia. Lancet. 2010;376:631–44.
National Epidemiology Center, Department of Health. The 2013 Philippine health statistics. 2013. http://www.dohgovph/sites/default/files/publications.
Khan KS, Wojdyla D, Say L, Gulmezoglu AM, Van Look PF. WHO analysis of causes of maternal death: a systematic review. Lancet. 2006;367:1066–74.
American College of Obstetricians and Gynecologists. Executive summary: hypertension in pregnancy. Obstet Gynecol. 2013;122:1122–31.
Brown MA, Magee LA, Kenny LC, et al. The hypertensive disorders of pregnancy: ISSHP classification, diagnosis and management recommendations for international practice. Pregnancy Hypertens. 2018;13:291–310.
Bramham K, Parnell B, Nelson-Piercy C, Seed PT, Postol L, Chappell LC. Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis. BMJ. 2014;348:g2301.
Chappell LC, Enye S, Seed P, Briley AL, Poston L, Shennan AH. Adverse perinatal outcomes and risk factors for preeclampsia in women with chronic hypertension: a prospective study. Hypertension. 2008;51:1002–9.
Lee ES, Oh MJ, Jung JW, et al. The levels of circulating vascular endothelial growth factor and soluble FLT-1 in pregnancies complicated by preeclampsia. J Korean Med Sci. 2007;22:94–8. PubMed: 17297258.
Immunology of preeclampsia; current views and hypothesis. In: Kurpisz M.; Fernandez, N., editors Immunology of human reproduction. Sargent, I.L and Smarason, A.K. BIOS Scientific Publishers; Oxford:, 1995, pp. 355–370.
Clinical practice guidelines on hypertension in pregnancy. Philippine Obstetrical, and Gynecological Society; 2015.
Alexander JM, McIntire DD, Leveno KJ, et al. Magnesium sulfate for the prevention of preeclampsia in women with mild hypertension. Am J Obstet Gynecol. 2006;108:826.
Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol. 2000;183:S1–22.
Kuo VS, Koumantakis G, Gallery ED. Proteinuria and its assessment in normal and hypertensive pregnancy. Am J Obstet Gynecol. 1992;167:723–8.
Morris RK, Riley RD, Doug M, Deeks JJ, Kilby MD. Diagnostic accuracy of spot urinary protein and albumin to creatinine ratios for detection of significant proteinuria or adverse pregnancy outcome in patients with suspected pre-eclampsia: systematic review and meta-analysis. BMJ. 2012;345:e4342.
Phelan LK, Brown MA, Davis GK, Mangos G. A prospective study of the impact of automated dipstick urinalysis on the diagnosis of preeclampsia. Hypertens Pregnancy. 2004;23:135–42.
North RA, Taylor RS, Schellenberg JC. Evaluation of a definition of preeclampsia. Br J Obstet Gynaecol. 1999;106:767–73.
Meher S, Duley L, Hunter K, Askie L. Antiplatelet therapy before or after 16 weeks’ gestation for preventing preeclampsia: an individual participant data meta-analysis. Am J Obstet Gynecol. 2017;216:121.
LeFevre ML, U.S. Preventive Services Task. Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: U.S. Preventive Services Task Force Recommendation Statement. Ann Intern Med. 2014;161:819–26.
Hofmeyr GJ, Lawrie TA, Atallah AN, Duley L, Torloni MR. Calcium supplementation during pregnancy for preventing hypertensive disorders and other related problems. Cochrane Database Syst Rev. 2014;(6):CD001059. https://doi.org/10.1002/14651858.CD001059.pub4.
American College of Obstetricians and Gynecologists. Committee Opinion No. 692: emergent therapy for acute-onset, severe hypertension during pregnancy and the postpartum period. Obstet Gynecol. 2017;129:e90–5.
American College of Obstetricians and Gynecologists. ACOG Practice Bulletin No. 202: gestational hypertension and preeclampsia. Obstet Gynecol. 2019;133:e1–25.
Nij Bivank SW, Duvekot JJ. Nicardipine for the treatment of severe hypertension in pregnancy; a review of the literature. Obstet Gynecol Surv. 2010;65:341.
Brown MA, et al. The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice. Pregnancy Hypertens. 2018;13:291–310.
SOGC Clinical Practice Guideline. Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy: executive summary. J Obstet Gynaecol Can. 2014;36(5):416–38.
Behrens I, Basit S, Melbye M, Lykke JA, Wolfhart J, Bundgaard H, et al. Risk of post-pregnancy hypertension in women with a history of hypertensive disorders of pregnancy: nationwide cohort study. BMJ. 2017;358:3078.
Brown MC, Best KE, Pearce MS, Waugh J, Robson SC, Bell R. Cardiovascular disease risk in women with preeclampsia: systematic review and meta-analysis. Eur J Epidemiol. 2013;281:1–19.
Powe CE, Levine RJ, Karumachi SA. Preeclampsia, a disease of maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease. Circulation. 2011;123:2856–69.
Magee L, von Dadelszen P, Stones W, Mathai M. Diet, lifestyle and place of care. In:The FIGO Textbook of Pregnancy Hypertension: an evidence-based guide to monitoring, prevention and management. London, 2016. 456 p.
Thangaratinam S, Rogozinska E, Jolly K, Glinkowski S, Roseboom T, Tomlinson JW, et al. Effects of interventions in pregnancy on maternal weight and obstetric outcomes: meta-analysis of randomised evidence. BMJ. 2012;344:e2088.
Muktabhant B, Lawrie TA, Lumbiganon P, Laopaiboon M. Diet or exercise, or both, for preventing excessive weight gain in pregnancy. Cochrane Database Syst Rev. 2015;6:CD007145.
Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) Diet. N Engl J Med. 2001;344(1):3–10.
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Santos, M.I., Madrigal-Dy, C., Ona, D.I.D. (2022). Hypertensive Disorders in Pregnancy. In: Ram, C.V.S., Teo, B.W.J., Wander, G.S. (eds) Hypertension and Cardiovascular Disease in Asia. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-030-95734-6_18
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