Skip to main content

Long-Term Sequalae of COVID-19 Infection

  • Chapter
  • First Online:
Principles in Nursing Practice in the Era of COVID-19
  • 412 Accesses

Abstract

Since COVID-19, or SARS-CoV-2, infection was initially identified in late 2019, healthcare professionals have researched and studied the disease process. The focus of medical care and treatment of COVID-19 has been on the acute phase of the illness, although we have learned that symptoms can persist for four or more weeks after being infected with the virus. Several terms have been coined to describe this syndrome, such as “Long-COVID”, “Chronic COVID Syndrome”, “Post-acute COVID-19 syndrome,” or “Persistent Post-COVID Syndrome (PPCS)”. Patients experiencing the symptoms that persist may be called “Long-Haulers.” In this patient population, symptoms persist which inhibit their normal activities of daily living and greatly affect their quality of life. Also, we must consider those patients who have recovered from severe COVID, and who deal with the long-term effects of hospitalization as well as effects on all organ systems. As we strive to gain a better understanding of these symptoms, we as nurses must be able to recognize these long-term sequalae and be aware of the impacts on quality of life and mortality. Specialized aftercare and rehabilitation are needed to assist patients who have “recovered” from the illness.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Chopra V, Flanders SA, O'Malley M, Malani AN, Prescott HC (2021) Sixty-day outcomes among patients hospitalized with COVID-19. Ann Intern Med 174(4):576–578

    Article  Google Scholar 

  2. Carfì A, Bernabei R, Landi F (2020) Persistent symptoms in patients after acute COVID-19. JAMA 324(6):603–605

    Article  Google Scholar 

  3. Huang C, Huang L, Wang Y, Li X, Ren L, Gu X et al (2021) 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet 397(10270):220–232

    Article  CAS  Google Scholar 

  4. Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS et al (2021) Post-acute COVID-19 syndrome. Nat Med 27(4):601–615

    Article  CAS  Google Scholar 

  5. World Health Organization. https://www.who.int/docs/default-source/coronaviruse/risk-comms-updates/update54_clinical_long_term_effects.pdf?sfvrsn=3e63eee5_8

  6. Wang F, Kream RM, Stefano GB (2020) Long-term respiratory and neurological sequelae of COVID-19. Med Sci Monitor 26:e928996

    CAS  Google Scholar 

  7. Oronsky B, Larson C, Hammond TC, Oronsky A, Kesari S, Lybeck M et al (2021) A review of persistent post-COVID syndrome (PPCS). Clin Rev Allergy Immunol:1–9. https://doi.org/10.1007/s12016-021-08848-3

  8. Rai DK, Sharma P, Kumar R (2021) Post covid 19 pulmonary fibrosis. Is it real threat? Indian J Tuberc 68(3):330–333

    Article  Google Scholar 

  9. Siripanthong B, Nazarian S, Muser D, Deo R, Santangeli P, Khanji MY et al (2020) Recognizing COVID-19–related myocarditis: the possible pathophysiology and proposed guideline for diagnosis and management. Heart Rhythm 17(9):1463–1471

    Article  Google Scholar 

  10. Center for Disease Control (2021) Post COVID conditions

    Google Scholar 

  11. Rroku A, Kottwitz J, Heidecker B (2020) Update on myocarditis – what we know so far and where we may be heading. Eur Heart J Acute Cardiovasc Care 10(4):2048872620910109–2048872620910467

    Google Scholar 

  12. National Institute for Health (2021) Coronavirus and the Nervous System

    Google Scholar 

  13. Legrand M, Bell S, Forni L, Joannidis M, Koyner JL, Liu K, et al (2021) Pathophysiology of COVID-19-associated acute kidney injury. Nat Rev Nephrol 17:751–64

    Google Scholar 

  14. Weng J, Li Y, Li J, Shen L, Zhu L, Liang Y et al (2021) Gastrointestinal sequelae 90 days after discharge for COVID-19. Lancet Gastroenterol Hepatol 6(5):344

    Article  Google Scholar 

  15. Al-Aly Z, Xie Y, Bowe B (2021) High-dimensional characterization of post-acute sequelae of COVID-19. Lancet Digit Health 3(6):E330

    Article  Google Scholar 

  16. Makic MBF (2016) Recovery after ICU discharge: post–intensive care syndrome. J Perianesth Nurs 31(2):172–174

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Amanda Bergeron .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Bergeron, A. (2022). Long-Term Sequalae of COVID-19 Infection. In: Bergeron, A., Perkins, R., Ingebretson, E., Holifield, L. (eds) Principles in Nursing Practice in the Era of COVID-19. Springer, Cham. https://doi.org/10.1007/978-3-030-94740-8_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-94740-8_7

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-94739-2

  • Online ISBN: 978-3-030-94740-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics