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The Role of Preoperative Androgen Stimulation in the Management of Hypospadias

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Hypospadias Surgery

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Abstract

The role of preoperative androgen stimulation (PAS) in hypospadias remains controversial. The published literature is of low quality and lacks standardized reporting of important patient and surgical details. Very few randomized controlled studies recommended the judicious use of PAS in distal hypospadias. The majority of surgeons tend to use PAS in proximal hypospadias with small glans and/or narrow urethral plate. Most studies agree the PAS increases the size of the penis but vary on its role in outcome. Side effects have been reported with significant heterogenicity. Further research is needed to determine whether PAS improves surgical outcome.

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Abbreviations

DHT:

Dihydrotestosterone

hCG:

Human chorionic gonadotropin

PAS:

Preoperative androgen stimulation

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Authors and Affiliations

  1. Departments of Urology and Paediatric Surgery, Beacon Hospital and UCD School of Medicine and Medical Sciences, Dublin, Ireland

    Fardod O’Kelly

  2. Division of Urology, Department of Surgery, McMaster Children’s Hospital, McMaster University, Hamilton, Ontario, Canada

    Luis H. Braga

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  1. Fardod O’Kelly
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  2. Luis H. Braga
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Correspondence to Luis H. Braga .

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Editors and Affiliations

  1. Hypospadias Center and Pediatric Surgery Department, Sana Klinikum Offenbach, Academic Teaching Hospital of the Johann Wolfgang Goethe University, Offenbach, Frankfurt, Germany

    Ahmed T. Hadidi

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O’Kelly, F., Braga, L.H. (2022). The Role of Preoperative Androgen Stimulation in the Management of Hypospadias. In: Hadidi, A.T. (eds) Hypospadias Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-94248-9_13

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  • DOI: https://doi.org/10.1007/978-3-030-94248-9_13

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