Skip to main content

Management of Concussion and Persistent Post-concussion Symptoms

  • Chapter
  • First Online:
Tackling the Concussion Epidemic

Abstract

While the majority of patients who sustain a concussion will recover completely, a significant number will experience persistent symptoms beyond the expected period of recovery of two weeks in adults and four weeks in children. Up to 10–30% of patients will continue to experience symptoms three-months post-concussion. Early management strategies to facilitate recovery include an initial assessment by a medical professional to confirm diagnosis and rule out more serious injury, and a recommendation of relative physical and cognitive rest for the initial 24–48 hours post-concussion, after which symptom-limited activity can be resumed as tolerated. While most individuals will recover spontaneously, early referral to an interdisciplinary team of clinicians with concussion expertise may be indicated for individuals who are at risk of persistent or escalating symptoms. Early clinical management should focus on symptoms that are readily managed and will have a significant impact, typically sleep disturbance, post-traumatic headache and mood. Ongoing management may be required for functionally-limiting symptoms that are multifactorial in origin, including fatigue, environmental sensitivity, dizziness/vestibular impairment, and vision impairment. Emerging research supports a multifaceted approach to symptoms management that includes education, cervical rehabilitation, vestibular therapy, cognitive behavioral therapy, and sub-symptom threshold exercise.

This chapter will address recommendations regarding the assessment and management of persistent post-concussion symptoms. First, the diagnosis of concussion and expectations for normal recovery will be discussed. Second, risk factors for prolonged recovery and recommendations for early referral to interdisciplinary care to prevent persistent symptoms will be presented. Finally, the assessment and management of common persistent post-concussion symptoms will be discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Silverberg ND, Iaccarino MA, Panenka WJ, Iverson GL, McCulloch KL, Dams-O’Connor K, et al. Management of concussion and mild traumatic brain injury: a synthesis of practice guidelines. Arch Phys Med Rehabil. 2020;101(2):382–93.

    PubMed  Google Scholar 

  2. McCrory P, Meeuwisse W, Dvořák J, Aubry M, Bailes J, Broglio S, et al. Consensus statement on concussion in sport-the 5th international conference on concussion in sport held in Berlin, October 2016. Br J Sports Med. 2017;51(11):838–47.

    PubMed  Google Scholar 

  3. Veterans Affairs/Department of Defense. Management of Concussion-Mild Traumatic Brain Injury (MTBI) clinical practice guidelines [Internet]. VA/DoD Clinical Practice Guidelines. 2016 [cited 2018 Jun 11]. Available from: https://www.healthquality.va.gov/guidelines/rehab/mtbi/.

  4. Ontario Neurotrauma Foundation. Guidelines on diagnosing and managing pediatric concussion [Internet]. 2014 [cited 2018 Jun 11]. Available from: https://web.archive.org/web/20180416105612/http://onf.org/documents/guidelines-diagnosing-and-managing-pediatric-concussion.

  5. Ontario Neurotrauma Foundation. Guidelines for concussion/mild traumatic brain injury & persistent symptoms. 2018 [cited 2021 Aug 17]. Available from: https://braininjuryguidelines.org/concussion/.

  6. Harmon KG, Clugston JR, Dec K, Hainline B, Herring S, Kane SF, et al. American Medical Society for Sports Medicine position statement on concussion in sport. Br J Sports Med. 2019;53(4):213–25.

    PubMed  Google Scholar 

  7. The New England Journal of Medicine. Concussion: guidelines and best practices [Internet]. Massachusetts Medical Society; [cited 2021 Aug 17]. Available from: https://web.archive.org/web/2015*/collections.nejm.org.

  8. Reed N, Zemek R, Dawson J, Ledoux AA, Provvidenza C, Paniccia M, et al. Living guideline for diagnosing and managing pediatric concussion. Toronto [Internet]. Ontario Neurotrauma Foundation; [cited 2021 Aug 17]. Available from: https://braininjuryguidelines.org/pediatricconcussion/.

  9. Lumba-Brown A. Centers for Disease Control and Prevention guideline on the diagnosis and management of mild traumatic brain injury among children. JAMA Pediatr. 2018;172:e182853.

    PubMed  PubMed Central  Google Scholar 

  10. American Association of Neurological Surgeons. Concussion [Internet]. [cited 2021 Aug 17]. Available from: https://www.aans.org/en/Patients/Neurosurgical-Conditions%20and%20Treatments/Concussion.

  11. Ferdinand Pennock K, McKenzie B, McClemont Steacy L, Mainwaring L. Under-reporting of sport-related concussions by adolescent athletes: a systematic review. Int Rev Sport Exerc Psychol. 2020;6:1–27.

    Google Scholar 

  12. The Concussion in Sports Group. Sport concussion assessment tool - 5th edition. Br J Sports Med. 2017 Apr 26;bjsports-2017-097506SCAT5.

    Google Scholar 

  13. King NS, Crawford S, Wenden FJ, Moss NE, Wade DT. The Rivermead Post Concussion Symptoms Questionnaire: a measure of symptoms commonly experienced after head injury and its reliability. J Neurol. 1995;242(9):587–92.

    CAS  PubMed  Google Scholar 

  14. Lovell MR, Collins MW. Neuropsychological assessment of the college football player. J Head Trauma Rehabil. 1998;13(2):9–26.

    CAS  PubMed  Google Scholar 

  15. Stiell IG, Wells GA, Vandemheen K, Clement C, Lesiuk H, Laupacis A, et al. The Canadian CT Head Rule for patients with minor head injury. Lancet Lond Engl. 2001;357(9266):1391–6.

    CAS  Google Scholar 

  16. Kuppermann N, Holmes JF, Dayan PS, Hoyle JD, Atabaki SM, Holubkov R, et al. Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. Lancet Lond Engl. 2009;374(9696):1160–70.

    Google Scholar 

  17. Osmond MH, Klassen TP, Wells GA, Correll R, Jarvis A, Joubert G, et al. CATCH: a clinical decision rule for the use of computed tomography in children with minor head injury. CMAJ Can Med Assoc J J Assoc Medicale Can. 2010;182(4):341–8.

    Google Scholar 

  18. Concussion Awareness Training Tool. Concussion resources for parents & caregivers [Internet]. [cited 2021 Aug 17]. Available from: https://webcache.googleusercontent.com/search?q=cache:YIgqBkX2wN0J:https://cattonline.com/wp-content/uploads/2021/05/Concussion-Resources-for-Parents-and-Caregivers-CATT-V3-April-2021-.pdf+&cd=1&hl=en&ct=clnk&gl=ca.

  19. Silverberg ND, Iverson GL. Etiology of the post-concussion syndrome: physiogenesis and psychogenesis revisited. NeuroRehabilitation. 2011;29(4):317–29.

    PubMed  Google Scholar 

  20. Preece MHW, Geffen GM, Horswill MS. Return-to-driving expectations following mild traumatic brain injury. Brain Inj. 2013;27(1):83–91.

    PubMed  Google Scholar 

  21. Preece MHW, Horswill MS, Geffen GM. Driving after concussion: the acute effect of mild traumatic brain injury on drivers’ hazard perception. Neuropsychology. 2010;24(4):493–503.

    PubMed  Google Scholar 

  22. Baker A, Unsworth CA, Lannin NA. Fitness-to-drive after mild traumatic brain injury: mapping the time trajectory of recovery in the acute stages post injury. Accid Anal Prev. 2015;79:50–5.

    PubMed  Google Scholar 

  23. Theadom A, Parag V, Dowell T, McPherson K, Starkey N, Barker-Collo S, et al. Persistent problems 1 year after mild traumatic brain injury: a longitudinal population study in New Zealand. Br J Gen Pract J R Coll Gen Pract. 2016;66(642):e16–23.

    Google Scholar 

  24. Zemek R, Barrowman N, Freedman SB, Gravel J, Gagnon I, McGahern C, et al. Clinical risk score for persistent postconcussion symptoms among children with acute concussion in the ED. JAMA. 2016;315(10):1014–25.

    CAS  PubMed  Google Scholar 

  25. Varner C, Thompson C, de Wit K, Borgundvaag B, Houston R, McLeod S. Predictors of persistent concussion symptoms in adults with acute mild traumatic brain injury presenting to the emergency department. CJEM. 2021;23(3):365–73.

    PubMed  Google Scholar 

  26. Silverberg ND, Gardner AJ, Brubacher JR, Panenka WJ, Li JJ, Iverson GL. Systematic review of multivariable prognostic models for mild traumatic brain injury. J Neurotrauma. 2015;32(8):517–26.

    PubMed  Google Scholar 

  27. Cnossen MC, van der Naalt J, Spikman JM, Nieboer D, Yue JK, Winkler EA, et al. Prediction of persistent post-concussion symptoms after mild traumatic brain injury. J Neurotrauma. 2018;35(22):2691–8.

    PubMed  Google Scholar 

  28. Langer LK, Alavinia SM, Lawrence DW, Munce SEP, Kam A, Tam A, et al. Prediction of risk of prolonged post-concussion symptoms: derivation and validation of the TRICORDRR (Toronto Rehabilitation Institute Concussion Outcome Determination and Rehab Recommendations) score. PLoS Med. 2021;18(7):e1003652.

    PubMed  PubMed Central  Google Scholar 

  29. Ponsford J, Willmott C, Rothwell A, Cameron P, Kelly A-M, Nelms R, et al. Impact of early intervention on outcome following mild head injury in adults. J Neurol Neurosurg Psychiatry. 2002;73(3):330–2.

    CAS  PubMed  PubMed Central  Google Scholar 

  30. Thibault-Halman G, Fenerty L, Taylor P, Kureshi N, Walling S, Clarke D. P.016 early telephone follow-up for traumatic brain injury patients using the Rivermead post-concussion symptoms questionnaire. Can J Neurol Sci J Can Sci Neurol. 2017;44(S2):S17–8.

    Google Scholar 

  31. Silverberg ND, Iverson GL. Is rest after concussion “the best medicine?”: recommendations for activity resumption following concussion in athletes, civilians, and military service members. J Head Trauma Rehabil. 2013;28(4):250–9.

    PubMed  Google Scholar 

  32. Leddy JJ, Haider MN, Ellis M, Willer BS. Exercise is medicine for concussion. Curr Sports Med Rep. 2018;17(8):262–70.

    PubMed  PubMed Central  Google Scholar 

  33. Leddy JJ, Willer B. Use of graded exercise testing in concussion and return-to-activity management. Curr Sports Med Rep. 2013;12(6):370–6.

    PubMed  Google Scholar 

  34. McIntyre M, Kempenaar A, Amiri M, Alavinia SM, Kumbhare D. The role of subsymptom threshold aerobic exercise for persistent concussion symptoms in patients with postconcussion syndrome: a systematic review. Am J Phys Med Rehabil. 2020;99(3):257–64.

    PubMed  Google Scholar 

  35. Ontario Neurotrauma Foundation. Standards for post-concussion care [Internet]. 2017 [cited 2021 Aug 17]. Available from: https://concussionsontario.org/wp-content/uploads/2017/06/ONF-Standards-for-Post-Concussion-Care-June-8-2017.pdf.

  36. Concussions Ontario. Standards for high quality post-concussion services and concussion clinics [Internet]. [cited 2021 Aug 17]. Available from: http://concussionsontario.org/healthcareprofessionals/standards/standards-for-high-quality-post-concussion-services-and-concussion-clinics/.

  37. Concussions Ontario. Referral indicators [Internet]. [cited 2021 Aug 17]. Available from: https://concussionsontario.org/healthcareprofessionals/standards/tools-resources/referral-indicators/.

  38. Sady MD, Vaughan CG, Gioia GA. Psychometric characteristics of the postconcussion symptom inventory in children and adolescents. Arch Clin Neuropsychol Off J Natl Acad Neuropsychol. 2014;29(4):348–63.

    Google Scholar 

  39. Van Ierssel J, Sveistrup H, Marshall S, Graham I. The concussion recovery questionnaire (CORE-Q): conceptual model development and item generation of a concussion-specific measure of functional status. Brain Inj. 2020;34(5):619–29.

    PubMed  Google Scholar 

  40. Dwyer B, Katz DI. Postconcussion syndrome. In: Handbook of clinical neurology [Internet]. Elsevier; 2018. p. 163–78. Available from: https://linkinghub.elsevier.com/retrieve/pii/B9780444639547000173.

  41. Lagacé-Legendre C, Boucher V, Robert S, Tardif P-A, Ouellet M-C, de Guise E, et al. Persistent postconcussion symptoms: an expert consensus-based definition using the Delphi method. J Head Trauma Rehabil. 2021;36(2):96–102.

    PubMed  Google Scholar 

  42. Iverson GL, McCracken LM. “Postconcussive” symptoms in persons with chronic pain. Brain Inj. 1997;11(11):783–90.

    CAS  PubMed  Google Scholar 

  43. Iverson GL, Lange RT. Examination of “postconcussion-like” symptoms in a healthy sample. Appl Neuropsychol. 2003;10(3):137–44.

    PubMed  Google Scholar 

  44. McCrea M, Iverson GL, McAllister TW, Hammeke TA, Powell MR, Barr WB, et al. An integrated review of recovery after mild traumatic brain injury (MTBI): implications for clinical management. Clin Neuropsychol. 2009;23(8):1368–90.

    PubMed  Google Scholar 

  45. Voormolen DC, Cnossen MC, Polinder S, Gravesteijn BY, Von Steinbuechel N, Real RGL, et al. Prevalence of post-concussion-like symptoms in the general population in Italy, the Netherlands and the United Kingdom. Brain Inj. 2019;33(8):1078–86.

    PubMed  Google Scholar 

  46. Ruff RM, Weyer JC. Myths and mild traumatic brain injury. Psychol Inj Law. 2009;2(1):34–42.

    Google Scholar 

  47. Ruff RM. Mild traumatic brain injury and neural recovery: rethinking the debate. Gentry T, editor. NeuroRehabilitation. 2011;28(3):167–80.

    PubMed  Google Scholar 

  48. Hiploylee C, Dufort PA, Davis HS, Wennberg RA, Tartaglia MC, Mikulis D, et al. Longitudinal study of postconcussion syndrome: not everyone recovers. J Neurotrauma. 2017;34(8):1511–23.

    PubMed  PubMed Central  Google Scholar 

  49. Pinner M, Børgensen SE, Jensen R, Birket-Smith M, Gade A, Riis JO. Consensus-driven guidelines regarding commotio cerebri (Konsensusrapport om commotio cerebri (hjernerystelse) og det postcommotionelle syndrom). 2003:1–82.

    Google Scholar 

  50. Hou R, Moss-Morris R, Peveler R, Mogg K, Bradley BP, Belli A. When a minor head injury results in enduring symptoms: a prospective investigation of risk factors for postconcussional syndrome after mild traumatic brain injury. J Neurol Neurosurg Psychiatry. 2012;83(2):217–23.

    PubMed  Google Scholar 

  51. Nolin P, Villemure R, Heroux L. Determining long-term symptoms following mild traumatic brain injury: method of interview affects self-report. Brain Inj. 2006;20(11):1147–54.

    CAS  PubMed  Google Scholar 

  52. Sawchyn JM, Brulot MM, Strauss E. Note on the use of the postconcussion syndrome checklist. Arch Clin Neuropsychol Off J Natl Acad Neuropsychol. 2000;15(1):1–8.

    CAS  Google Scholar 

  53. Silverberg ND, Panenka WJ, Iverson GL. Work productivity loss after mild traumatic brain injury. Arch Phys Med Rehabil. 2018;99(2):250–6.

    PubMed  Google Scholar 

  54. Toronto Rehabilitation Institute [Internet]. Available from: https://www.uhn.ca/TorontoRehab.

  55. Gladstone J. From psychoneurosis to ICHD-2: an overview of the state of the art in post-traumatic headache. Headache. 2009;49(7):1097–111.

    PubMed  Google Scholar 

  56. Dikmen S, Machamer J, Fann JR, Temkin NR. Rates of symptom reporting following traumatic brain injury. J Int Neuropsychol Soc JINS. 2010;16(3):401–11.

    PubMed  Google Scholar 

  57. Lew HL, Lin P-H, Fuh J-L, Wang S-J, Clark DJ, Walker WC. Characteristics and treatment of headache after traumatic brain injury: a focused review. Am J Phys Med Rehabil. 2006;85(7):619–27.

    PubMed  Google Scholar 

  58. Lew HL, Poole JH, Guillory SB, Salerno RM, Leskin G, Sigford B. Persistent problems after traumatic brain injury: the need for long-term follow-up and coordinated care. J Rehabil Res Dev. 2006;43(2):vii–x.

    PubMed  Google Scholar 

  59. International Headache Society. International classification of headache disorders 3rd edition [Internet]. [cited 2021 Aug 17]. Available from: https://www.ichd-3.org/.

  60. Parachute. Concussion guide for athletes [Internet]. [cited 2021 Aug 17]. Available from: https://parachute.ca/wp-content/uploads/2019/06/Concussion-Guide-for-Athletes.pdf.

  61. Diener H-C, Limmroth V. Medication-overuse headache: a worldwide problem. Lancet Neurol. 2004;3(8):475–83.

    PubMed  Google Scholar 

  62. Ontario Neurotrauma Foundation. Guideline for concussion/mild traumatic brain injury & prolonged symptoms 3rd Edition, for adults over 18 years of age - Appendix 6.7 - Prophylactic Therapy [Internet]. [cited 2021 Aug 17]. Available from: https://braininjuryguidelines.org/concussion/.

  63. Wiseman-Hakes C, Colantonio A, Gargaro J. Sleep and wake disorders following traumatic brain injury: a systematic review of the literature. Crit Rev Phys Rehabil Med. 2009;21(3–4):317–74.

    Google Scholar 

  64. Castriotta RJ, Wilde MC, Lai JM, Atanasov S, Masel BE, Kuna ST. Prevalence and consequences of sleep disorders in traumatic brain injury. J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med. 2007;3(4):349–56.

    Google Scholar 

  65. Ouellet M-C, Beaulieu-Bonneau S, Morin CM. Insomnia in patients with traumatic brain injury: frequency, characteristics, and risk factors. J Head Trauma Rehabil. 2006;21(3):199–212.

    PubMed  Google Scholar 

  66. Wiseman-Hakes C, Murray B, Moineddin R, Rochon E, Cullen N, Gargaro J, et al. Evaluating the impact of treatment for sleep/wake disorders on recovery of cognition and communication in adults with chronic TBI. Brain Inj. 2013;27(12):1364–76.

    PubMed  PubMed Central  Google Scholar 

  67. Chaput G, Giguère J-F, Chauny J-M, Denis R, Lavigne G. Relationship among subjective sleep complaints, headaches, and mood alterations following a mild traumatic brain injury. Sleep Med. 2009;10(7):713–6.

    PubMed  Google Scholar 

  68. Chan LG, Feinstein A. Persistent sleep disturbances independently predict poorer functional and social outcomes 1 year after mild traumatic brain injury. J Head Trauma Rehabil. 2015;30(6):E67–75.

    PubMed  Google Scholar 

  69. Ontario Neurotrauma Foundation. Guideline for concussion/mild traumatic brain injury & persistent symptoms 3rd Edition, for adults over 18 years of age - sleep-wake disturbances [Internet]. [cited 2021 Aug 17]. Available from: https://braininjuryguidelines.org/concussion/.

  70. Ouellet M-C, Morin CM. Cognitive behavioral therapy for insomnia associated with traumatic brain injury: a single-case study. Arch Phys Med Rehabil. 2004;85(8):1298–302.

    PubMed  Google Scholar 

  71. Ouellet M-C, Morin CM. Efficacy of cognitive-behavioral therapy for insomnia associated with traumatic brain injury: a single-case experimental design. Arch Phys Med Rehabil. 2007;88(12):1581–92.

    PubMed  Google Scholar 

  72. Espie CA, MacMahon KMA, Kelly H-L, Broomfield NM, Douglas NJ, Engleman HM, et al. Randomized clinical effectiveness trial of nurse-administered small-group cognitive behavior therapy for persistent insomnia in general practice. Sleep. 2007;30(5):574–84.

    PubMed  Google Scholar 

  73. Meares S, Shores EA, Batchelor J, Baguley IJ, Chapman J, Gurka J, et al. The relationship of psychological and cognitive factors and opioids in the development of the postconcussion syndrome in general trauma patients with mild traumatic brain injury. J Int Neuropsychol Soc JINS. 2006;12(6):792–801.

    PubMed  Google Scholar 

  74. Ponsford J, Willmott C, Rothwell A, Cameron P, Kelly AM, Nelms R, et al. Factors influencing outcome following mild traumatic brain injury in adults. J Int Neuropsychol Soc JINS. 2000;6(5):568–79.

    CAS  PubMed  Google Scholar 

  75. Ontario Neurotrauma Foundation. Guideline for concussion/mild traumatic brain injury & persistent symptoms 3rd Edition, for adults over 18 years of age - mental health disorders [Internet]. [cited 2021 Aug 17]. Available from: https://braininjuryguidelines.org/concussion/.

  76. Mollayeva T, Kendzerska T, Mollayeva S, Shapiro CM, Colantonio A, Cassidy JD. A systematic review of fatigue in patients with traumatic brain injury: the course, predictors and consequences. Neurosci Biobehav Rev. 2014;47:684–716.

    PubMed  Google Scholar 

  77. Cantor JB, Ashman T, Gordon W, Ginsberg A, Engmann C, Egan M, et al. Fatigue after traumatic brain injury and its impact on participation and quality of life. J Head Trauma Rehabil. 2008;23(1):41–51.

    PubMed  Google Scholar 

  78. Bay E, de-Leon MB. Chronic stress and fatigue-related quality of life after mild to moderate traumatic brain injury. J Head Trauma Rehabil. 2011;26(5):355–63.

    PubMed  PubMed Central  Google Scholar 

  79. Englander J, Bushnik T, Oggins J, Katznelson L. Fatigue after traumatic brain injury: association with neuroendocrine, sleep, depression and other factors. Brain Inj. 2010;24(12):1379–88.

    PubMed  Google Scholar 

  80. Bushnik T, Englander J, Katznelson L. Fatigue after TBI: association with neuroendocrine abnormalities. Brain Inj. 2007;21(6):559–66.

    PubMed  Google Scholar 

  81. Schnieders J, Willemsen D, de Boer H. Factors contributing to chronic fatigue after traumatic brain injury. J Head Trauma Rehabil. 2012;27(6):404–12.

    PubMed  Google Scholar 

  82. Sullivan KA, Blaine H, Kaye S-A, Theadom A, Haden C, Smith SS. A systematic review of psychological interventions for sleep and fatigue after mild traumatic brain injury. J Neurotrauma. 2018;35(2):195–209.

    PubMed  Google Scholar 

  83. Northern Lincolnshire and Goole National Health Institute. Fatigue: “Pacing” as a Strategy [Internet]. [cited 2021 Aug 17]. Available from: https://www.nlg.nhs.uk/content/uploads/2015/09/IFP-0875-Fatigue-Pacing-as-a-Strategy.pdf.

  84. Zhang W-T, Wang Y-F. Efficacy of methylphenidate for the treatment of mental sequelae after traumatic brain injury. Medicine (Baltimore). 2017;96(25):e6960.

    CAS  Google Scholar 

  85. Johansson B, Wentzel A-P, Andréll P, Rönnbäck L, Mannheimer C. Long-term treatment with methylphenidate for fatigue after traumatic brain injury. Acta Neurol Scand. 2017;135(1):100–7.

    CAS  PubMed  Google Scholar 

  86. Iaccarino MA, Philpotts LL, Zafonte R, Biederman J. Stimulant use in the management of mild traumatic brain injury: a qualitative literature review. J Atten Disord. 2020;24(2):309–17.

    PubMed  Google Scholar 

  87. Wylie GR, Freeman K, Thomas A, Shpaner M, OKeefe M, Watts R, et al. Cognitive improvement after mild traumatic brain injury measured with functional neuroimaging during the acute period. PLoS One. 2015;10(5):e0126110.

    PubMed  PubMed Central  Google Scholar 

  88. Rabinowitz AR, Levin HS. Cognitive sequelae of traumatic brain injury. Psychiatr Clin North Am. 2014;37(1):1–11.

    PubMed  PubMed Central  Google Scholar 

  89. Metting Z, Rödiger LA, Stewart RE, Oudkerk M, De Keyser J, van der Naalt J. Perfusion computed tomography in the acute phase of mild head injury: regional dysfunction and prognostic value. Ann Neurol. 2009;66(6):809–16.

    PubMed  Google Scholar 

  90. McInnes K, Friesen CL, MacKenzie DE, Westwood DA, Boe SG. Mild traumatic brain injury (mTBI) and chronic cognitive impairment: a scoping review. PLoS One. 2017;12(4):e0174847.

    PubMed  PubMed Central  Google Scholar 

  91. Nordström A, Edin BB, Lindström S, Nordström P. Cognitive function and other risk factors for mild traumatic brain injury in young men: nationwide cohort study. BMJ. 2013;346:f723.

    PubMed  Google Scholar 

  92. Binder LM, Rohling ML, Larrabee GJ. A review of mild head trauma. Part I: meta-analytic review of neuropsychological studies. J Clin Exp Neuropsychol. 1997;19(3):421–31.

    CAS  PubMed  Google Scholar 

  93. Schretlen DJ, Shapiro AM. A quantitative review of the effects of traumatic brain injury on cognitive functioning. Int Rev Psychiatry Abingdon Engl. 2003;15(4):341–9.

    Google Scholar 

  94. Frencham KAR, Fox AM, Maybery MT. Neuropsychological studies of mild traumatic brain injury: a meta-analytic review of research since 1995. J Clin Exp Neuropsychol. 2005;27(3):334–51.

    PubMed  Google Scholar 

  95. Belanger HG, Curtiss G, Demery JA, Lebowitz BK, Vanderploeg RD. Factors moderating neuropsychological outcomes following mild traumatic brain injury: a meta-analysis. J Int Neuropsychol Soc JINS. 2005;11(3):215–27.

    PubMed  Google Scholar 

  96. Oldenburg C, Lundin A, Edman G, Nygren-de Boussard C, Bartfai A. Cognitive reserve and persistent post-concussion symptoms—a prospective mild traumatic brain injury (mTBI) cohort study. Brain Inj. 2016;30(2):146–55.

    PubMed  Google Scholar 

  97. Bigler ED. Neuropsychology and clinical neuroscience of persistent post-concussive syndrome. J Int Neuropsychol Soc. 2008;14(1):1–22.

    PubMed  Google Scholar 

  98. Cooper DB, Bunner AE, Kennedy JE, Balldin V, Tate DF, Eapen BC, et al. Treatment of persistent post-concussive symptoms after mild traumatic brain injury: a systematic review of cognitive rehabilitation and behavioral health interventions in military service members and veterans. Brain Imaging Behav. 2015;9(3):403–20.

    PubMed  Google Scholar 

  99. Brunger H, Ogden J, Malia K, Eldred C, Terblanche R, Mistlin A. Adjusting to persistent post-concussive symptoms following mild traumatic brain injury and subsequent psycho-educational intervention: a qualitative analysis in military personnel. Brain Inj. 2014;28(1):71–80.

    PubMed  Google Scholar 

  100. Broshek DK, De Marco AP, Freeman JR. A review of post-concussion syndrome and psychological factors associated with concussion. Brain Inj. 2015;29(2):228–37.

    PubMed  Google Scholar 

  101. Ontario Neurotrauma Foundation. Guideline for concussion/mild traumatic brain injury & persistent symptoms 3rd edition, for adults over 18 years of age - cognitive difficulties [Internet]. [cited 2021 Aug 17]. Available from: https://braininjuryguidelines.org/concussion/.

  102. Cullen KE. The vestibular system: multimodal integration and encoding of self-motion for motor control. Trends Neurosci. 2012;35(3):185–96.

    CAS  PubMed  PubMed Central  Google Scholar 

  103. Brodsky JR, Shoshany TN, Lipson S, Zhou G. Peripheral vestibular disorders in children and adolescents with concussion. Otolaryngol--Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg. 2018;159(2):365–70.

    Google Scholar 

  104. Haripriya GR, Mary P, Dominic M, Goyal R, Sahadevan A. Incidence and treatment outcomes of post traumatic BPPV in traumatic brain injury patients. Indian J Otolaryngol Head Neck Surg. 2018;70(3):337–41.

    CAS  PubMed  PubMed Central  Google Scholar 

  105. Hoffer ME, Gottshall KR, Moore R, Balough BJ, Wester D. Characterizing and treating dizziness after mild head trauma. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol. 2004;25(2):135–8.

    Google Scholar 

  106. Wang A, Zhou G, Kawai K, O’Brien M, Shearer AE, Brodsky JR. Benign paroxysmal positional vertigo in children and adolescents with concussion. Sports Health. 2021;13(4):380–6.

    PubMed  PubMed Central  Google Scholar 

  107. Staab JP, Eckhardt-Henn A, Horii A, Jacob R, Strupp M, Brandt T, et al. Diagnostic criteria for persistent postural-perceptual dizziness (PPPD): consensus document of the committee for the classification of vestibular disorders of the Bárány Society. J Vestib Res Equilib Orientat. 2017;27(4):191–208.

    Google Scholar 

  108. Popkirov S, Stone J, Holle-Lee D. Treatment of persistent postural-perceptual dizziness (PPPD) and related disorders. Curr Treat Options Neurol. 2018;20(12):50.

    PubMed  Google Scholar 

  109. Herdman S, Clendaniel RA, editors. Vestibular rehabilitation [Internet]. 4th edn. Philadelphia: F. A. Davis Company; 2014. p. 630. (Contemporary perspectives in rehabilitation). Available from: https://www.fadavis.com/product/physical-therapy-vestibular-rehabilitation-herdman-4.

  110. Corwin DJ, Wiebe DJ, Zonfrillo MR, Grady MF, Robinson RL, Goodman AM, et al. Vestibular deficits following youth concussion. J Pediatr. 2015;166(5):1221–5.

    PubMed  PubMed Central  Google Scholar 

  111. Jacobson GP, Newman CW. The development of the dizziness handicap inventory. Arch Otolaryngol Head Neck Surg. 1990;116(4):424–7.

    CAS  PubMed  Google Scholar 

  112. Bell DR, Guskiewicz KM, Clark MA, Padua DA. Systematic review of the balance error scoring system. Sports Health Multidiscip Approach. 2011;3(3):287–95.

    Google Scholar 

  113. Takacs J, Garland SJ, Carpenter MG, Hunt MA. Validity and reliability of the community balance and mobility scale in individuals with knee osteoarthritis. Phys Ther. 2014;94(6):866–74.

    PubMed  PubMed Central  Google Scholar 

  114. Schubert MC, Minor LB. Vestibulo-ocular physiology underlying vestibular hypofunction. Phys Ther. 2004;84(4):373–85.

    PubMed  Google Scholar 

  115. Murray DA, Meldrum D, Lennon O. Can vestibular rehabilitation exercises help patients with concussion? A systematic review of efficacy, prescription and progression patterns. Br J Sports Med. 2017;51(5):442–51.

    PubMed  Google Scholar 

  116. Bhattacharyya N, Gubbels SP, Schwartz SR, Edlow JA, El-Kashlan H, Fife T, et al. Clinical practice guideline: benign paroxysmal positional vertigo (Update). Otolaryngol--Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg. 2017;156(3_suppl):S1–47.

    Google Scholar 

  117. Prokopakis E, Vlastos IM, Tsagournisakis M, Christodoulou P, Kawauchi H, Velegrakis G. Canalith repositioning procedures among 965 patients with benign paroxysmal positional vertigo. Audiol Neurootol. 2013;18(2):83–8.

    CAS  PubMed  Google Scholar 

  118. McDonnell MN, Hillier SL. Vestibular rehabilitation for unilateral peripheral vestibular dysfunction. Cochrane ENT Group, editor. Cochrane Database Syst Rev [Internet]. 2015 Jan 13 [cited 2021 Aug 17]. Available from: https://doi.org/10.1002/14651858.CD005397.pub4.

  119. Alsalaheen BA, Whitney SL, Mucha A, Morris LO, Furman JM, Sparto PJ. Exercise prescription patterns in patients treated with vestibular rehabilitation after concussion. Physiother Res Int J Res Clin Phys Ther. 2013;18(2):100–8.

    Google Scholar 

  120. Aligene K, Lin E. Vestibular and balance treatment of the concussed athlete. NeuroRehabilitation. 2013;32(3):543–53.

    PubMed  Google Scholar 

  121. Akin FW, Davenport MJ. Validity and reliability of the Motion Sensitivity Test. J Rehabil Res Dev. 2003;40(5):415–21.

    PubMed  Google Scholar 

  122. Alsalaheen BA, Mucha A, Morris LO, Whitney SL, Furman JM, Camiolo-Reddy CE, et al. Vestibular rehabilitation for dizziness and balance disorders after concussion. J Neurol Phys Ther JNPT. 2010;34(2):87–93.

    PubMed  Google Scholar 

  123. Master CL, Master SR, Wiebe DJ, Storey EP, Lockyer JE, Podolak OE, et al. Vision and vestibular system dysfunction predicts prolonged concussion recovery in children. Clin J Sport Med Off J Can Acad Sport Med. 2018;28(2):139–45.

    Google Scholar 

  124. Cockerham GC, Goodrich GL, Weichel LED, Orcutt JC, Rizzo JF, Bower CKS, et al. Eye and visual function in traumatic brain injury. J Rehabil Res Dev. 2009;46(6):811.

    PubMed  Google Scholar 

  125. Lara F, Cacho P, García A, Megías R. General binocular disorders: prevalence in a clinic population. Ophthalmic Physiol Opt J Br Coll Ophthalmic Opt Optom. 2001;21(1):70–4.

    CAS  Google Scholar 

  126. Master CL, Scheiman M, Gallaway M, Goodman A, Robinson RL, Master SR, et al. Vision diagnoses are common after concussion in adolescents. Clin Pediatr (Phila). 2016;55(3):260–7.

    Google Scholar 

  127. Hunt AW, Mah K, Reed N, Engel L, Keightley M. Oculomotor-based vision assessment in mild traumatic brain injury: a systematic review. J Head Trauma Rehabil. 2016;31(4):252–61.

    PubMed  Google Scholar 

  128. Kapoor N, Ciuffreda KJ. Vision disturbances following traumatic brain injury. Curr Treat Options Neurol. 2002;4(4):271–80.

    PubMed  Google Scholar 

  129. Simpson-Jones ME, Hunt AW. Vision rehabilitation interventions following mild traumatic brain injury: a scoping review. Disabil Rehabil. 2019;41(18):2206–22.

    PubMed  Google Scholar 

  130. Ciufredda KJ, Ludlam DP. Conceptual model of optometric vision care in mild traumatic brain injury. J Behav Optom. 2011;22:10–2.

    Google Scholar 

  131. Military Health System. Assessment and management of visual dysfunction associated with mild traumatic brain injury - Department of Defense Clinical Recommendation [Internet]. [cited 2021 Aug 17]. Available from: https://health.mil/Reference-Center/Publications/2020/07/31/Assessment-and-Management-of-Visual-Dysfunction-Associated-with-Mild-TBI-Clinical-Recommendation.

  132. Rouse MW, Borsting EJ, Mitchell GL, Scheiman M, Cotter SA, Cooper J, et al. Validity and reliability of the revised convergence insufficiency symptom survey in adults. Ophthalmic Physiol Opt J Br Coll Ophthalmic Opt Optom. 2004;24(5):384–90.

    Google Scholar 

  133. Borsting EJ, Rouse MW, Mitchell GL, Scheiman M, Cotter SA, Cooper J, et al. Validity and reliability of the revised convergence insufficiency symptom survey in children aged 9 to 18 years. Optom Vis Sci Off Publ Am Acad Optom. 2003;80(12):832–8.

    Google Scholar 

  134. Pavlou M, Whitney SL, Alkathiry AA, Huett M, Luxon LM, Raglan E, et al. Visually induced dizziness in children and validation of the pediatric visually induced dizziness questionnaire. Front Neurol. 2017;8:656.

    PubMed  PubMed Central  Google Scholar 

  135. Mucha A, Collins MW, Elbin RJ, Furman JM, Troutman-Enseki C, DeWolf RM, et al. A brief vestibular/ocular motor screening (VOMS) assessment to evaluate concussions: preliminary findings. Am J Sports Med. 2014;42(10):2479–86.

    PubMed  PubMed Central  Google Scholar 

  136. Anzalone AJ, Blueitt D, Case T, McGuffin T, Pollard K, Garrison JC, et al. A positive vestibular/ocular motor screening (VOMS) is associated with increased recovery time after sports-related concussion in youth and adolescent athletes. Am J Sports Med. 2017;45(2):474–9.

    PubMed  Google Scholar 

  137. Snegireva N, Derman W, Patricios J, Welman KE. Eye tracking technology in sports-related concussion: a systematic review and meta-analysis. Physiol Meas. 2018;39(12):12TR01.

    CAS  PubMed  Google Scholar 

  138. Barton JJS, Ranalli PJ. Vision therapy: ocular motor training in mild traumatic brain injury. Ann Neurol. 2020;88(3):453–61.

    PubMed  Google Scholar 

  139. Dwyer B, Katz DI. Postconcussion syndrome. Handb Clin Neurol. 2018;158:163–78. https://doi.org/10.1016/B978-0-444-63954-7.00017-3.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shawn Marshall .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Marshall, S., van Ierssel, J. (2022). Management of Concussion and Persistent Post-concussion Symptoms. In: Schweizer, T.A., Baker, A.J. (eds) Tackling the Concussion Epidemic. Springer, Cham. https://doi.org/10.1007/978-3-030-93813-0_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-93813-0_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-93812-3

  • Online ISBN: 978-3-030-93813-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics