A 1-year-old infantile male patient presented to us with a 60-mm × 40-mm right ear and face superficial protuberant infantile hemangioma that appeared at birth growing steadily over time and then gradually developed 30-mm × 35-mm ulceration of the inferior half over the last 6 weeks. In his medical history, he had systemic steroid, oral propranolol and sirolimus drug medication. With the regression of the lesion that benefited from the treatment, discontinued the treatment and relapsed. Prednizolon 1.5 mg/kg/day and propranolol 3 mg/kg/day were restarted by our pediatric oncology department. Prednizolon was discontinued in outpatient clinic examinations 1 month later. And then 2 drops of 0.5% betoxalol solution was applied thrice daily over the entire lesion by our dermatology department. The ulcer complete healing was achieved by 3 month, leaving a whitish scar. At monthly outpatient clinic reviews, the child’s recorded vital signs ranged as follows: heart rate, 120–135 beats per minute; blood pressure, 80–96/55–73 mmHg; and random glucose, 5.6–8.2 mmol/l. Propranolol and 0.5% betoxolol solution were continued for 6 months, and there was no ulcer recurrence at 12 months after stopping treatment.
Keywords
- Hemangioma
- Propranolol
- Prednisolon
- Ulcer
- Beta blockers
- Pediatric cancer