Abstract
Squamous cell carcinoma (SCC) is a common malignancy in adults but are exceptionally rare in children. However, children with certain disease condition, for example, xeroderma pigmentosum (XP), a rare inherited disease, is highly susceptible to the development of skin malignancy including SCC.
We report a case of XP in an 18-years old boy with clinical symptoms of lentiginous spots in the sun-exposed area, accompanied by Squamous Cell Carcinoma (SCC) in the eye based on histopathological examination.
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References
Kaposi M, Hebra F. On diseases of the skin including exanthemata, vol. 3. London: New Sydenham Society; 1874. p. 252.
English JS, Swerdlow AJ. The risk of malignant melanoma, internal malignancy and mortality in XP patients. Br J Dermatol. 1987;117(4):457–61.
Ameri AH, Mooradian MJ, Emerick KS, et al. Immunotherapeutic strategies for cutaneous squamous cell carcinoma prevention in xeroderma pigmentosum. Br J Dermatol. 2019;181:1095.
Tabri F. Xeroderma pigmentosum with ocular squamous cell carcinoma—a case report. Int J Health Sci Res. 2019;9(1):296.
Sethi M, Lehmann AR, Fawcett H, et al. Patients with XP complementation groups C, E and V do not have abnormal sunburn reactions. Br J Dermatol. 2013;169:1279–87.
Kraemer KH, Lee MM, Scotto J. Xeroderma Pigmentosum: cutaneous, ocular and neurological abnormalities in 830 published cases. Arch Dermatol. 1987;123:241–50.
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Doanh, L.H., Van Thuong, N., Tirant, M. (2022). Periocular Squamous Cell Carcinoma in a Child with Xeroderma Pigmentosum. In: Satolli, F., Tirant, M., Wollina, U., Lotti, T.M. (eds) Clinical Cases in Pediatric Skin Cancers. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-93666-2_27
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DOI: https://doi.org/10.1007/978-3-030-93666-2_27
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