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A 33-Year-Old Woman with Brain Metastases of Unknown Origin and a Melanotic Lesion on the Scalp

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Clinical Cases in Scalp Disorders

Part of the book series: Clinical Cases in Dermatology ((CLIDADE))

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Abstract

Melanoma is the most fatal form of skin cancer. Scalp melanomas account for 7% of all melanomas. Hair loss, chronic sun damage and history of skin cancer are well-recognized risk factors for developing the scalp melanoma. Similarly, to cutaneous melanoma on the other areas, the scalp melanoma occurs mostly in the elderly, with average ages ranging from 50 to 67 years. Men are more commonly affected compared to women. The typical cutaneous melanoma occurs as an asymmetric macule or nodule with irregular borders, frequently with variations in color within the lesion. It may also presents as pink or red lesion (amelanotic melanoma). The scalp melanoma is characterized by more aggressive biologic behavior and is often diagnosed at a late stage. Histopathology is a gold standard diagnostic method in melanoma. Similarly to melanoma in other areas, wide local excision is recommended. Scalp melanoma in situ should be excised with 5 mm margins, melanoma <1 mm thick with 1 cm margins, melanoma 1–4 mm thick with 2 cm margins and melanoma >4 mm thick with 3 cm margins.

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References

  1. Kibbi N, Kluger H, Choi JN. Melanoma: clinical presentations. Cancer Treat Res. 2016;167:107–29.

    Article  Google Scholar 

  2. Leonardi GC, Falzone L, Salemi R, Zanghì A, Spandidos DA, McCubrey JA, et al. Cutaneous melanoma: from pathogenesis to therapy (review). Int J Oncol. 2018;52(4):1071–80.

    CAS  PubMed  PubMed Central  Google Scholar 

  3. Hartman RI, Lin JY. Cutaneous melanoma-a review in detection, staging, and management. Hematol Oncol Clin North Am. 2019;33(1):25–38.

    Article  Google Scholar 

  4. O'Neill CH, Scoggins CR. Melanoma. J Surg Oncol. 2019;120(5):873–81.

    Article  Google Scholar 

  5. Marghoob NG, Liopyris K, Jaimes N. Dermoscopy: a review of the structures that facilitate melanoma detection. J Am Osteopath Assoc. 2019;119(6):380–90.

    PubMed  Google Scholar 

  6. Saaiq M, Zalaudek I, Rao B, Lee Y, Rudnicka L, Czuwara J, et al. A brief synopsis on scalp melanoma. Dermatol Ther. 2020;33(4):e13795.

    Article  Google Scholar 

  7. Terakedis BE, Anker CJ, Leachman SA, Andtbacka RH, Bowen GM, Sause WT, et al. Patterns of failure and predictors of outcome in cutaneous malignant melanoma of the scalp. J Am Acad Dermatol. 2014;70(3):435–42.

    Article  Google Scholar 

  8. Marzuka AG, Book SE. Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management. Yale J Biol Med. 2015;88(2):167–79.

    PubMed  PubMed Central  Google Scholar 

  9. Hafner C, Vogt T. Seborrheic keratosis. J Dtsch Dermatol Ges. 2008;6(8):664–77.

    Article  Google Scholar 

  10. Tcheung WJ, Bellet JS, Prose NS, Cyr DD, Nelson KC. Clinical and dermoscopic features of 88 scalp naevi in 39 children. Br J Dermatol. 2011;165(1):137–43.

    Article  CAS  Google Scholar 

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Correspondence to Małgorzata Maj .

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Maj, M., Warszawik-Hendzel, O., Olszewska, M., Rudnicka, L. (2022). A 33-Year-Old Woman with Brain Metastases of Unknown Origin and a Melanotic Lesion on the Scalp. In: Waśkiel-Burnat, A., Sadoughifar, R., Lotti, T.M., Rudnicka, L. (eds) Clinical Cases in Scalp Disorders. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-93426-2_9

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  • DOI: https://doi.org/10.1007/978-3-030-93426-2_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-93425-5

  • Online ISBN: 978-3-030-93426-2

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