Abstract
The clinical tests of device based on Metal Insulator Semiconductor Field Effect (MIS-FE) gas sensor for Helicobacter pylori infection diagnostics (HP-infection) are done by breath test method. This method is based on detecting increase ammonia concentration in patient’s exhaled air after reception of carbamide water solution. The device’s stable operation is based on MIS-FE gas sensor’s high sensitivity to ammonia, sensor’s parameters stability as well as especially developed two channels gas sampling system.
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References
Plavnik, R.G., Nevmerzhitsky, V.I., Butorova, L.I., et al.: Use of breath testing in gastrointestinal disorders. Herald of North-Western State Med. Univ. Named After I I Mechnikov 12(1), 53–62 (2020). https://doi.org/10.17816/mechnikov26270
Rezaie, A., Buresi, M., Lembo, A., et al.: Hydrogen and methanebased breath testing in gastrointestinal disorders: the North American consensus. Am. J. Gastroenterol. 112(5), 775–784 (2017)
Robinson, K., Argent, R.H., et al.: The inflammatory and immune response to Helicobacter pylori infection. Best Pract. Res. Clin. Gastroenterol. 21, 237–259 (2007)
Tryapitsyn, A.V., Mal’kov, V.A.: The role and diagnostic value of the most common methods for diagnosing Helicobacter pylori infection. Herald of North-Western State Medical University Named After I I Mechnikov 11(4), 59–66 (2019)
Ivashkin, V.T., Mayev, I.V., Lapina, T.L., et al.: Treatment of helicobacter pylori infection: mainstream and innovations. Russ. J. Gastroenterol. Hepatol. Coloproctol. 27(4), 4–21 (2017). (In Russ.)
Saez, J., Belda, S., Santibáñez, M., et al.: Real-time PCR for diagnosing helicobacter pylori infection in patients with upper gastrointestinal bleeding: comparison with other classical diagnostic methods. J. Clin. Microbiol. 50, 3233–3237 (2012)
Gatta, L., Ricci, C., Tampieri, A., et al.: Accuracy of breath tests using low doses of 13C-urea to diagnose helicobacter pylori infection: a randomised controlled trial. Gut 55, 457–462 (2006)
http://www.membrapor.ch/sheet/Ammonia-Gas-Sensor-NH3-MR-100.pdf
Sanitary rules and regulations of the Russian Federation 1.2.3685-2, “Hygienic standards and requirements for ensuring the safety and (or) harmlessness to humans of environmental factors” at. https://docs.cntd.ru/document/573500115
Bolodurin, B.A., Korchak, V.Y., Litvinov, A.V., et al.: Comprehensive research on the response of MIS sensors of Pd-SiO2-Si and Pd-Ta2O5-SiO2-Si structures to various gases in air. Russ. J. Gener. Chem. 88(12), 2732–2739 (2018)
Kalinina, L.N., Litvinov, A.V., Nikolaev, I.N., et al.: MIS-field effect sensors for low concentration of H2S for environmental monitoring. Procedia Eng. 5, 1216–1219 (2010)
Samotaev, N., Litvinov, A., Etrekova, M., et al.: Prototype of nitro compound vapor and trace detector based on a capacitive MIS sensor. Sensors (Switzerland) 20(5), 1514 (2020)
Nikolaev, I., Litvinov, A., Yemelin, E.: A model of MIS sensors sensitivity mechanism to gas concentration. Sensors Syst. (Russ. Sci. J.) 7, 66–73 (2006)
Etrekova, M., Litvinov, A., Samotaev, N., Filipchuk, D., Oblov, K., Mikhailov, A.: Investigation of selectivity and reproducibility characteristics of gas capacitive MIS sensors. In: Velichko, E., Vinnichenko, M., Kapralova, V., Koucheryavy, Y. (eds.) International Youth Conference on Electronics, Telecommunications and Information Technologies. SPP, vol. 255, pp. 87–95. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-58868-7_10
Sukul, P., Schubert, J.K., Zanaty, K., et al.: Exhaled breath compositions under varying respiratory rhythms reflects ventilatory variations: translating breathomics towards respiratory medicine. Sci. Rep. 10(1), 14109 (2020)
Acknowledgment
This work was supported by a grant from the Russian Science Foundation No. 18–79-10230.
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Samotaev, N., Etrekova, M., Litvinov, A., Mikhailov, A. (2022). Selective Ammonia Detection by Field Effect Gas Sensor as an Instrumentation Basis for HP-Infection Primary Diagnosis. In: Tiginyanu, I., Sontea, V., Railean, S. (eds) 5th International Conference on Nanotechnologies and Biomedical Engineering. ICNBME 2021. IFMBE Proceedings, vol 87. Springer, Cham. https://doi.org/10.1007/978-3-030-92328-0_24
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DOI: https://doi.org/10.1007/978-3-030-92328-0_24
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