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Key Topics in Perinatal Mental Health pp 397–409Cite as

Biomarkers, Between Diagnosis and Prognosis

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Abstract

Perinatal depression is a heterogeneous disorder with differences in depression timing onset, symptomology, severity and treatment efficacy. The early individuation of mental health disease in women is mandatory to prevent a long duration of untreated illness, long-term consequences on offspring and maternal health effects in terms of mortality and morbidity.

Different biomarkers have been linked to perinatal depression, however no definitive conclusions can be done due to several variables involved in psychiatric disorder onset but also to the different methodological methods used in the studies.

The aim of this chapter is to outline the actual state of the art on biomarkers in perinatal depression, although being not comprehensive of all available data in literature, in order to search for reliable biomarkers able to early detect it and prevent its consequences on newborns.

Keywords

  • Perinatal depression
  • Biomarkers
  • Women’s mental health
  • Prevention

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Authors and Affiliations

  1. Department of Mental Health, ASST RHODENSE, Rho, Italy

    Marta Serati

  2. Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

    Massimiliano Buoli

  3. Department of Neurosciences and Mental Health, Fondazione IRCCS Ca’Granda Ospedale Maggiore Policlinico, Milan, Italy

    Massimiliano Buoli

  4. Department of Community Medicine, Mercer University School of Medicine, Macon, GA, USA

    Jennifer L. Barkin

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  1. Marta Serati
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  2. Massimiliano Buoli
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  3. Jennifer L. Barkin
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Correspondence to Marta Serati .

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Editors and Affiliations

  1. Department of Mental Health and Addiction Services, Niguarda Hospital, Milan, Italy

    Prof. Mauro Percudani

  2. Policentro Donna Ambulatory, Italian Marcé Society, Milan, Italy

    Dr. Alessandra Bramante

  3. Department of Mental Health and Addiction Services, Niguarda Hospital, Italian Marcé Society, Milan, Italy

    Dr. Valeria Brenna

  4. Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK

    Prof. Carmine Pariante

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Serati, M., Buoli, M., Barkin, J.L. (2022). Biomarkers, Between Diagnosis and Prognosis. In: Percudani, M., Bramante, A., Brenna, V., Pariante, C. (eds) Key Topics in Perinatal Mental Health. Springer, Cham. https://doi.org/10.1007/978-3-030-91832-3_26

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