Abstract
IgA pemphigus is a rare autoimmune bullous skin disease in adults as well as in children. Two major subtypes of IgA pemphigus are intraepidermal neutrophilic dermatosis and subcorneal pustular dermatosis. A definitive diagnosis of IgA pemphigus is made via immunofluorescence, presenting IgA deposits or circulating anti-IgA antibodies. Here we reported a 3-year-old boy with typical vesiculopustular eruptions and mucosa erosion for 4 months. His symptoms got better after a 3-week-use of oral sulfasalazine. This case illustrates that IgA pemphigus can also occur in the child at a young age. The anatomic distribution of lesions is not only confined to the intertriginous site. In addition, cells in infiltrating of IgA Pemphigus can be mixed neutrophils and eosinophils.
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Cheng, RH., Yu, H., Yao, ZR., Li, M. (2022). A Young Child with Vesiculopustular Eruptions and Mucosal Erosion. In: Arcangeli, F., Lotti, T.M. (eds) Clinical Cases in Early-Years Pediatric Dermatology. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-89089-6_9
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DOI: https://doi.org/10.1007/978-3-030-89089-6_9
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