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Heart Failure with Preserved Ejection Fraction

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Handbook of Outpatient Cardiology

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Abstract

Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent form of heart failure worldwide. This is in part by increasing prevalence of diabetes, hypertension, obesity, and aging of the general population. It remains a heterogeneous clinical entity, and diagnosis is challenging. Recent scores have been developed to provide us with properly derived and validated algorithms applicable in clinical practice and trials. Specific types of infiltrative cardiomyopathies should be identified since new medical treatments are available for specific conditions like cardiac amyloidosis. Clinical trials to date have been largely unsuccessful in identifying effective treatments that change the long-term outcome of the disease.

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Abbreviations

ACC:

American College of Cardiology

AHA:

American Heart Association

BNP:

Serum brain natriuretic peptide

ECG:

Electrocardiogram

FDA:

Food and Drug Administration

HF:

Heart failure

HFpEF:

Heart failure with preserved ejection fraction

HFrEF:

Heart failure with reduced ejection fraction

LV:

Left ventricle

LVEDP:

Left ventricular end-diastolic pressure

LVEF:

Left ventricular ejection fraction

mPCWP:

Mean pulmonary capillary wedge pressure

NT-proBNP:

N-terminal pro-brain natriuretic peptide

PASP:

Pulmonary artery systolic pressure

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Author information

Authors and Affiliations

  1. Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

    Nicolas Isaza

  2. Department of Medicine, Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

    Pablo A. Quintero

Authors
  1. Nicolas Isaza
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  2. Pablo A. Quintero
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Corresponding author

Correspondence to Nicolas Isaza .

Editor information

Editors and Affiliations

  1. Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA

    Ankit A. Bhargava

  2. Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA

    Bryan J. Wells

  3. Department of Medicine, Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

    Pablo A. Quintero

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Isaza, N., Quintero, P.A. (2022). Heart Failure with Preserved Ejection Fraction. In: Bhargava, A.A., Wells, B.J., Quintero, P.A. (eds) Handbook of Outpatient Cardiology . Springer, Cham. https://doi.org/10.1007/978-3-030-88953-1_16

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  • DOI: https://doi.org/10.1007/978-3-030-88953-1_16

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  • Online ISBN: 978-3-030-88953-1

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