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Suspicious for High-Grade Urothelial Carcinoma (SHGUC)

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Abstract

The diagnosis of suspicious for high-grade urothelial carcinoma (SHGUC) is meant to reflect the presence of a small number of urothelial cells with increased nuclear-to-cytoplasmic ratio and severe nuclear atypia that falls short for a diagnosis of HGUC, but beyond atypia that is associated with the category of atypical urothelial cells (AUC). This chapter describes the detailed quantitative and qualitative cytomorphologic criteria needed for a diagnosis of SHGUC. It also discusses the prevalence of this diagnosis in the literature and the associated risk of high-grade malignancy (ROHM).

Keywords

  • High-grade urothelial carcinoma (HGUC)
  • Suspicious for HGUC (SHGUC)
  • Atypia
  • Severe atypia.

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Correspondence to Fadi Brimo .

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Brimo, F. et al. (2022). Suspicious for High-Grade Urothelial Carcinoma (SHGUC). In: Wojcik, E.M., Kurtycz, D.F., Rosenthal, D.L. (eds) The Paris System for Reporting Urinary Cytology. Springer, Cham. https://doi.org/10.1007/978-3-030-88686-8_5

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  • DOI: https://doi.org/10.1007/978-3-030-88686-8_5

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