Abstract
The World Health Organization (WHO) Analgesic Ladder was a framework created by the WHO to provide guidance to physicians on appropriate pain relief strategies for cancer patients. It involves a three-step progression from non-opioids to weak opioids to strong opioids until sufficient pain relief is obtained. Around this central framework, adjuvant medications and procedural options are also given and recommended when deemed necessary due to ineffective pain control.
Keywords
- Cancer pain
- Palliative care
- WHO
- Analgesic ladder
- Chronic pain
This is a preview of subscription content, access via your institution.
Buying options


References
Cancer Pain Relief. Geneva: World Health Organization; 1986.
WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents. Geneva: World Health Organization. 2018. Licence: CC BY-NC-SA 3.0 IGO.
Yang J, Bauer BA, Wahner-Roedler DL, Chon TY, Xiao L. The modified WHO analgesic ladder: is it appropriate for chronic non-cancer pain? J Pain Res. 2020;13:411–7.
Ventafridda V, Tamburini M, Caraceni A, De Conno F, Naldi F. A validation study of the WHO method for cancer pain relief. Cancer. 1987;59(4):850–6.
Colleau SM, Joranson DE. Cancer Pain. 1998;11:1–5.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Hagedorn, J.M. (2022). World Health Organization Analgesic Ladder. In: Banik, R.K. (eds) Anesthesiology In-Training Exam Review. Springer, Cham. https://doi.org/10.1007/978-3-030-87266-3_67
Download citation
DOI: https://doi.org/10.1007/978-3-030-87266-3_67
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-87265-6
Online ISBN: 978-3-030-87266-3
eBook Packages: MedicineMedicine (R0)