Skip to main content

Domain Generalization for Mammography Detection via Multi-style and Multi-view Contrastive Learning

  • Conference paper
  • First Online:

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 12907))

Abstract

Lesion detection is a fundamental problem in the computer-aided diagnosis scheme for mammography. The advance of deep learning techniques have made a remarkable progress for this task, provided that the training data are large and sufficiently diverse in terms of image style and quality. In particular, the diversity of image style may be majorly attributed to the vendor factor. However, the collection of mammograms from vendors as many as possible is very expensive and sometimes impractical for laboratory-scale studies. Accordingly, to further augment the generalization capability of deep learning model to various vendors with limited resources, a new contrastive learning scheme is developed. Specifically, the backbone network is firstly trained with a multi-style and multi-view unsupervised self-learning scheme for the embedding of invariant features to various vendor-styles. Afterward, the backbone network is then recalibrated to the downstream task of lesion detection with the specific supervised learning. The proposed method is evaluated with mammograms from four vendors and one unseen public dataset. The experimental results suggest that our approach can effectively improve detection performance on both seen and unseen domains, and outperforms many state-of-the-art (SOTA) generalization methods.

Z. Li and Z. Cui—Equal contribution.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Azizi, S., et al.: Big self-supervised models advance medical image classification. arXiv preprint arXiv:2101.05224 (2021)

  2. Chen, N., et al.: Unsupervised learning of intrinsic structural representation points. In: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 9121–9130 (2020)

    Google Scholar 

  3. Chen, T., Kornblith, S., Norouzi, M., Hinton, G.: A simple framework for contrastive learning of visual representations. In: International Conference on Machine Learning, pp. 1597–1607. PMLR (2020)

    Google Scholar 

  4. Cui, Z., et al.: Structure-driven unsupervised domain adaptation for cross-modality cardiac segmentation. IEEE Trans. Med. Imaging (2021)

    Google Scholar 

  5. Dou, Q., Castro, D.C., Kamnitsas, K., Glocker, B.: Domain generalization via model-agnostic learning of semantic features. arXiv preprint arXiv:1910.13580 (2019)

  6. Kim, T., Jeong, M., Kim, S., Choi, S., Kim, C.: Diversify and match: a domain adaptive representation learning paradigm for object detection. In: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 12456–12465 (2019)

    Google Scholar 

  7. Li, H., Pan, S.J., Wang, S., Kot, A.C.: Domain generalization with adversarial feature learning. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 5400–5409 (2018)

    Google Scholar 

  8. Li, Y., et al.: Deep domain generalization via conditional invariant adversarial networks. In: Proceedings of the European Conference on Computer Vision (ECCV), pp. 624–639 (2018)

    Google Scholar 

  9. Liu, Q., Dou, Q., Heng, P.-A.: Shape-aware meta-learning for generalizing prostate MRI segmentation to unseen domains. In: Martel, A.L., et al. (eds.) MICCAI 2020. LNCS, vol. 12262, pp. 475–485. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59713-9_46

    Chapter  Google Scholar 

  10. Lotter, W., et al.: Robust breast cancer detection in mammography and digital breast tomosynthesis using an annotation-efficient deep learning approach. Nat. Med. 27(2), 244–249 (2021)

    Article  Google Scholar 

  11. Van der Maaten, L., Hinton, G.: Visualizing data using t-SNE. J. Mach. Learn. Res. 9(11) (2008)

    Google Scholar 

  12. McKinney, S.M., et al.: International evaluation of an AI system for breast cancer screening. Nature 577(7788), 89–94 (2020)

    Article  Google Scholar 

  13. Moreira, I.C., Amaral, I., Domingues, I., Cardoso, A., Cardoso, M.J., Cardoso, J.S.: INbreast: toward a full-field digital mammographic database. Acad. Radiol. 19(2), 236–248 (2012)

    Article  Google Scholar 

  14. Romera, E., Bergasa, L.M., Alvarez, J.M., Trivedi, M.: Train here, deploy there: robust segmentation in unseen domains. In: 2018 IEEE Intelligent Vehicles Symposium (IV), pp. 1828–1833. IEEE (2018)

    Google Scholar 

  15. Salim, M., et al.: External evaluation of 3 commercial artificial intelligence algorithms for independent assessment of screening mammograms. JAMA Oncol. 6(10), 1581–1588 (2020)

    Article  Google Scholar 

  16. Sowrirajan, H., Yang, J., Ng, A.Y., Rajpurkar, P.: MoCo pretraining improves representation and transferability of chest x-ray models. arXiv preprint arXiv:2010.05352 (2020)

  17. Tian, Z., Shen, C., Chen, H., He, T.: FCOS: fully convolutional one-stage object detection. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 9627–9636 (2019)

    Google Scholar 

  18. Volpi, R., Namkoong, H., Sener, O., Duchi, J.C., Murino, V., Savarese, S.: Generalizing to unseen domains via adversarial data augmentation. In: NeurIPS (2018)

    Google Scholar 

  19. Wang, S., et al.: mr\(^2\)NST: multi-resolution and multi-reference neural style transfer for mammography. In: Rekik, I., Adeli, E., Park, S.H., Valdés Hernández, M.C. (eds.) PRIME 2020. LNCS, vol. 12329, pp. 169–177. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59354-4_16

    Chapter  Google Scholar 

  20. Wang, S., Yu, L., Li, C., Fu, C.-W., Heng, P.-A.: Learning from extrinsic and intrinsic supervisions for domain generalization. In: Vedaldi, A., Bischof, H., Brox, T., Frahm, J.-M. (eds.) ECCV 2020. LNCS, vol. 12354, pp. 159–176. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-58545-7_10

    Chapter  Google Scholar 

  21. Yue, X., Zhang, Y., Zhao, S., Sangiovanni-Vincentelli, A., Keutzer, K., Gong, B.: Domain randomization and pyramid consistency: simulation-to-real generalization without accessing target domain data. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 2100–2110 (2019)

    Google Scholar 

  22. Zakharov, S., Kehl, W., Ilic, S.: DeceptionNet: network-driven domain randomization. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 532–541 (2019)

    Google Scholar 

  23. Zhang, L., et al.: Generalizing deep learning for medical image segmentation to unseen domains via deep stacked transformation. IEEE Trans. Med. Imaging 39(7), 2531–2540 (2020)

    Article  Google Scholar 

  24. Zhang, Y., Miao, S., Mansi, T., Liao, R.: Task driven generative modeling for unsupervised domain adaptation: application to X-ray image segmentation. In: Frangi, A.F., Schnabel, J.A., Davatzikos, C., Alberola-López, C., Fichtinger, G. (eds.) MICCAI 2018. LNCS, vol. 11071, pp. 599–607. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00934-2_67

    Chapter  Google Scholar 

  25. Zhou, H.-Y., Yu, S., Bian, C., Hu, Y., Ma, K., Zheng, Y.: Comparing to learn: surpassing ImageNet pretraining on radiographs by comparing image representations. In: Martel, A.L., et al. (eds.) MICCAI 2020. LNCS, vol. 12261, pp. 398–407. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59710-8_39

    Chapter  Google Scholar 

  26. Zhu, J.Y., Park, T., Isola, P., Efros, A.A.: Unpaired image-to-image translation using cycle-consistent adversarial networks. In: Proceedings of the IEEE International Conference on Computer Vision, pp. 2223–2232 (2017)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jie-Zhi Cheng .

Editor information

Editors and Affiliations

1 Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (pdf 412 KB)

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Li, Z. et al. (2021). Domain Generalization for Mammography Detection via Multi-style and Multi-view Contrastive Learning. In: de Bruijne, M., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2021. MICCAI 2021. Lecture Notes in Computer Science(), vol 12907. Springer, Cham. https://doi.org/10.1007/978-3-030-87234-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-87234-2_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-87233-5

  • Online ISBN: 978-3-030-87234-2

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics