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Medical Treatment of Hypersecretory Endocrine Disorders

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Diagnosis and Management of Endocrine Disorders in Interventional Radiology

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Abstract

In this chapter, we review the surgical and pharmacological management of hypersecretory endocrine disorders, including hyperaldosteronism, hyperparathyroidism, hyperandrogenism, pancreatic endocrine tumors, and hypercortisolism. Adrenalectomy is recommended for unilateral aldosterone producing adenomas, and mineralocorticoid receptor antagonists are used for those who cannot undergo surgery or have bilateral adenomas. Hyperparathyroidism is managed with surgery or medications, depending on the type of hyperparathyroidism and patient comorbidities. The treatment for hyperandrogenism depends on the underlying cause. Medical therapy is available for most causes of hyperandrogenism, but surgery is recommended for adrenal and ovarian tumors. Pancreatic endocrine tumors are surgically excised, but medical agents are available when needed. Hypercortisolism in Cushing’s syndrome is treated surgically, but medical therapy is available when surgery is not possible or unsuccessful. In this chapter, we also discuss the nuclear medicine options available for these disorders.

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Author information

Authors and Affiliations

  1. Division of Endocrinology, Diabetes and Metabolism, Duke University School of Medicine, Durham, NC, USA

    Diana Soliman & Ali Qamar

  2. Division of Molecular Imaging and Therapeutics, Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, NC, USA

    Jorge D. Oldan

Authors
  1. Diana Soliman
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  2. Ali Qamar
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  3. Jorge D. Oldan
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Corresponding author

Correspondence to Diana Soliman .

Editor information

Editors and Affiliations

  1. Division of Vascular and Interventional RadiologyDepartment of Radiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA

    Hyeon Yu

  2. Division of Vascular and Interventional RadiologyDepartment of Radiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA

    Charles T. Burke

  3. Division of Vascular and Interventional RadiologyDepartment of Radiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA

    Clayton W. Commander

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Soliman, D., Qamar, A., Oldan, J.D. (2022). Medical Treatment of Hypersecretory Endocrine Disorders. In: Yu, H., Burke, C.T., Commander, C.W. (eds) Diagnosis and Management of Endocrine Disorders in Interventional Radiology. Springer, Cham. https://doi.org/10.1007/978-3-030-87189-5_11

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  • DOI: https://doi.org/10.1007/978-3-030-87189-5_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-87188-8

  • Online ISBN: 978-3-030-87189-5

  • eBook Packages: MedicineMedicine (R0)

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