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Dental Diseases and Management

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This chapter discusses the current knowledge, clinical presentation, preventive strategies and management of the dental diseases known as radiation caries, chronic graft-versus-host disease-related caries (cGVHD-related caries), and periodontitis in the patient following completion of radiation therapy.


  • Dental caries
  • Graft-versus-host disease
  • Periodontitis
  • Radiation therapy

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  • DOI: 10.1007/978-3-030-86510-8_15
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Fig. 15.1


  1. Almstahl A, Wikstrom M, Fagerberg-Mohlin B. Microflora in oral ecosystems and salivary secretion rates—a 3-year follow-up after radiation therapy to the head and neck region. Arch Oral Biol. 2015;60(9):1187–95.

    CrossRef  Google Scholar 

  2. Brennan MT, et al. Dental disease before radiotherapy in patients with head and neck cancer: Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients. J Am Dent Assoc. 2017;148(12):868–77.

    CrossRef  Google Scholar 

  3. Crystal YO, Niederman R. Evidence-based dentistry update on silver diamine fluoride. Dent Clin N Am. 2019;63(1):45–68.

    CrossRef  Google Scholar 

  4. De Felice F, et al. Treatment improvement and better patient care: which is the most important one in oral cavity cancer? Radiat Oncol. 2014;9:263.

    CrossRef  Google Scholar 

  5. Deasy JO, Moiseenko V, Marks L, Chao KS, Nam J, Eisbruch A. Radiotherapy dose-volume effects on salivary gland function. Int J Radiat Oncol Biol Phys. 2010;76(3 Suppl):S58–63.

    CrossRef  Google Scholar 

  6. Marangoni-Lopes L, Rovai-Pavan G, Steiner-Oliveira C, Nobre-Dos-Santos M. Radiotherapy reduces microhardness and mineral and organic composition, and changes the morphology of primary teeth: an in vitro study. Caries Res. 2018;53(3):296–304.

    CrossRef  Google Scholar 

  7. Murdoch-Kinch CA, Kim HM, Vineberg KA, Ship JA, Eisbruch A. Dose-effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2008;72(2):373–82.

    CrossRef  Google Scholar 

  8. Silva AR, Alves FA, Berger SB, Giannini M, Goes MF, Lopes MA. Radiation-related caries and early restoration failure in head and neck cancer patients. A polarized light microscopy and scanning electron microscopy study. Support Care Cancer. 2010;18(1):83–7.

    CrossRef  Google Scholar 

  9. Sroussi HY, et al. Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis. Cancer Med. 2017;6(12):2918–31.

    CrossRef  Google Scholar 

  10. Treister N, Duncan C, Cutler C, Lehmann L. How we treat oral chronic graft-versus-host disease. Blood. 2012;120(17):3407–18.

    CrossRef  Google Scholar 

  11. Walker MP, Wichman B, Cheng AL, Coster J, Williams KB. Impact of radiotherapy dose on dentition breakdown in head and neck cancer patients. Pract Radiat Oncol. 2011;1(3):142–8.

    CrossRef  Google Scholar 

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Correspondence to Michael T. Brennan .

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Bowers, L.M., Brennan, M.T. (2022). Dental Diseases and Management. In: Nair, R. (eds) Orofacial Supportive Care in Cancer . Springer, Cham.

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  • Print ISBN: 978-3-030-86509-2

  • Online ISBN: 978-3-030-86510-8

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