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Orofacial Supportive Care in Paediatric Cancer

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Abstract

Paediatric cancer survivors are unique in many ways. The common cancers affecting children and its consequences are covered in this chapter. Common cancers affecting paediatric population and their sequelae such as taste disturbances, salivary gland complications and developmental issues of the dental tissue are covered in this chapter. Early or acute and long-term complications are described, and their management and long-term follow-up are discussed.

Keywords

  • Leukaemias
  • Solid tumours
  • NHL
  • Oral infections
  • Mucositis

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  • DOI: 10.1007/978-3-030-86510-8_13
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Bibliography

  1. Abramoff MM, Lopes NN, Lopes LA, Dib LL, Guilherme A, Caran EM, Barreto AD, Lee ML, Petrilli AS. Low-level laser therapy in the prevention and treatment of chemotherapy-induced oral mucositis in young patients. Photomed Laser Surg. 2008;26(4):393–400. https://doi.org/10.1089/pho.2007.2144.

    CrossRef  PubMed  Google Scholar 

  2. Amadori F, Bardellini E, Conti G, Pedrini N, Schumacher RF, Majorana A. Low-level laser therapy for treatment of chemotherapy-induced oral mucositis in childhood: a randomized double-blind controlled study. Lasers Med Sci. 2016;31(6):1231–6. https://doi.org/10.1007/s10103-016-1975-y. Epub 2016 Jun 6.

    CrossRef  PubMed  Google Scholar 

  3. Bardellini E, Amadori F, Majorana A. Oral hygiene grade and quality of life in children with chemotherapy-related oral mucositis: a randomized study on the impact of a fluoride toothpaste with salivary enzymes, essential oils, proteins and colostrum extract versus a fluoride toothpaste without menthol. Int J Dent Hyg. 2016a;14(4):314–9.

    CrossRef  Google Scholar 

  4. Bardellini E, Amadori F, Schumacher RF, D’Ippolito C, Porta F, Majorana A. Efficacy of a solution composed by verbascoside, polyvinylpyrrolidone (PVP) and sodium hyaluronate in the treatment of chemotherapy-induced oral mucositis in children with acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2016b;38(7):559–62.

    CrossRef  Google Scholar 

  5. Bardellini E, Amadori F, Schumacher RF, Foresti I, Majorana A. A new emerging oral infection: Raoultella planticola in a boy with haematological malignancy. Eur Arch Paediatr Dent. 2017;18(3):215–8.

    CrossRef  Google Scholar 

  6. Brennan MT, von Bültzingslöwen I, Schubert MM, Keefe D. Alimentary mucositis: putting the guidelines into practice. Support Care Cancer. 2006;14:573–9.

    CrossRef  Google Scholar 

  7. Cruz LB, Ribeiro AS, Rech A, Rosa LG, Castro CG Jr, Brunetto AL. Influence of low-energy laser in the prevention of oral mucositis in children with cancer receiving chemotherapy. Pediatr Blood Cancer. 2007;48(4):435–40.

    CrossRef  Google Scholar 

  8. Cubukçu CE, Sevinir B. Dental health indices of long-term childhood cancer survivors who had oral supervision during treatment: a case-control study. Pediatr Hematol Oncol. 2008;25:638–46.

    CrossRef  Google Scholar 

  9. De Castro JF, Abreu EG, Correia AV, da Mota Vasconcelos Brasil C, da Cruz Perez DE, de Paula Ramos Pedrosa F. Low-level laser in prevention and treatment of oral mucositis in pediatric patients with acute lymphoblastic leukemia. Photomed Laser Surg. 2013;31(12):613–8. https://doi.org/10.1089/pho.2012.3327. Epub 2013 Nov 21.

    CrossRef  PubMed  Google Scholar 

  10. De Koning BA, Philipsen-Geerling B, Hoijer M, Hählen K, Büller HA, Pieters R. Protection against chemotherapy induced mucositis by TGF-beta(2) in childhood cancer patients: results from a randomized cross-over study. Pediatr Blood Cancer. 2007;48(5):532–9.

    CrossRef  Google Scholar 

  11. Gobbo M, Verzegnassi F, Ronfani L, Zanon D, Melchionda F, Bagattoni S, Majorana A, Bardellini E, Mura R, Piras A, Petris MG, Mariuzzi ML, Barone A, Merigo E, Decembrino N, Vitale MC, Berger M, Defabianis P, Biasotto M, Ottaviani G, Zanazzo GA. Multicenter randomized, double-blind controlled trial to evaluate the efficacy of laser therapy for the treatment of severe oral mucositis induced by chemotherapy in children: laMPO RCT. Pediatr Blood Cancer. 2018;65(8):e27098.

    CrossRef  Google Scholar 

  12. Graber CJ, de Almeida KN, Atkinson JC, Javaheri D, Fukuda CD, Gill VJ, Barrett AJ, Bennett JE. Dental health and viridans streptococcal bacteremia in allogeneic hematopoietic stem cell transplant recipients. Bone Marrow Transplant. 2001;27:537–42.

    CrossRef  Google Scholar 

  13. Guo L, Shi W. Salivary biomarkers for caries risk assessment. J Calif Dent Assoc. 2013;41(2):107–18.

    PubMed  PubMed Central  Google Scholar 

  14. Hegde AM, Joshi S, Rai K, Shetty S. Evaluation of oral hygiene status, salivary characteristics and dental caries experience in acute lymphoblastic leukemic (ALL) children. J Clin Pediatr Dent. 2011;35(3):319–23.

    CrossRef  Google Scholar 

  15. Lark RL, McNeil SA, Vander Hyde K, et al. Risk factors for anaerobic bloodstream infections in bone marrow transplant recipients. Clin Infect Dis. 2001;33:338–43.

    CrossRef  Google Scholar 

  16. Lauritano D, Petruzzi M, Di Stasio D, Lucchese A. Clinical effectiveness of palifermin in prevention and treatment of oral mucositis in children with acute lymphoblastic leukaemia: a case-control study. Int J Oral Sci. 2014;6(1):27–30. https://doi.org/10.1038/ijos.2013.93. Epub 2013 Dec 20.

    CrossRef  PubMed  Google Scholar 

  17. Lucchese A, Matarese G, Ghislanzoni LH, Gastaldi G, Manuelli M, Gherlone E. Efficacy and effects of palifermin for the treatment of oral mucositis in patients affected by acute lymphoblastic leukemia. Leuk Lymphoma. 2016;57(4):820–7. https://doi.org/10.3109/10428194.2015.1081192. Epub 2015 Nov 20.

    CrossRef  PubMed  Google Scholar 

  18. Majorana A, Amadori F, Bardellini E, Campus G, Conti G, Strohmenger L, Schumacher RF, Polimeni A. Taste dysfunction in patients undergoing hematopoietic stem cell transplantation: clinical evaluation in children. Pediatr Transplant. 2015;19(5):571–5.

    CrossRef  Google Scholar 

  19. Marron A, Carratalà J, González-Barca E, Fernández-Sevilla A, Alcaide F, Gudiol F. Serious complications of bacteremia caused by viridans streptococci in neutropenic patients with cancer. Clin Infect Dis. 2000;31:1126–30.

    CrossRef  Google Scholar 

  20. McGuire E. Breastfeeding and high maternal body mass index. Breastfeed Rev. 2013;21:7–14.

    PubMed  Google Scholar 

  21. McLaren L, Patterson S, Thawer S, Faris P, McNeil D, Potestio M, Shwart L. Measuring the short-term impact of fluoridation cessation on dental caries in Grade 2 children using tooth surface indices. Community Dent Oral Epidemiol. 2016;44:274–82.

    CrossRef  Google Scholar 

  22. Moynihan PJ, Kelly SA. Effect on caries of restricting sugars intake: systematic review to inform WHO guidelines. J Dent Res. 2014;93(1):8–18.

    CrossRef  Google Scholar 

  23. Newton JT. Interdisciplinary health promotion: a call for theory-based interventions drawing on the skills of multiple disciplines. Community Dent Oral Epidemiol. 2012;40:49–54.

    CrossRef  Google Scholar 

  24. Ritter AV, Preisser JS, Puranik CP, Chung Y, Bader JD, Shugars DA, Makhija S, Vollmer WM. A predictive model for root caries incidence. Caries Res. 2016;50:271–8.

    CrossRef  Google Scholar 

  25. Suma Sogi HP, Hugar SM, Nalawade TM, Sinha A, Hugar S, Mallikarjuna RM. Knowledge, attitude, and practices of oral health care in prevention of early childhood caries among parents of children in Belagavi city: a questionnaire study. J Family Med Prim Care. 2016;5:286–90.

    CrossRef  Google Scholar 

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Correspondence to Alessandra Majorana .

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Majorana, A., Bardellini, E. (2022). Orofacial Supportive Care in Paediatric Cancer. In: Nair, R. (eds) Orofacial Supportive Care in Cancer . Springer, Cham. https://doi.org/10.1007/978-3-030-86510-8_13

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  • DOI: https://doi.org/10.1007/978-3-030-86510-8_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-86509-2

  • Online ISBN: 978-3-030-86510-8

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