Abstract
Kidney transplantation is the best available modality among the renal replacement therapies offered to a patient with chronic kidney disease stage 5. It provides near normal quality of life to the patient. Both the donor (either diseased or living-related) and the recipient undergo a battery of laboratory tests before transplantation. Induction therapy is used immediately after surgery to prevent acute rejection of the kidney. Several immunosuppressive drugs such as corticosteroids, cyclosporine, tacrolimus, mycophenolate mofetil, and sirolimus are used to prevent chronic rejection of the recipient kidney. Immunosuppression causes several complications such as infections, malignancies, cardiovascular disease, bone mineral disorders, diabetes, and urologic problems. Recurrence of original kidney disease and proteinuria also occur in the transplanted kidney.
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Reddi, A.S. (2022). Transplantation. In: Absolute Nephrology Review. Springer, Cham. https://doi.org/10.1007/978-3-030-85958-9_11
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DOI: https://doi.org/10.1007/978-3-030-85958-9_11
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