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IFIP International Conference on Advances in Production Management Systems

APMS 2021: Advances in Production Management Systems. Artificial Intelligence for Sustainable and Resilient Production Systems pp 98–106Cite as

A Framework Integrating Internet of Things and Blockchain in Clinical Trials Reverse Supply Chain

Part of the IFIP Advances in Information and Communication Technology book series (IFIPAICT,volume 631)

Abstract

Efficiency and resilience of the clinical trials supply chain are of particular prevalence in the current global context. The unique characteristic of the reverse logistics flow in the supply chains for clinical trials is the foundation for the digital transformation framework presented in this paper. This paper proposes a novel framework that integrates internet of things (IoT) and blockchain technology for the reverse logistics supply chain for clinical trials. The framework is implemented in a Contract Research Organisation operating clinical trials in Europe and North Africa and results are discussed. The main contribution of the proposed novel framework is the integration and interaction of both IoT and blockchain in a reverse logistics process.

Keywords

  • IoT
  • Blockchain
  • Reverse logistics
  • Clinical trials

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References

  1. Tseng, J.-H., Liao, Y.-C., Chong, B., Liao, S.-W.: Governance on the drug supply chain via gcoin blockchain. Int. J. Environ. Res. Public Health 15(6), 1055–1063 (2018)

    CrossRef  Google Scholar 

  2. HealthNautica. https://www.healthnautica.com/comppages/index.asp. Accessed 15 Mar 2021

  3. FACTOM - Introducing Honesty to Record-Keeping. https://bitcointalk.org/index.php?topic=850070.0. Accessed 15 Mar 2021

  4. Gem: The Best Crypto Portfolio Tracker Does the Work for You. https://gem.co/. Accessed 15 Mar 2021

  5. Tehrani, N., Jin, Y.: How advances in the Internet of Things (Iot) devices and wearable technology will impact the pharmaceutical industry. RA J. Appl. Res. 4(3), 1530–1533 (2018)

    Google Scholar 

  6. Li, W., Chai, Y., Khan, F., Jan, S.R.U., Verma, S., Menon, V.G., Kavita, X.L.: A comprehensive survey on machine learning-based big data analytics for IoT-enabled smart healthcare system. Mob. Netw. Appl. 26(1), 234–252 (2021). https://doi.org/10.1007/s11036-020-01700-6

    CrossRef  Google Scholar 

  7. Singh, M., Katiyar, D., Singhal, S.: Blockchain technology in management of clinical trials: a review of its applications, regulatory concerns and challenges. Mater. Today Proc. (2021, in press). https://doi.org/10.1016/j.matpr.2021.04.095, https://www.sciencedirect.com/science/article/pii/S2214785321029515

  8. Yuan, Y., Wang, F-Y.: Towards blockchain-based intelligent transportation systems. In: IEEE 19th International Conference on Intelligent Transportation Systems (ITSC), Rio de Janeiro, Brazil, pp. 2663–8, IEEE (2016)

    Google Scholar 

  9. Hewa, T., Ylianttila, M., Liyanage, M.: Survey on blockchain based smart contracts: applications, opportunities and challenges. J. Netw. Comput. Appl. 177(1), 102857 (2021)

    CrossRef  Google Scholar 

  10. Imeri, A., Khadraoui, D.: The security and traceability of shared information in the process of transportation of dangerous goods. In: 2018 9th IFIP International Conference on New Technologies, Mobility and Security (NTMS), Paris, France, pp. 1–5. IEEE (2018)

    Google Scholar 

  11. Nasih, S., Arezki, S., Gadi, T.: Enhancement of supply chain management by integrating Blockchain technology. In: 2019 1st International Conference on Smart Systems and Data Science (ICSSD), Rabat, Morocco, pp. 1–2. IEEE (2019)

    Google Scholar 

  12. Merkaš, Z., Perkov, D., Bonin, V.: The significance of blockchain technology in digital transformation of logistics and transportation. Int. J. E-Serv. Mob. Appl. 12(1), 1–20 (2020)

    CrossRef  Google Scholar 

  13. Zheng, Z., et al.: An overview on smart contracts: Challenges, advances and platforms. Future Gener. Comput. Syst. 105(1), 475–491 (2020)

    CrossRef  Google Scholar 

  14. Alahmadi, A., Lin, X.: Towards secure and fair IIoT-enabled supply chain management via blockchain-based smart contracts. In: ICC 2019 - 2019 IEEE International Conference on Communications (ICC), Shanghai, China, pp. 1–7. IEEE (2019)

    Google Scholar 

  15. Jangir, S., Muzumdar, A., Jaiswal, A., Modi, C.N., Chandel, S., Vyjayanthi, C.: A novel framework for pharmaceutical supply chain management using distributed ledger and smart contracts. In: 2019 10th International Conference on Computing, Communication and Networking Technologies (ICCCNT), Kanpur, India, pp. 1–7. IEEE (2019)

    Google Scholar 

  16. Arumugam, S.S., et al.: IOT enabled smart logistics using smart contracts. In: 2018 8th International Conference on Logistics, Informatics and Service Sciences (LISS), Toronto, Canada, pp. 1–6. IEEE (2018)

    Google Scholar 

  17. Salah, K., Nizamuddin, N., Jayaraman, R., Omar, M.: Blockchain-based soybean traceability in agricultural supply chain. IEEE Access 7(1), 73295–73305 (2019)

    CrossRef  Google Scholar 

  18. Benchoufi, M., Ravaud, P.: Blockchain technology for improving clinical research quality. Trials 18(1), 335–340 (2017)

    CrossRef  Google Scholar 

  19. Shae, Z., Tsai, J.J.P.: On the design of a blockchain platform for clinical trial and precision medicine. In: 2017 IEEE 37th International Conference on Distributed Computing Systems (ICDCS), Atlanta, USA, pp. 1972–1980. IEEE (2017)

    Google Scholar 

  20. Angeletti, F., Chatzigiannakis, I., Vitaletti, A.: Towards an architecture to guarantee both data privacy and utility in the first phases of digital clinical trials. Sensors 18(12), 4175–4202 (2018)

    CrossRef  Google Scholar 

  21. Maslove, D.M., Klein, J., Brohman, K., Martin, P.: Using blockchain technology to manage clinical trials data: a proof-of-concept study. JMIR Med. Inform. 6(4), e11949 (2018)

    CrossRef  Google Scholar 

  22. Benchoufi, M., Porcher, R., Ravaud, P.: Blockchain protocols in clinical trials: transparency and traceability of consent. F1000Res 6(1), 66 (2017)

    Google Scholar 

  23. Khatoon, A.: A blockchain-based smart contract system for healthcare management. Electronics 9(1), 94–117 (2020)

    CrossRef  MathSciNet  Google Scholar 

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Acknowledgements

This work was supported by the Swiss National Science Foundation under project n° [176349].

Author information

Authors and Affiliations

  1. Faculty of Business and Economics, University of Lausanne, Lausanne, Switzerland

    Yvonne Badulescu

  2. Geneva School of Business Administration, University of Applied Sciences Western Switzerland (HES-SO), Rue de la Tambourine 17, 1227, Carouge, Switzerland

    Yvonne Badulescu & Naoufel Cheikhrouhou

Authors
  1. Yvonne Badulescu
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  2. Naoufel Cheikhrouhou
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Corresponding author

Correspondence to Yvonne Badulescu .

Editor information

Editors and Affiliations

  1. IMT Atlantique, Nantes, France

    Alexandre Dolgui

  2. Centrale Nantes, Nantes, France

    Prof. Alain Bernard

  3. IMT Atlantique, Nantes, France

    David Lemoine

  4. ZF Friedrichshafen AG, Friedrichshafen, Germany

    Gregor von Cieminski

  5. Tecnológico de Monterrey, Mexico City, Mexico

    David Romero

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Badulescu, Y., Cheikhrouhou, N. (2021). A Framework Integrating Internet of Things and Blockchain in Clinical Trials Reverse Supply Chain. In: Dolgui, A., Bernard, A., Lemoine, D., von Cieminski, G., Romero, D. (eds) Advances in Production Management Systems. Artificial Intelligence for Sustainable and Resilient Production Systems. APMS 2021. IFIP Advances in Information and Communication Technology, vol 631. Springer, Cham. https://doi.org/10.1007/978-3-030-85902-2_11

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  • DOI: https://doi.org/10.1007/978-3-030-85902-2_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-85901-5

  • Online ISBN: 978-3-030-85902-2

  • eBook Packages: Computer ScienceComputer Science (R0)

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