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Microbiomes in the Intestine of Developing Pigs: Implications for Nutrition and Health

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Recent Advances in Animal Nutrition and Metabolism

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1354))

Abstract

The past decade has seen an expansion of studies on the role of gut microbiome in piglet nutrition and health. With the help of culture-independent sequencing techniques, the colonization of gut microbiota and their implication in physiology are being investigated in depth. Immediately after birth, the microbes begin to colonize following an age-dependent trajectory, which can be modified by maternal environment, diet, antibiotics, and fecal microbiota transplantation. The early-life gut microbiome is relatively simple but enriched with huge metabolic potential to utilize milk oligosaccharides and affect the epithelial function. After weaning, the gut microbiome develops towards a gradual adaptation to the introduction of solid food, with an enhanced ability to metabolize amino acids, fibers, and bile acids. Here we summarize the compositional and functional difference of the gut microbiome in the keystone developing phases, with a specific focus on the use of different nutritional approaches based on the phase-specific gut microbiome.

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Acknowledgements

This work was funded by the Natural Science Foundation of China (32030104, 31902166, 31430082) and National Key Basic Research Program of China (2013CB127300).

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Authors and Affiliations

  1. Laboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China

    Chunlong Mu, Yu Pi, Chuanjian Zhang & Weiyun Zhu

  2. National Center for International Research On Animal Gut Nutrition, Nanjing Agricultural University, Nanjing, 210095, China

    Chunlong Mu, Yu Pi, Chuanjian Zhang & Weiyun Zhu

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  1. Chunlong Mu
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Correspondence to Weiyun Zhu .

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  1. Department of Animal Science, Texas A&M University, College Station, TX, USA

    Guoyao Wu

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Mu, C., Pi, Y., Zhang, C., Zhu, W. (2022). Microbiomes in the Intestine of Developing Pigs: Implications for Nutrition and Health. In: Wu, G. (eds) Recent Advances in Animal Nutrition and Metabolism. Advances in Experimental Medicine and Biology, vol 1354. Springer, Cham. https://doi.org/10.1007/978-3-030-85686-1_9

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