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Accelerated Crosslinking: The New Epithelium-Off

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Keratoconus

Abstract

Conventional riboflavin UV-A induced corneal crosslinking (CXL) with epithelium removal (Epi-Off) represents a cost-effective treatment with documented long-term efficacy in stabilizing progressive Keratoconus and secondary ectasia. The accelerated 9 mW/5.4 J/cm2 for 10 min (ACXL) protocol—supported by photochemistry, microstructural and long-term clinical data is a candidate to be the natural evolution of the original Dresden Epi-Off CXL treatment for the management of early progressive corneal ectasia, thus optimizing clinic workflow.

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Authors and Affiliations

  1. Department of Ophthalmology, C. G. Carus University Hospital, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany

    Frederik Raiskup & Robert Herber

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  1. Frederik Raiskup
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  2. Robert Herber
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Correspondence to Frederik Raiskup .

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Editors and Affiliations

  1. Watany Eye Hospital, Cairo, Egypt

    Ashraf Armia

  2. Ophthalmology Unit, Department of Medical, Surgical and Experimental Sciences, Italy and Siena Crosslinking Center, Italy, University of Sassari, Siena, Italy

    Cosimo Mazzotta

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Raiskup, F., Herber, R. (2022). Accelerated Crosslinking: The New Epithelium-Off. In: Armia, A., Mazzotta, C. (eds) Keratoconus. Springer, Cham. https://doi.org/10.1007/978-3-030-84506-3_6

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  • DOI: https://doi.org/10.1007/978-3-030-84506-3_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-84505-6

  • Online ISBN: 978-3-030-84506-3

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