Abstract
Neuroblastoma are tumors derived from primitive cells of neural origin arising in many sites along the neural crest/sympathetic chain. They are potentially highly malignant but of unpredictable behavior and treated by a combination of surgical resection (if possible) and chemotherapy.
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Notes
- 1.
Hiroyuki Shimada – Japanese pathologist, latterly working in Los Angeles, USA.
- 2.
Johann F. Horner (1831–1886) – Swiss ophthalmologist named triad as meiosis, ptosis and enopthalmos, but can have ↓ facial sweating and iris color change. Described many times before Horner’s case in 1869.
Further Reading
Neuroblastoma. A neural crest derived embryonal malignancy. Front Mol Neurosci. 2019; https://doi.org/10.3389/fnmol.2019.00009.
Iwanaka T, Kawashima H, Uchida H. The laparoscopic approach of neuroblastoma. Semin Pediatr Surg. 2007;16:259–65.
The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol. 2009;27:289–97.
Nuchtern JG, London WB, Barnewolt CE, et al. A prospective study of expectant observation as primary therapy for neuroblastoma in young infants, a COG study. Ann Surg. 2012;256:573–80.
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Qazi, A., Haider, N., Squire, R. (2022). Neuroblastoma. In: Sinha, C.K., Davenport, M. (eds) Handbook of Pediatric Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-84467-7_45
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DOI: https://doi.org/10.1007/978-3-030-84467-7_45
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