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Intestinal Malrotation

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Handbook of Pediatric Surgery

Abstract

Malrotation occurs when the normal process of intestinal rotation is not complete or is erroneous. The commonest variant being the failure of the final 90° anticlockwise rotation taking the cecum from the right upper quadrant to the right iliac fossa and being fixed in a subhepatic position. The most feared complication of malrotation is volvulus and intestinal infarction though malrotation of itself can present with bile vomiting in the absence of volvulus. The commonest surgical procedure performed is separation and widening of the mesentery at its narrowest point and deliberate positioning of the two ends of the midgut as far from each other as possible with the duodenojejunal flexure on the right side and the cecum and colon on the left—Ladd’s procedure.

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Notes

  1. 1.

    Waugh GEA (1920) The morbid consequences of a mobile ascending colon. Br J Surg 7:343.

  2. 2.

    Hardikar et al. Multisystem obstruction with cholestasis, pigmentary retinopathy, and cleft palate: a new syndrome? Am J Med Genet. 44: 13–17, 1992.

  3. 3.

    Martinez-Frias ML, Frias JL, Galan E, et al. Tracheoesophageal fistula, gastrointestinal abnormalities, hypospadias, and prenatal growth deficiency. Am J Med Genet 1992; 3:352–355.

  4. 4.

    Fryns JP, et al. A new lethal syndrome with cloudy corneae, diaphragmatic defects and distal limb deformities. Hum Genet 1979;50:65–70.

  5. 5.

    William E Ladd (1880–1967)—American surgeon working in Boston, MA, regarded as the father of American pediatric surgery and pioneer in many areas.

Further Reading

  • Frazer JE, Robbins RH. On the factors concerned in causing malrotation of the intestines in man. J. Anat Physiol. 1915;51:75–110.

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  • Miller AJW, Rode H, Cywes S. Malrotation and volvulus in infancy and childhood. Seminars Pediatr Surg. 2003;12:229–36.

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  • Penco JMM, Murillo JC, Hernandez A, et al. Anomalies of intestinal rotation and fixation: consequences of late diagnosis beyond two years of age. Pediatr Surg Int. 2007;23:723–30.

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  • Martin V, Shaw-Smith C. Review of genetic factors in intestinal malrotation. Pediatr Surg Int. 2010;26:769–81.

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  • Bartholmot C, Faure J, Grosjean F, et al. Prenatal diagnosis of antenatal midgut volvulus: specific ultrasound features. Prenatal Diagnosis. 2019;39:16–25.

    PubMed  Google Scholar 

  • Catania V, Lauriti G, Pierro A, et al. Open versus laparoscopic approach for intestinal malrotation in infants and children: a systematic review and meta-analysis. Pediatr Surg Int. 2016;32:1157–64.

    Article  Google Scholar 

  • Graziano K, Islam S, Dasgupta R, et al. Asymptomatic malrotation: diagnosis and surgical management. An American Pediatric Surgical Association outcomes and evidence based practice committee systematic review. J Pediatr Surg. 2015;50:1783–90.

    Article  Google Scholar 

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Njere, I., Sinha, C.K., Davenport, M. (2022). Intestinal Malrotation. In: Sinha, C.K., Davenport, M. (eds) Handbook of Pediatric Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-84467-7_18

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  • DOI: https://doi.org/10.1007/978-3-030-84467-7_18

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-84466-0

  • Online ISBN: 978-3-030-84467-7

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