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Prolactinoma in Pregnancy

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A Case-Based Guide to Clinical Endocrinology

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Abstract

Prolactinomas in pregnancy may present a medical challenge due to concerns about tumor growth during pregnancy from elevated circulating estrogen levels. It is generally recommended and accepted to stop dopamine agonists in pregnant patients with microprolactinomas or macroprolactinomas as long is there is no invasion or compression of surrounding sellar structures. Cabergoline and bromocriptine are FDA pregnancy category B and have been observed to be safe in pregnancy (including during organogenesis). Serum prolactin levels and pituitary MRI are not routinely needed during pregnancy unless clinical compressive symptoms develop. Pregnant patients with prolactinomas should be monitored at least once every trimester for the development of compressive symptoms.

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Authors and Affiliations

  1. Department of Medicine, Section of Endocrinology, Diabetes and Nutrition, Boston University Medical Center, Boston, MA, USA

    Danica M. Vodopivec & Sonia Ananthakrishnan

Authors
  1. Danica M. Vodopivec
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  2. Sonia Ananthakrishnan
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Correspondence to Sonia Ananthakrishnan .

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Editors and Affiliations

  1. Thyroid Research Unit, Department of Medicine, Icahn School of Medicine at Mount Sinai and James J. Peters VA Medical Center, New York, NY, USA

    Terry F. Davies

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Vodopivec, D.M., Ananthakrishnan, S. (2022). Prolactinoma in Pregnancy. In: Davies, T.F. (eds) A Case-Based Guide to Clinical Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-030-84367-0_34

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  • DOI: https://doi.org/10.1007/978-3-030-84367-0_34

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-84366-3

  • Online ISBN: 978-3-030-84367-0

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