In the following pages various examples and issues on the use and implementation of digital and computational pathology into clinical practice will be listed and discussed. Attempts to be detailed and comprehensive must fail because it is a very fast moving and growing field as any technology market, and any strive for completeness will remain unsuccessful. However, the reader is encouraged to read the original literature or to contact other domain experts in the field of digital and computational pathology to design the best possible solution for each personal and laboratory situation.