Skip to main content

Whole Slide Image Analysis

  • Chapter
  • First Online:
Whole Slide Imaging
  • 912 Accesses

Abstract

The next several years in digital pathology will certainly be exciting. As adoption of digital workflows continues, the opportunities to use image analysis will increase. The combination of AI techniques with traditional image analysis techniques may yield results which are superior to either of the techniques applied independently. The use of these techniques may complement the expertise of pathologists to provide improvements in diagnostic accuracy, efficiency, and patient care.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. https://www.selectscience.net/product-news/aperio-scanscope-systems-ce-marked-as-a-primary-in-vitro-diagnostic-aid/?artID=25313. Accessed 09/07/2021.

  2. https://www.fda.gov/news-events/press-announcements/fda-allows-marketing-first-whole-slide-imaging-system-digital-pathology. Accessed 09/07/2021.

  3. https://www.cap.org/covid-19/remote-sign-out-faqs. Accessed 09/07/2021.

  4. CAP Anatomic Pathology checklist 2018.

    Google Scholar 

  5. Bautista PA, Hashimoto N, Yagi Y. Color standardization in whole slide imaging using a color calibration slide. J Pathol Inform. 2014;5:4.

    Article  Google Scholar 

  6. https://www.cms.gov/apps/physician-fee-schedule/search/search-criteria.aspx. Accessed 09/07/2021.

  7. https://en.wikipedia.org/wiki/Pixel. Accessed 09/07/2021.

  8. https://en.wikipedia.org/wiki/List_of_color_spaces_and_their_uses. Accessed 09/07/2021.

  9. Hunt RWG. The reproduction of colour. 6th edn, © 2004 John Wiley & Sons, Ltd. ISBN: 0-470-02425-9.

    Google Scholar 

  10. https://www.olympus-lifescience.com/en/camera/color/dp74/#!cms[tab]=%2Fcamera%2Fcolor%2Fdp74%2Fspecifications. Accessed 09/07/2021.

  11. https://www.microscopyu.com/tutorials/ccd-resolution-for-optical-microscopy. Accessed 09/07/2021.

  12. http://www.planar.com/blog/2018/2/23/what-is-pixel-pitch-and-why-does-it-matter/. Accessed 09/07/2021.

  13. Zarella MD, Bowman D, Aeffner F, et al. A Practical Guide to Whole Slide Imaging: A White Paper From the Digital Pathology Association. Arch Pathol Lab Med. 2019;143(2):222–34. https://doi.org/10.5858/arpa.2018-0343-RA.

  14. Ionescu DN, Downes MR, Christofides A, Tsao MS. Harmonization of PD-L1 testing in oncology: a Canadian pathology perspective. Curr Oncol. 2018;25(3):e209–16. https://doi.org/10.3747/co.25.4031.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. https://www.agilent.com/cs/library/usermanuals/public/29276_22C3_pharmdx_uc_interpretation_manual_us.pdf. Accessed 09/07/2021.

  16. Della Mea V, Baroni GL, Pilutti D, Di Loreto C. SlideJ: an ImageJ plugin for automated processing of whole slide images. PLoS One. 2017;12(7):e0180540. https://doi.org/10.1371/journal.pone.0180540.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. https://imagej.nih.gov/ij/docs/index.html. Accessed 09/07/2021.

  18. Lee LH, Mansoor A, Wood B, Nelson H, Higa D, Naugler C. Performance of CellaVision DM96 in leukocyte classification. J Pathol Inform. 2013;4:14. Published 2013 Jun 29. https://doi.org/10.4103/2153-3539.114205.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Abràmoff MD, Lavin PT, Birch M, Shah N, Folk JC. Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices. NPJ Digit Med. 2018;1:39. Published 2018 Aug 28. https://doi.org/10.1038/s41746-018-0040-6.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Dangott, B. (2022). Whole Slide Image Analysis. In: Parwani, A.V. (eds) Whole Slide Imaging. Springer, Cham. https://doi.org/10.1007/978-3-030-83332-9_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-83332-9_12

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-83331-2

  • Online ISBN: 978-3-030-83332-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics