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Coxiella burnetii

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Abstract

Management of C. burnetii infections, a worlwide zoonotic disease (Q fever), fully aligns with the “one health” concept whereby veterinary and human medicine must be tackled collectively for the prevention of such zoonotic diseases. Molecular epidemiology and surveillance based on methods which can discriminate between strains is an important and somehow mandatory technique when tracing back infections and outbreaks to their source. In Q fever molecular typing and sequencing still presents real challenges, not only in veterinary medicine, but especially in human medicine, and is far beyond becoming a routine diagnostic tool for molecular epidemiology and surveillance. In this chapter we give a short summary and utility of established typing methods, showing efforts to overcome the inherent problems of low target DNA-amounts, and providing insights into current database networks facilitating typing and sequencing information applicable to those from a broad range of stakeholders from researchers, veterinarians, and those working in human medical disciplines.

Keywords

  • Coxiella burnetii
  • Q fever
  • Zoonosis
  • One health
  • Molecular epidemiology
  • Molecular typing
  • Sequencing
  • Database

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Frangoulidis, D., Walter, M.C., Fasemore, A.M., Cutler, S.J. (2022). Coxiella burnetii . In: de Filippis, I. (eds) Molecular Typing in Bacterial Infections, Volume II. Springer, Cham. https://doi.org/10.1007/978-3-030-83217-9_12

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