Abstract
Presently, mass spectrometry is one of the most extensively used analytical techniques in bioanalysis. High sensitivity, selectivity, and resolution, which are essential features for the analysis of complex matrices such as biological samples, can be achieved when this technique is applied. Therefore, the aim of this chapter consists of describing the general principles of mass spectrometry and the instrumentation (ion sources, mass analyzers, and detectors) usually employed in bioanalysis, including hyphenated techniques. Afterwards, the most prominent applications of mass spectrometry currently used in bioanalysis—omic sciences (proteomics, metabolomics, metallomics) and imaging—will also be discussed.
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Martins, D.N., Vendramini, P.H., Simionato, A.V.C., Sussulini, A. (2022). Introduction to Bioanalytical Mass Spectrometry. In: Kubota, L.T., da Silva, J.A.F., Sena, M.M., Alves, W.A. (eds) Tools and Trends in Bioanalytical Chemistry. Springer, Cham. https://doi.org/10.1007/978-3-030-82381-8_23
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